microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4736 Gene

Subcategory (RNA class) for MIR4736 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4736 Gene

  • MicroRNA 4736 2 3 5
  • Hsa-Mir-4736 2 3
  • MIR4736 2 5
  • MIMAT0019862 50
  • MI0017373 50

External Ids for MIR4736 Gene

Previous GeneCards Identifiers for MIR4736 Gene

  • GC17U901635
  • GC17M056417

Summaries for MIR4736 Gene

Entrez Gene Summary for MIR4736 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4736 Gene

MIR4736 (MicroRNA 4736) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4736 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4736 Gene

Genomics for MIR4736 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4736 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J058328 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -1.5 -1495 21 ARHGAP35 CEBPG SP1 HNRNPL CREB1 CTCF PRDM10 ZNF512 RFX1 LEF1 TSPOAP1 MN297491 MIR4736 TSPOAP1-AS1 SRSF1 MKS1 SMG8 SUPT4H1 VEZF1 TRIM37
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4736 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4736 Gene

Genomic Locations for MIR4736 Gene
chr17:58,335,976-58,336,022
(GRCh38/hg38)
Size:
47 bases
Orientation:
Minus strand
chr17:56,413,337-56,413,383
(GRCh37/hg19)
Size:
47 bases
Orientation:
Minus strand

Genomic View for MIR4736 Gene

Genes around MIR4736 on UCSC Golden Path with GeneCards custom track
MIR4736 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4736 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4736 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4736 Gene

Proteins for MIR4736 Gene

Post-translational modifications for MIR4736 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4736 Gene

Domains & Families for MIR4736 Gene

Gene Families for MIR4736 Gene

HGNC:
genes like me logo Genes that share domains with MIR4736: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4736 Gene

Function for MIR4736 Gene

Phenotypes From GWAS Catalog for MIR4736 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4736 Gene

Localization for MIR4736 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4736 Gene

Pathways & Interactions for MIR4736 Gene

PathCards logo

SuperPathways for MIR4736 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4736 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4736 Gene

Drugs & Compounds for MIR4736 Gene

No Compound Related Data Available

Transcripts for MIR4736 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4736 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E7FB_9606 precursor_RNA 47 4

HGNC: 41804,

RefSeq: NR_039889,

Ensembl: ENST00000581591 (view in UCSC) ,

miRBase: MI0017373,

URS0000077E9F_9606 miRNA 19 3

RefSeq: NR_039889,

miRBase: MIMAT0019862,

ENA: FR773026.1:1..19:ncRNA,

MIR4736 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4736 Gene

No ASD Table

Relevant External Links for MIR4736 Gene

GeneLoc Exon Structure for
MIR4736

No data available for mRNA/cDNA for MIR4736 Gene

Expression for MIR4736 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4736 Gene

Orthologs for MIR4736 Gene

Evolution for MIR4736 Gene

ENSEMBL:
Gene Tree for MIR4736 (if available)
TreeFam:
Gene Tree for MIR4736 (if available)

No data available for Orthologs for MIR4736 Gene

Paralogs for MIR4736 Gene

No data available for Paralogs for MIR4736 Gene

Variants for MIR4736 Gene

Additional dbSNP identifiers (rs#s) for MIR4736 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4736 Gene

Variant ID Type Subtype PubMed ID
nsv457860 CNV loss 19166990
nsv509663 CNV insertion 20534489
nsv517229 CNV gain+loss 19592680
nsv575799 CNV loss 21841781

Additional Variant Information for MIR4736 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4736

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4736 Gene

Disorders for MIR4736 Gene

No disorders were found for MIR4736 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4736 Gene

Publications for MIR4736 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4736 Gene

Sources for MIR4736 Gene