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Aliases for MIR4731 Gene

Subcategory (RNA class) for MIR4731 Gene


Quality Score for this RNA gene is


Aliases for MIR4731 Gene

  • MicroRNA 4731 2 3 5
  • Hsa-Mir-4731 3

External Ids for MIR4731 Gene

Previous GeneCards Identifiers for MIR4731 Gene

  • GC17U901660
  • GC17M015157

Summaries for MIR4731 Gene

Entrez Gene Summary for MIR4731 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4731 Gene

MIR4731 (MicroRNA 4731) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4731 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4731 Gene

Genomics for MIR4731 Gene

GeneHancer (GH) Regulatory Elements for MIR4731 Gene

Promoters and enhancers for MIR4731 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I015250 Enhancer 0.8 FANTOM5 ENCODE dbSUPER 550.8 +0.9 868 0.4 CREB1 GC17M015252 GC17M015254 MIR4731 GC17M015240 PMP22
GH17I015251 Enhancer 0.2 dbSUPER 550.8 -1.6 -1554 2.8 GC17M015252 GC17M015254 GC17M015256 MIR4731 TEKT3 GC17M015257 PMP22
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4731 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4731 Gene

Genomic Locations for MIR4731 Gene
70 bases
Minus strand

Genomic View for MIR4731 Gene

Genes around MIR4731 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4731 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4731 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4731 Gene

Proteins for MIR4731 Gene

Post-translational modifications for MIR4731 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4731 Gene

Domains & Families for MIR4731 Gene

Gene Families for MIR4731 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4731: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4731 Gene

Function for MIR4731 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4731 Gene

Localization for MIR4731 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4731 Gene

Pathways & Interactions for MIR4731 Gene

SuperPathways for MIR4731 Gene

No Data Available

Interacting Proteins for MIR4731 Gene

Gene Ontology (GO) - Biological Process for MIR4731 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4731 Gene

Drugs & Compounds for MIR4731 Gene

No Compound Related Data Available

Transcripts for MIR4731 Gene

mRNA/cDNA for MIR4731 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4731 Gene

No ASD Table

Relevant External Links for MIR4731 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4731 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4731 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4731 Gene

Orthologs for MIR4731 Gene

Evolution for MIR4731 Gene

Gene Tree for MIR4731 (if available)
Gene Tree for MIR4731 (if available)

No data available for Orthologs for MIR4731 Gene

Paralogs for MIR4731 Gene

No data available for Paralogs for MIR4731 Gene

Variants for MIR4731 Gene

Sequence variations from dbSNP and Humsavar for MIR4731 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000362801 -- 15,253,547(-) C/T upstream_transcript_variant
rs1000701735 -- 15,251,620(-) T/C downstream_transcript_variant
rs1001399548 -- 15,252,943(-) C/T upstream_transcript_variant
rs1003138618 -- 15,251,582(-) G/A downstream_transcript_variant
rs1004911619 -- 15,252,385(-) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4731 Gene

Variant ID Type Subtype PubMed ID
esv3640064 CNV loss 21293372
esv3640062 CNV loss 21293372

Additional Variant Information for MIR4731 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4731 Gene

Disorders for MIR4731 Gene

Additional Disease Information for MIR4731

No disorders were found for MIR4731 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4731 Gene

Publications for MIR4731 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. The "melanoma-enriched" microRNA miR-4731-5p acts as a tumour suppressor. (PMID: 27331623) Stark MS … Hayward NK (Oncotarget 2016) 3

Products for MIR4731 Gene

Sources for MIR4731 Gene

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