microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4729 Gene

Subcategory (RNA class) for MIR4729 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4729 Gene

  • MicroRNA 4729 2 3 5
  • Hsa-Mir-4729 2 3
  • MIR4729 2 5
  • MIMAT0019851 50
  • MI0017366 50

External Ids for MIR4729 Gene

Previous GeneCards Identifiers for MIR4729 Gene

  • GC17U901637
  • GC17P057447

Summaries for MIR4729 Gene

Entrez Gene Summary for MIR4729 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4729 Gene

MIR4729 (MicroRNA 4729) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4729 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4729 Gene

Genomics for MIR4729 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4729 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J059364 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 +4.0 3973 10.5 CEBPG GATAD2A ATF7 TEAD4 PRDM10 REST TFE3 LEF1 SOX13 IKZF1 YPEL2 DHX40 SKA2 RPS6KB1 MIR4729 piR-31162-210 NONHSAG022352.2
GH17J059386 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +21.4 21432 2.6 PKNOX1 EP300 HES1 HMBOX1 EGR1 ZNF444 MAFG ZNF8 ZFHX2 NR2F1 YPEL2 TEX14 piR-31162-210 MIR4729 NONHSAG022352.2 DHX40
GH17J059377 Enhancer 0.6 ENCODE dbSUPER 0.4 +12.3 12275 2.7 FOXA1 FOXA2 RAD21 MAZ JUN GATA2 YPEL2 DHX40 MIR4729 piR-31162-210 NONHSAG022352.2
GH17J059391 Enhancer 0.7 dbSUPER 0.3 +26.7 26727 1.7 CREB1 ATF7 FOXA1 RXRB SOX13 ZNF512B FOXA2 TEAD1 SAP130 NCOA3 piR-31162-210 piR-45504-240 piR-56022-231 piR-43099-259 piR-55281-272 DHX40 TEX14 MIR4729 NONHSAG022352.2 YPEL2
GH17J059375 Enhancer 0.4 ENCODE dbSUPER 0.4 +9.5 9549 0 MLLT1 YPEL2 MIR4729 piR-31162-210 NONHSAG022352.2 DHX40
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4729 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4729 Gene

Genomic Locations for MIR4729 Gene
chr17:59,366,083-59,366,154
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr17:57,443,444-57,443,515
(GRCh37/hg19)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR4729 Gene

Genes around MIR4729 on UCSC Golden Path with GeneCards custom track
MIR4729 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4729 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4729 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4729 Gene

Proteins for MIR4729 Gene

Post-translational modifications for MIR4729 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4729 Gene

Domains & Families for MIR4729 Gene

Gene Families for MIR4729 Gene

HGNC:
genes like me logo Genes that share domains with MIR4729: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4729 Gene

Function for MIR4729 Gene

Phenotypes From GWAS Catalog for MIR4729 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4729 Gene

Localization for MIR4729 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4729 Gene

Pathways & Interactions for MIR4729 Gene

PathCards logo

SuperPathways for MIR4729 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4729 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4729 Gene

Drugs & Compounds for MIR4729 Gene

No Compound Related Data Available

Transcripts for MIR4729 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4729 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B85E_9606 precursor_RNA 72 4

HGNC: 41585,

RefSeq: NR_039882,

Ensembl: ENST00000584140 (view in UCSC) ,

miRBase: MI0017366,

URS000024F41A_9606 miRNA 22 3

RefSeq: NR_039882,

miRBase: MIMAT0019851,

ENA: FR773015.1:1..22:ncRNA,

MIR4729 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4729 Gene

No ASD Table

Relevant External Links for MIR4729 Gene

GeneLoc Exon Structure for
MIR4729

No data available for mRNA/cDNA for MIR4729 Gene

Expression for MIR4729 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4729

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4729 Gene

Orthologs for MIR4729 Gene

Evolution for MIR4729 Gene

ENSEMBL:
Gene Tree for MIR4729 (if available)
TreeFam:
Gene Tree for MIR4729 (if available)

No data available for Orthologs for MIR4729 Gene

Paralogs for MIR4729 Gene

No data available for Paralogs for MIR4729 Gene

Variants for MIR4729 Gene

Additional dbSNP identifiers (rs#s) for MIR4729 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4729 Gene

Variant ID Type Subtype PubMed ID
esv3573764 CNV gain 25503493
nsv1057152 CNV gain 25217958
nsv1062736 CNV gain 25217958
nsv833500 CNV loss 17160897

Additional Variant Information for MIR4729 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4729

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4729 Gene

Disorders for MIR4729 Gene

No disorders were found for MIR4729 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4729 Gene

Publications for MIR4729 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4729 Gene

Sources for MIR4729 Gene