microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4729 Gene

Subcategory (RNA class) for MIR4729 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR4729 Gene

  • MicroRNA 4729 2 3 5
  • Hsa-Mir-4729 3
  • MIMAT0019851 53
  • MI0017366 53
  • MIR4729 2

External Ids for MIR4729 Gene

Previous GeneCards Identifiers for MIR4729 Gene

  • GC17U901637
  • GC17P057447

Summaries for MIR4729 Gene

Entrez Gene Summary for MIR4729 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4729 Gene

MIR4729 (MicroRNA 4729) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4729 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4729 Gene

Genomics for MIR4729 Gene

GeneHancer (GH) Regulatory Elements for MIR4729 Gene

Promoters and enhancers for MIR4729 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J059364 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.6 +4.0 3973 10.5 E2F8 ZBTB40 SREBF1 FOXA1 MLX RBPJ SMARCE1 NR2F1 NR2F6 ATF1 HEATR6 TUBD1 YPEL2 SMG8 RPS6KB1 DHX40 SKA2 MIR4729 piR-31162-210 NONHSAG022352.2
GH17J059386 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.3 +21.4 21432 2.6 TEAD4 CBFA2T2 TRIM24 EGR1 PKNOX1 HES1 EP300 MAFG RCOR1 ZFHX2 YPEL2 TEX14 piR-31162-210 MIR4729 NONHSAG022352.2
GH17J059377 Enhancer 0.6 ENCODE dbSUPER 0.4 +12.3 12275 2.7 FOXA1 FOXA2 MAZ RAD21 JUN YPEL2 DHX40 MIR4729 piR-31162-210 NONHSAG022352.2
GH17J059391 Enhancer 0.7 dbSUPER 0.3 +26.7 26727 1.7 CREB1 MIXL1 PPARG ZNF384 RXRB ATF7 SOX13 ZNF512B SAP130 FOXA2 piR-31162-210 piR-43099-259 piR-56022-231 piR-45504-240 piR-55281-272 DHX40 TEX14 MIR4729 YPEL2 NONHSAG022352.2
GH17J059375 Enhancer 0.4 ENCODE dbSUPER 0.4 +9.5 9549 0 MLLT1 YPEL2 MIR4729 piR-31162-210 NONHSAG022352.2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4729 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4729 Gene

Genomic Locations for MIR4729 Gene
chr17:59,366,083-59,366,154
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr17:57,443,444-57,443,515
(GRCh37/hg19)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR4729 Gene

Genes around MIR4729 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4729 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4729 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4729 Gene

Proteins for MIR4729 Gene

Post-translational modifications for MIR4729 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4729 Gene

Domains & Families for MIR4729 Gene

Gene Families for MIR4729 Gene

HGNC:
genes like me logo Genes that share domains with MIR4729: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4729 Gene

Function for MIR4729 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4729 Gene

Localization for MIR4729 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4729 Gene

Pathways & Interactions for MIR4729 Gene

PathCards logo

SuperPathways for MIR4729 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4729 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4729 Gene

Drugs & Compounds for MIR4729 Gene

No Compound Related Data Available

Transcripts for MIR4729 Gene

mRNA/cDNA for MIR4729 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :
(1) ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4729 Gene

No ASD Table

Relevant External Links for MIR4729 Gene

GeneLoc Exon Structure for
MIR4729
ECgene alternative splicing isoforms for
MIR4729

Expression for MIR4729 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4729 Gene:

MIR4729
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4729 Gene

Orthologs for MIR4729 Gene

Evolution for MIR4729 Gene

ENSEMBL:
Gene Tree for MIR4729 (if available)
TreeFam:
Gene Tree for MIR4729 (if available)

No data available for Orthologs for MIR4729 Gene

Paralogs for MIR4729 Gene

No data available for Paralogs for MIR4729 Gene

Variants for MIR4729 Gene

Sequence variations from dbSNP and Humsavar for MIR4729 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1002517298 -- 59,364,112(+) A/T upstream_transcript_variant
rs1002569349 -- 59,364,387(+) C/T upstream_transcript_variant
rs1003576582 -- 59,366,283(+) C/G downstream_transcript_variant
rs1004580527 -- 59,364,858(+) C/G upstream_transcript_variant
rs1005115400 -- 59,365,119(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4729 Gene

Variant ID Type Subtype PubMed ID
esv3573764 CNV gain 25503493
nsv1057152 CNV gain 25217958
nsv1062736 CNV gain 25217958
nsv833500 CNV loss 17160897

Additional Variant Information for MIR4729 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4729

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4729 Gene

Disorders for MIR4729 Gene

Additional Disease Information for MIR4729

No disorders were found for MIR4729 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4729 Gene

Publications for MIR4729 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR4729 Gene

Sources for MIR4729 Gene