microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4726 Gene

Subcategory (RNA class) for MIR4726 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR4726 Gene

  • MicroRNA 4726 2 3 5
  • Hsa-MiR-4726-3p 163 173
  • Hsa-Mir-4726 2 3
  • MIR4726 2 5
  • MIMAT0019846 50
  • MIMAT0019845 50
  • MI0017363 50

External Ids for MIR4726 Gene

Previous GeneCards Identifiers for MIR4726 Gene

  • GC17U901656
  • GC17P036881

Summaries for MIR4726 Gene

Entrez Gene Summary for MIR4726 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4726 Gene

MIR4726 (MicroRNA 4726) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4726 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4726 Gene

Genomics for MIR4726 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4726 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J038718 Promoter/Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas 600.7 -0.5 -459 1.7 ZNF692 RBFOX2 PKNOX1 PATZ1 REST SP1 POLR2A EZH2 ZNF600 SCRT2 ENSG00000275665 LOC105371762 MIR4726 PCGF2 PSMB3 piR-50444-176 CISD3 MLLT6
GH17J038720 Promoter/Enhancer 1 Ensembl ENCODE 600.7 +0.6 584 0.3 RBFOX2 EZH2 SCRT2 ZBTB44 CTBP1 HES1 SCRT1 NFIC KLF8 NR2F1 ENSG00000275665 LOC105371762 MIR4726 PSMB3 CISD3 MLLT6
GH17J038721 Enhancer 0.6 ENCODE 600.7 +0.4 422 0 RBFOX2 EZH2 SCRT2 CTBP1 HES1 SCRT1 NFIC KLF8 NR2F1 NR2F6 ENSG00000275665 LOC105371762 MIR4726 PSMB3 CISD3 MLLT6
GH17J038715 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.7 -3.8 -3790 1 RBFOX2 POLR2A ZNF513 PAF1 EGR2 SP1 EGR1 piR-50444-176 PCGF2 PSMB3 ENSG00000275665 MIR4726 CISD3 MLLT6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4726 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4726 Gene

Genomic Locations for MIR4726 Gene
chr17:38,719,691-38,719,748
(GRCh38/hg38)
Size:
58 bases
Orientation:
Plus strand
chr17:36,875,944-36,876,001
(GRCh37/hg19)
Size:
58 bases
Orientation:
Plus strand

Genomic View for MIR4726 Gene

Genes around MIR4726 on UCSC Golden Path with GeneCards custom track
MIR4726 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4726 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4726 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4726 Gene

Proteins for MIR4726 Gene

Post-translational modifications for MIR4726 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4726 Gene

Domains & Families for MIR4726 Gene

Gene Families for MIR4726 Gene

HGNC:
genes like me logo Genes that share domains with MIR4726: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4726 Gene

Function for MIR4726 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4726 Gene

Localization for MIR4726 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4726 Gene

Pathways & Interactions for MIR4726 Gene

PathCards logo

SuperPathways for MIR4726 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4726 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4726 Gene

Drugs & Compounds for MIR4726 Gene

No Compound Related Data Available

Transcripts for MIR4726 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4726 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000528E50_9606 miRNA 22 5

RefSeq: NR_039879,

LncBase: hsa-miR-4726-3p,

miRBase: MIMAT0019846,

TarBase: hsa-miR-4726-3p,

ENA: FR773009.1:1..22:ncRNA,

URS000075BEDC_9606 precursor_RNA 58 4

HGNC: 41722,

RefSeq: NR_039879,

Ensembl: ENST00000615971 (view in UCSC) ,

miRBase: MI0017363,

URS0000026924_9606 miRNA 23 3

RefSeq: NR_039879,

miRBase: MIMAT0019845,

ENA: FR773010.1:1..23:ncRNA,

MIR4726 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4726 Gene

No ASD Table

Relevant External Links for MIR4726 Gene

GeneLoc Exon Structure for
MIR4726

No data available for mRNA/cDNA for MIR4726 Gene

Expression for MIR4726 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4726 Gene

genes like me logo Genes that share expression patterns with MIR4726: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4726 Gene

Orthologs for MIR4726 Gene

Evolution for MIR4726 Gene

ENSEMBL:
Gene Tree for MIR4726 (if available)
TreeFam:
Gene Tree for MIR4726 (if available)

No data available for Orthologs for MIR4726 Gene

Paralogs for MIR4726 Gene

No data available for Paralogs for MIR4726 Gene

Variants for MIR4726 Gene

Additional dbSNP identifiers (rs#s) for MIR4726 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4726 Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv470585 CNV loss 18288195
nsv833438 CNV loss 17160897
nsv953894 CNV deletion 24416366

Additional Variant Information for MIR4726 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4726

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4726 Gene

Disorders for MIR4726 Gene

Additional Disease Information for MIR4726

No disorders were found for MIR4726 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4726 Gene

Publications for MIR4726 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4726 Gene

Sources for MIR4726 Gene