microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4722 Gene

Data sources for MIR4722 Gene:

RNA type for MIR4722 Gene

miRNA

Aliases for MIR4722 Gene

External Ids for MIR4722 Gene

Previous GeneCards Identifiers for MIR4722 Gene

  • GC16U901342
  • GC16M088786

Summaries for MIR4722 Gene

Entrez Gene Summary for MIR4722 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4722 Gene

MIR4722 (MicroRNA 4722) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4722 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4722 Gene

Genomics for MIR4722 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4722 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J088718 Enhancer 0.3 ENCODE 250.7 -2.0 -1961 0.1 POLR2A HIC1 ENSG00000260121 MIR4722 CTU2 PIEZO1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4722 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4722 Gene

Latest Assembly
chr16:88,716,278-88,716,337
(GRCh38/hg38)
Size:
60 bases
Orientation:
Minus strand

Previous Assembly
chr16:88,782,686-88,782,745
(GRCh37/hg19 by Entrez Gene)
Size:
60 bases
Orientation:
Minus strand

Genomic View for MIR4722 Gene

Genes around MIR4722 on UCSC Golden Path with GeneCards custom track
MIR4722 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4722 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4722 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4722 Gene

Proteins for MIR4722 Gene

Post-translational modifications for MIR4722 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4722 Gene

Domains & Families for MIR4722 Gene

Gene Families for MIR4722 Gene

HGNC:
genes like me logo Genes that share domains with MIR4722: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4722 Gene

Function for MIR4722 Gene

Phenotypes From GWAS Catalog for MIR4722 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4722 Gene

Localization for MIR4722 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4722 Gene

Pathways & Interactions for MIR4722 Gene

PathCards logo

SuperPathways for MIR4722 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4722 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4722 Gene

Drugs & Compounds for MIR4722 Gene

No Compound Related Data Available

Transcripts for MIR4722 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4722 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075BF79_9606 precursor_RNA 60 3

RefSeq: NR_039873,

Ensembl: ENST00000578292 (view in UCSC) ,

miRBase: MI0017357,

URS000047996E_9606 miRNA 23 3

RefSeq: NR_039873,

miRBase: MIMAT0019836,

ENA: FR773002.1:1..23:ncRNA,

URS000041A3B2_9606 miRNA 22 3

RefSeq: NR_039873,

miRBase: MIMAT0019837,

ENA: FR773001.1:1..22:ncRNA,

MIR4722 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4722 Gene

No ASD Table

Relevant External Links for MIR4722 Gene

GeneLoc Exon Structure for
MIR4722

No data available for mRNA/cDNA for MIR4722 Gene

Expression for MIR4722 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4722 Gene

genes like me logo Genes that share expression patterns with MIR4722: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4722 Gene

Orthologs for MIR4722 Gene

Evolution for MIR4722 Gene

ENSEMBL:
Gene Tree for MIR4722 (if available)
TreeFam:
Gene Tree for MIR4722 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4722

No data available for Orthologs for MIR4722 Gene

Paralogs for MIR4722 Gene

No data available for Paralogs for MIR4722 Gene

Variants for MIR4722 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4722 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4722 Gene

Variant ID Type Subtype PubMed ID
dgv3064n100 CNV gain 25217958
dgv3065n100 CNV gain 25217958
nsv1061256 CNV gain 25217958
nsv1063024 CNV gain 25217958
nsv1065973 CNV loss 25217958
nsv1160442 CNV deletion 26073780
nsv1927 CNV insertion 18451855
nsv471113 CNV loss 18288195
nsv471114 CNV gain 18288195
nsv482951 CNV loss 15286789
nsv517643 CNV loss 19592680
nsv833327 CNV loss 17160897
nsv952070 CNV deletion 24416366

Additional Variant Information for MIR4722 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4722
Leiden Open Variation Database (LOVD)
MIR4722

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4722 Gene

Disorders for MIR4722 Gene

Additional Disease Information for MIR4722

No disorders were found for MIR4722 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4722 Gene

Publications for MIR4722 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4722 Gene

Sources for MIR4722 Gene