microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4720 Gene

Data sources for MIR4720 Gene:

Subcategory (RNA class) for MIR4720 Gene

miRNA

Aliases for MIR4720 Gene

External Ids for MIR4720 Gene

Previous GeneCards Identifiers for MIR4720 Gene

  • GC16U901346
  • GC16P081416
  • GC16P081419
  • GC16P081386
  • GC16P081387
  • GC16P081388
  • GC16P081390
  • GC16P081314

Summaries for MIR4720 Gene

Entrez Gene Summary for MIR4720 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4720 Gene

MIR4720 (MicroRNA 4720) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.

Additional gene information for MIR4720 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4720 Gene

Genomics for MIR4720 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4720 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J081384 Enhancer 0.3 Ensembl ENCODE 250.7 -0.3 -317 4.6 AC092139.1 MIR4720 CMIP GAN
GH16J081400 Enhancer 0.8 Ensembl ENCODE 0.4 +16.5 16481 2.2 IKZF1 ELF1 ZNF341 NRF1 HDAC2 POLR2A CREM CREB1 CHD4 ATF1 piR-38051-122 MIR4720 CMIP GAN
GH16J081395 Enhancer 0.3 Ensembl ENCODE 0.4 +10.6 10582 1.6 CMIP piR-38051-122 MIR4720 GAN
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4720 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4720 Gene

Latest Assembly
chr16:81,385,018-81,385,093
(GRCh38/hg38)
Size:
76 bases
Orientation:
Plus strand

Previous Assembly
chr16:81,418,623-81,418,698
(GRCh37/hg19 by Entrez Gene)
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR4720 Gene

Genes around MIR4720 on UCSC Golden Path with GeneCards custom track
MIR4720 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4720 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4720 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4720 Gene

Proteins for MIR4720 Gene

Post-translational modifications for MIR4720 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4720 Gene

Domains & Families for MIR4720 Gene

Gene Families for MIR4720 Gene

HGNC:
genes like me logo Genes that share domains with MIR4720: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4720 Gene

Function for MIR4720 Gene

Phenotypes From GWAS Catalog for MIR4720 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4720 Gene

Localization for MIR4720 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4720 Gene

Pathways & Interactions for MIR4720 Gene

genes like me logo Genes that share pathways with MIR4720: view

Gene Ontology (GO) - Biological Process for MIR4720 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR4720 Gene

Drugs & Compounds for MIR4720 Gene

No Compound Related Data Available

Transcripts for MIR4720 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4720 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B68E_9606 precursor_RNA 76 3

RefSeq: NR_039871,

Ensembl: ENST00000581455 (view in UCSC) ,

miRBase: MI0017355,

URS00000DE8FA_9606 miRNA 22 3

RefSeq: NR_039871,

miRBase: MIMAT0019833,

ENA: FR772999.1:1..22:ncRNA,

URS000039B339_9606 miRNA 21 3

RefSeq: NR_039871,

miRBase: MIMAT0019834,

ENA: FR772998.1:1..21:ncRNA,

MIR4720 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4720 Gene

No ASD Table

Relevant External Links for MIR4720 Gene

GeneLoc Exon Structure for
MIR4720

No data available for mRNA/cDNA for MIR4720 Gene

Expression for MIR4720 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4720 Gene

Orthologs for MIR4720 Gene

Evolution for MIR4720 Gene

ENSEMBL:
Gene Tree for MIR4720 (if available)
TreeFam:
Gene Tree for MIR4720 (if available)

No data available for Orthologs for MIR4720 Gene

Paralogs for MIR4720 Gene

No data available for Paralogs for MIR4720 Gene

Variants for MIR4720 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4720 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4720 Gene

Variant ID Type Subtype PubMed ID
esv3639330 CNV loss 21293372
esv3639331 CNV loss 21293372

Additional Variant Information for MIR4720 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4720

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4720 Gene

Disorders for MIR4720 Gene

Additional Disease Information for MIR4720

No disorders were found for MIR4720 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4720 Gene

Publications for MIR4720 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4720 Gene

Sources for MIR4720 Gene