microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4718 Gene

Subcategory (RNA class) for MIR4718 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4718 Gene

  • MicroRNA 4718 2 3 5
  • Hsa-Mir-4718 2 3
  • MIR4718 2 5
  • MIMAT0019831 50
  • MI0017353 50

External Ids for MIR4718 Gene

Previous GeneCards Identifiers for MIR4718 Gene

  • GC16U901345
  • GC16P012816

Summaries for MIR4718 Gene

Entrez Gene Summary for MIR4718 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4718 Gene

MIR4718 (MicroRNA 4718) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4718 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4718 Gene

Genomics for MIR4718 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4718 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J012723 Enhancer 0.2 Ensembl 0.7 +3.6 3573 0.6 piR-51671-018 CPPED1 ENSG00000238685 ENSG00000261158 MIR4718 SNX29
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4718 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4718 Gene

Genomic Locations for MIR4718 Gene
chr16:12,720,321-12,720,371
(GRCh38/hg38)
Size:
51 bases
Orientation:
Plus strand
chr16:12,814,178-12,814,228
(GRCh37/hg19)
Size:
51 bases
Orientation:
Plus strand

Genomic View for MIR4718 Gene

Genes around MIR4718 on UCSC Golden Path with GeneCards custom track
MIR4718 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4718 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4718 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4718 Gene

Proteins for MIR4718 Gene

Post-translational modifications for MIR4718 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4718 Gene

Domains & Families for MIR4718 Gene

Gene Families for MIR4718 Gene

HGNC:
genes like me logo Genes that share domains with MIR4718: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4718 Gene

Function for MIR4718 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4718 Gene

Localization for MIR4718 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4718 Gene

Pathways & Interactions for MIR4718 Gene

PathCards logo

SuperPathways for MIR4718 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4718 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4718 Gene

Drugs & Compounds for MIR4718 Gene

No Compound Related Data Available

Transcripts for MIR4718 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4718 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A6BF_9606 precursor_RNA 51 4

HGNC: 41900,

RefSeq: NR_039869,

Ensembl: ENST00000580978 (view in UCSC) ,

miRBase: MI0017353,

URS00000E8004_9606 miRNA 21 3

RefSeq: NR_039869,

miRBase: MIMAT0019831,

ENA: FR772996.1:1..21:ncRNA,

MIR4718 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4718 Gene

No ASD Table

Relevant External Links for MIR4718 Gene

GeneLoc Exon Structure for
MIR4718

No data available for mRNA/cDNA for MIR4718 Gene

Expression for MIR4718 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4718 Gene

Orthologs for MIR4718 Gene

Evolution for MIR4718 Gene

ENSEMBL:
Gene Tree for MIR4718 (if available)
TreeFam:
Gene Tree for MIR4718 (if available)

No data available for Orthologs for MIR4718 Gene

Paralogs for MIR4718 Gene

No data available for Paralogs for MIR4718 Gene

Variants for MIR4718 Gene

Additional dbSNP identifiers (rs#s) for MIR4718 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4718 Gene

Variant ID Type Subtype PubMed ID
nsv1052802 CNV loss 25217958
nsv1053617 CNV loss 25217958

Additional Variant Information for MIR4718 Gene

Human Gene Mutation Database (HGMD)
MIR4718
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4718

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4718 Gene

Disorders for MIR4718 Gene

Additional Disease Information for MIR4718

No disorders were found for MIR4718 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4718 Gene

Publications for MIR4718 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4718 Gene

Sources for MIR4718 Gene