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MIR4718 Gene(RNA Gene)

MicroRNA 4718

GCID:
GC16P012720
GIFtS:
12
Genes Participants
UDN Logo

Aliases for MIR4718 Gene

Subcategory (RNA class) for MIR4718 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4718 Gene

  • MicroRNA 4718 2 3 5
  • Hsa-Mir-4718 3

External Ids for MIR4718 Gene

Previous GeneCards Identifiers for MIR4718 Gene

  • GC16U901345
  • GC16P012816

Summaries for MIR4718 Gene

Entrez Gene Summary for MIR4718 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4718 Gene

MIR4718 (MicroRNA 4718) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4718 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4718 Gene

Genomics for MIR4718 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR4718 Gene

Promoters and enhancers for MIR4718 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH16I012674 Enhancer 1 FANTOM5 ENCODE 0.3 -44.9 -44855 2.5 BCOR MEIS2 TEAD4 TAL1 JUN BATF FOSL1 TCF12 NCOR1 CBFA2T2 CPPED1 LOC105371088 MIR4718
GH16I012661 Enhancer 0.9 ENCODE 0.2 -58.4 -58412 0.1 MLX ZFP64 ARID4B SIN3A ZNF48 SLC30A9 ZNF143 SP5 NFYC MXD4 LOC105371088 MIR4718 CPPED1
GH16I012728 Enhancer 0.3 ENCODE 0.4 +9.3 9307 1.7 JUN CPPED1 ENSG00000238685 MIR4718 LOC105371090
GH16I012679 Enhancer 0.4 ENCODE 0.3 -40.8 -40800 0.1 ZGPAT ZNF792 TCF7L2 LOC105371088 MIR4718 CPPED1
GH16I012681 Enhancer 0.3 ENCODE 0.3 -40.4 -40432 0.2 ZNF530 LOC105371088 MIR4718 CPPED1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4718 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4718 Gene

Genomic Locations for MIR4718 Gene
chr16:12,720,321-12,720,371
(GRCh38/hg38)
Size:
51 bases
Orientation:
Plus strand
chr16:12,814,178-12,814,228
(GRCh37/hg19)

Genomic View for MIR4718 Gene

Genes around MIR4718 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4718 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4718 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4718 Gene

Proteins for MIR4718 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4718 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4718 Gene

Domains & Families for MIR4718 Gene

Gene Families for MIR4718 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4718: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4718 Gene

Function for MIR4718 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4718 Gene

Localization for MIR4718 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4718 Gene

Pathways & Interactions for MIR4718 Gene

SuperPathways for MIR4718 Gene

PathCards logo More details on SuperPathways for MIR4718
No Data Available

Interacting Proteins for MIR4718 Gene

Gene Ontology (GO) - Biological Process for MIR4718 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4718 Gene

Drugs & Compounds for MIR4718 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4718 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4718 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4718 Gene

No ASD Table

Relevant External Links for MIR4718 Gene

GeneLoc Exon Structure for
MIR4718
ECgene alternative splicing isoforms for
MIR4718

Expression for MIR4718 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of MIR4718 Gene:

MIR4718
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4718 Gene

Orthologs for MIR4718 Gene

Evolution for MIR4718 Gene

ENSEMBL:
Gene Tree for MIR4718 (if available)
TreeFam:
Gene Tree for MIR4718 (if available)

No data available for Orthologs for MIR4718 Gene

Paralogs for MIR4718 Gene

No data available for Paralogs for MIR4718 Gene

Variants for MIR4718 Gene

Sequence variations from dbSNP and Humsavar for MIR4718 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000639886 -- 12,719,594(+) T/C upstream_transcript_variant
rs1000706545 -- 12,720,655(+) T/C downstream_transcript_variant
rs1001075104 -- 12,719,365(+) T/C upstream_transcript_variant
rs1001182896 -- 12,720,391(+) G/A/T downstream_transcript_variant
rs1003817295 -- 12,718,696(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4718 Gene

Variant ID Type Subtype PubMed ID
nsv1053617 CNV loss 25217958
nsv1052802 CNV loss 25217958

Additional Variant Information for MIR4718 Gene

Human Gene Mutation Database (HGMD)
MIR4718
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4718

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4718 Gene

Disorders for MIR4718 Gene

Additional Disease Information for MIR4718

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4718 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4718 Gene

Publications for MIR4718 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4718 Gene

Sources for MIR4718 Gene

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