microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4700 Gene

Subcategory (RNA class) for MIR4700 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4700 Gene

  • MicroRNA 4700 2 3 5
  • Hsa-Mir-4700 2 3
  • MIR4700 2 5
  • MIMAT0019796 50
  • MIMAT0019797 50
  • MI0017333 50
  • Mir-4700 3

External Ids for MIR4700 Gene

Previous GeneCards Identifiers for MIR4700 Gene

  • GC12U901590
  • GC12P121196
  • GC12P121211
  • GC12P121223
  • GC12P120711

Summaries for MIR4700 Gene

Entrez Gene Summary for MIR4700 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4700 Gene

MIR4700 (MicroRNA 4700) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Organelle biogenesis and maintenance and Cargo trafficking to the periciliary membrane.

Additional gene information for MIR4700 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4700 Gene

Genomics for MIR4700 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4700 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J120721 Enhancer 0.7 Ensembl ENCODE dbSUPER 600.7 -1.0 -1026 0.5 RCOR1 CHD2 GATA2 ENSG00000256569 MIR4700 piR-35793 piR-32711 piR-38679 piR-37130 piR-38949 piR-39430 piR-34193 piR-34329
GH12J120723 Enhancer 0.6 Ensembl dbSUPER 600.7 -0.3 -292 0.2 CEBPG ZNF600 CEBPB ENSG00000256569 MIR4700 piR-35793 piR-32711 piR-38679 piR-37130 piR-39430 piR-34193 piR-34329 piR-34332
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4700 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4700 Gene

Genomic Locations for MIR4700 Gene
chr12:120,723,193-120,723,266
(GRCh38/hg38)
Size:
74 bases
Orientation:
Plus strand
chr12:121,160,996-121,161,069
(GRCh37/hg19)
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR4700 Gene

Genes around MIR4700 on UCSC Golden Path with GeneCards custom track
MIR4700 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4700 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4700 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4700 Gene

Proteins for MIR4700 Gene

Post-translational modifications for MIR4700 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4700 Gene

Domains & Families for MIR4700 Gene

Gene Families for MIR4700 Gene

HGNC:
genes like me logo Genes that share domains with MIR4700: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4700 Gene

Function for MIR4700 Gene

Phenotypes From GWAS Catalog for MIR4700 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4700 Gene

Localization for MIR4700 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4700 Gene

Pathways & Interactions for MIR4700 Gene

genes like me logo Genes that share pathways with MIR4700: view

Gene Ontology (GO) - Biological Process for MIR4700 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR4700 Gene

Drugs & Compounds for MIR4700 Gene

No Compound Related Data Available

Transcripts for MIR4700 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4700 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B578_9606 precursor_RNA 74 5

HGNC: 41806,

RefSeq: NR_039849,

Ensembl: ENST00000578311 (view in UCSC) ,

miRBase: MI0017333,

ENA: LM611384.1:1..74:precursor_RNA,

URS00003840E5_9606 miRNA 26 3

RefSeq: NR_039849,

miRBase: MIMAT0019797,

ENA: FR772964.1:1..26:ncRNA, LM611384.1:41..66:ncRNA,

URS0000334286_9606 miRNA 22 3

RefSeq: NR_039849,

miRBase: MIMAT0019796,

ENA: FR772965.1:1..22:ncRNA, LM382554.1:1..22:ncRNA, LM611384.1:10..31:ncRNA,

MIR4700 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR4700 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4700 Gene

No ASD Table

Relevant External Links for MIR4700 Gene

GeneLoc Exon Structure for
MIR4700

Expression for MIR4700 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4700 Gene

genes like me logo Genes that share expression patterns with MIR4700: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4700 Gene

Orthologs for MIR4700 Gene

Evolution for MIR4700 Gene

ENSEMBL:
Gene Tree for MIR4700 (if available)
TreeFam:
Gene Tree for MIR4700 (if available)

No data available for Orthologs for MIR4700 Gene

Paralogs for MIR4700 Gene

No data available for Paralogs for MIR4700 Gene

Variants for MIR4700 Gene

Additional dbSNP identifiers (rs#s) for MIR4700 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4700 Gene

Variant ID Type Subtype PubMed ID
nsv521928 CNV gain 19592680

Additional Variant Information for MIR4700 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4700

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4700 Gene

Disorders for MIR4700 Gene

Additional Disease Information for MIR4700

No disorders were found for MIR4700 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4700 Gene

Publications for MIR4700 Gene

  1. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin SY … Soranzo N (Nature genetics 2014) 3
  2. Human metabolic individuality in biomedical and pharmaceutical research. (PMID: 21886157) Suhre K … Gieger C (Nature 2011) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4700 Gene

Sources for MIR4700 Gene