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Aliases for MIR4695 Gene

Subcategory (RNA class) for MIR4695 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4695 Gene

  • MicroRNA 4695 2 3 5
  • Hsa-Mir-4695 3

External Ids for MIR4695 Gene

Previous GeneCards Identifiers for MIR4695 Gene

  • GC01U903263
  • GC01M019212

Summaries for MIR4695 Gene

Entrez Gene Summary for MIR4695 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4695 Gene

MIR4695 (MicroRNA 4695) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4695 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4695 Gene

Genomics for MIR4695 Gene

GeneHancer (GH) Regulatory Elements for MIR4695 Gene

Promoters and enhancers for MIR4695 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I018884 Enhancer 0.7 ENCODE 550.8 -1.0 -1037 0.2 HDGF CTCF RB1 SAP130 TEAD4 ARID4B RAD21 TEAD3 CC2D1A ZNF335 MIR4695 MIR1290 ALDH4A1 ENSG00000255275
GH01I018890 Promoter/Enhancer 1.3 EPDnew ENCODE 0.4 -8.7 -8724 3.1 HDAC1 HDGF GATA2 EGR1 SMARCA5 ELF1 ZEB2 ZNF148 IKZF1 NR2C1 ALDH4A1 TAS1R2 MIR4695 MIR1290 ENSG00000255275
GH01I018894 Enhancer 0.7 dbSUPER 0.4 -11.6 -11644 1.1 TFAP4 TFE3 RXRA SAP130 NR2F1 CBFA2T3 NR2F2 RARA ZNF121 TCF12 ALDH4A1 MIR1290 MIR4695 ENSG00000255275
GH01I018885 Enhancer 0.2 ENCODE 0.8 -3.0 -2971 1.2 TAS1R2 ALDH4A1 MIR4695 MIR1290 ENSG00000255275
GH01I018893 Enhancer 0.2 ENCODE 0.4 -10.6 -10638 0 MIR1290 ALDH4A1 MIR4695 ENSG00000255275
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4695 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4695 Gene

Genomic Locations for MIR4695 Gene
chr1:18,883,202-18,883,275
(GRCh38/hg38)
Size:
74 bases
Orientation:
Minus strand
chr1:19,209,688-19,209,774
(GRCh37/hg19)

Genomic View for MIR4695 Gene

Genes around MIR4695 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4695 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4695 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4695 Gene

ORGUL Member Location for MIR4695 Gene

ORGUL Member Location for MIR4695 gene

Proteins for MIR4695 Gene

Post-translational modifications for MIR4695 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4695 Gene

Domains & Families for MIR4695 Gene

Gene Families for MIR4695 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4695: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4695 Gene

Function for MIR4695 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4695 Gene

Localization for MIR4695 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4695 Gene

Pathways & Interactions for MIR4695 Gene

SuperPathways for MIR4695 Gene

No Data Available

Interacting Proteins for MIR4695 Gene

Gene Ontology (GO) - Biological Process for MIR4695 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4695 Gene

Drugs & Compounds for MIR4695 Gene

No Compound Related Data Available

Transcripts for MIR4695 Gene

mRNA/cDNA for MIR4695 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4695 Gene

No ASD Table

Relevant External Links for MIR4695 Gene

GeneLoc Exon Structure for
MIR4695
ECgene alternative splicing isoforms for
MIR4695

Expression for MIR4695 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4695 Gene:

MIR4695
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4695 Gene

Orthologs for MIR4695 Gene

Evolution for MIR4695 Gene

ENSEMBL:
Gene Tree for MIR4695 (if available)
TreeFam:
Gene Tree for MIR4695 (if available)

No data available for Orthologs for MIR4695 Gene

Paralogs for MIR4695 Gene

No data available for Paralogs for MIR4695 Gene

Variants for MIR4695 Gene

Sequence variations from dbSNP and Humsavar for MIR4695 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs138788183 uncertain-significance, likely-benign, Hyperprolinemia, Deficiency of pyrroline-5-carboxylate reductase 18,883,121(-) C/T downstream_transcript_variant
rs139340058 uncertain-significance, Hyperprolinemia 18,883,154(-) G/A downstream_transcript_variant
rs369957092 uncertain-significance, Hyperprolinemia 18,883,392(-) C/G upstream_transcript_variant
rs72936434 uncertain-significance, Hyperprolinemia 18,883,298(-) G/A upstream_transcript_variant
rs1005204076 -- 18,883,646(-) C/T upstream_transcript_variant

Additional Variant Information for MIR4695 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4695

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4695 Gene

Disorders for MIR4695 Gene

Additional Disease Information for MIR4695

No disorders were found for MIR4695 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4695 Gene

Publications for MIR4695 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4695 Gene

Sources for MIR4695 Gene

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