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Aliases for MIR4691 Gene

Subcategory (RNA class) for MIR4691 Gene


Quality Score for this RNA gene is


Aliases for MIR4691 Gene

  • MicroRNA 4691 2 3 5
  • Hsa-Mir-4691 3
  • Mir-4691 3

External Ids for MIR4691 Gene

Previous GeneCards Identifiers for MIR4691 Gene

  • GC11U901856
  • GC11P067805
  • GC11P067814

Summaries for MIR4691 Gene

Entrez Gene Summary for MIR4691 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4691 Gene

MIR4691 (MicroRNA 4691) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Metabolism.

Additional gene information for MIR4691 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4691 Gene

Genomics for MIR4691 Gene

GeneHancer (GH) Regulatory Elements for MIR4691 Gene

Promoters and enhancers for MIR4691 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I068026 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.8 -3.4 -3412 7.6 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 POLR2B LOC105369361 NDUFS8 ALDH3B1 PPP6R3 IGHMBP2 KDM2A LOC105369362 TCIRG1 MIR4691 MIR7113
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4691 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4691 Gene

Genomic Locations for MIR4691 Gene
85 bases
Plus strand

Genomic View for MIR4691 Gene

Genes around MIR4691 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4691 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4691 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4691 Gene

Proteins for MIR4691 Gene

Post-translational modifications for MIR4691 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4691 Gene

Domains & Families for MIR4691 Gene

Gene Families for MIR4691 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4691: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4691 Gene

Function for MIR4691 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4691 Gene

Localization for MIR4691 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4691 Gene

Drugs & Compounds for MIR4691 Gene

No Compound Related Data Available

Transcripts for MIR4691 Gene

mRNA/cDNA for MIR4691 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4691 Gene

No ASD Table

Relevant External Links for MIR4691 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4691 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4691 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4691 Gene:

genes like me logo Genes that share expression patterns with MIR4691: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4691 Gene

Orthologs for MIR4691 Gene

Evolution for MIR4691 Gene

Gene Tree for MIR4691 (if available)
Gene Tree for MIR4691 (if available)

No data available for Orthologs for MIR4691 Gene

Paralogs for MIR4691 Gene

No data available for Paralogs for MIR4691 Gene

Variants for MIR4691 Gene

Sequence variations from dbSNP and Humsavar for MIR4691 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs121912638 pathogenic, uncertain-significance, Mitochondrial complex I deficiency, not provided 68,033,216(+) G/A upstream_transcript_variant
rs121912639 pathogenic, Mitochondrial complex I deficiency 68,033,165(+) C/T upstream_transcript_variant
rs146766138 pathogenic, uncertain-significance, Mitochondrial complex I deficiency, not specified 68,033,140(+) C/G/T upstream_transcript_variant
rs28939679 pathogenic, likely-pathogenic, Mitochondrial complex I deficiency, not provided 68,033,147(+) C/T upstream_transcript_variant
rs3115545 likely-benign, benign, not specified, Leigh syndrome, Mitochondrial complex I deficiency 68,033,027(+) T/A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4691 Gene

Variant ID Type Subtype PubMed ID
dgv1221n100 CNV gain 25217958
dgv1981n54 CNV gain 21841781
dgv1983n54 CNV loss 21841781
esv2759835 CNV gain+loss 17122850
nsv468606 CNV gain 19166990
nsv468615 CNV loss 19166990
nsv469856 CNV gain 16826518
nsv469964 CNV loss 18288195
nsv555278 CNV loss 21841781
nsv555282 CNV loss 21841781
nsv825963 CNV gain 20364138
nsv8836 CNV gain 18304495
nsv951026 CNV deletion 24416366

Additional Variant Information for MIR4691 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4691 Gene

Disorders for MIR4691 Gene

Additional Disease Information for MIR4691

No disorders were found for MIR4691 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4691 Gene

Publications for MIR4691 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4691 Gene

Sources for MIR4691 Gene

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