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Aliases for MIR4684 Gene

Subcategory (RNA class) for MIR4684 Gene


Quality Score for this RNA gene is


Aliases for MIR4684 Gene

  • MicroRNA 4684 2 3 5
  • Hsa-Mir-4684 3

External Ids for MIR4684 Gene

Previous GeneCards Identifiers for MIR4684 Gene

  • GC01U903289
  • GC01P023049

Summaries for MIR4684 Gene

Entrez Gene Summary for MIR4684 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4684 Gene

MIR4684 (MicroRNA 4684) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4684 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4684 Gene

Genomics for MIR4684 Gene

GeneHancer (GH) Regulatory Elements for MIR4684 Gene

Promoters and enhancers for MIR4684 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I022712 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 0.4 -8.5 -8535 1.6 MXI1 ARNT ZNF449 ZIC2 ZNF335 FOXM1 ZNF121 ZFHX2 GLIS2 POLR2A EPHB2 TCEA3 MIR4684
GH01I022716 Enhancer 0.6 dbSUPER 0.8 -2.1 -2099 1.9 FOXA2 NRF1 CBFA2T3 ZMYM3 FEZF1 ZIC2 GATA3 GLIS1 CBFA2T2 NFE2 ENSG00000225952 EPHB2 MIR4684
GH01I022749 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +31.1 31053 2.7 SIN3A ZBTB40 SCRT2 FOS ZBTB11 CEBPB REST ELF1 SP1 IKZF1 GC01P022751 EPHB2 MIR4684
GH01I022711 Enhancer 1 ENCODE dbSUPER 0.4 -7.0 -6976 1.2 ATF1 RB1 BATF IRF4 GLIS2 ATF7 ETV6 FOS BCLAF1 IKZF2 EPHB2 ENSG00000225952 KDM1A MIR4684
GH01I022745 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.3 +27.5 27473 2.8 FOXA2 SIN3A RAD21 YY1 GLIS2 FOS RXRA CEBPB REST ZEB2 EPHB2 GC01P022751 MIR4684
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4684 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4684 Gene

Genomic Locations for MIR4684 Gene
82 bases
Plus strand

Genomic View for MIR4684 Gene

Genes around MIR4684 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4684 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4684 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4684 Gene

Proteins for MIR4684 Gene

Post-translational modifications for MIR4684 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4684 Gene

Domains & Families for MIR4684 Gene

Gene Families for MIR4684 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4684: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4684 Gene

Function for MIR4684 Gene

Phenotypes From GWAS Catalog for MIR4684 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4684 Gene

Localization for MIR4684 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4684 Gene

Pathways & Interactions for MIR4684 Gene

SuperPathways for MIR4684 Gene

No Data Available

Interacting Proteins for MIR4684 Gene

Gene Ontology (GO) - Biological Process for MIR4684 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4684 Gene

Drugs & Compounds for MIR4684 Gene

No Compound Related Data Available

Transcripts for MIR4684 Gene

mRNA/cDNA for MIR4684 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4684 Gene

No ASD Table

Relevant External Links for MIR4684 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4684 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4684 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4684 Gene

Orthologs for MIR4684 Gene

Evolution for MIR4684 Gene

Gene Tree for MIR4684 (if available)
Gene Tree for MIR4684 (if available)

No data available for Orthologs for MIR4684 Gene

Paralogs for MIR4684 Gene

No data available for Paralogs for MIR4684 Gene

Variants for MIR4684 Gene

Sequence variations from dbSNP and Humsavar for MIR4684 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002650115 -- 22,718,995(+) A/T upstream_transcript_variant
rs1003104166 -- 22,718,308(+) A/C/G upstream_transcript_variant
rs1003118789 -- 22,719,738(+) G/A downstream_transcript_variant
rs1003729054 -- 22,717,925(+) G/A upstream_transcript_variant
rs1004373771 -- 22,718,314(+) CTTCTT/CTT upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4684 Gene

Variant ID Type Subtype PubMed ID
esv34161 CNV loss 18971310

Additional Variant Information for MIR4684 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4684 Gene

Disorders for MIR4684 Gene

Additional Disease Information for MIR4684

No disorders were found for MIR4684 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4684 Gene

Publications for MIR4684 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4684 Gene

Sources for MIR4684 Gene

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