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Aliases for MIR4683 Gene

Subcategory (RNA class) for MIR4683 Gene


Quality Score for this RNA gene is


Aliases for MIR4683 Gene

  • MicroRNA 4683 2 3 5
  • Hsa-Mir-4683 3

External Ids for MIR4683 Gene

Previous GeneCards Identifiers for MIR4683 Gene

  • GC10U901539
  • GC10M035934

Summaries for MIR4683 Gene

Entrez Gene Summary for MIR4683 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4683 Gene

MIR4683 (MicroRNA 4683) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Ectoderm Differentiation and Mesodermal Commitment Pathway.

Additional gene information for MIR4683 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4683 Gene

Genomics for MIR4683 Gene

GeneHancer (GH) Regulatory Elements for MIR4683 Gene

Promoters and enhancers for MIR4683 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I035639 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 550.8 -1.0 -978 5 PKNOX1 SIN3A FEZF1 ZNF2 YY1 ZNF213 ZNF143 SP3 NFYC REST FZD8 LOC105376494 PIR39028 MIR4683
GH10I035640 Promoter/Enhancer 0.9 Ensembl ENCODE 550.8 +1.9 1885 0.5 SP1 POU5F1 EZH2 PIR39028 MIR4683 FZD8 ENSG00000273312
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4683 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4683 Gene

Genomic Locations for MIR4683 Gene
81 bases
Minus strand

Genomic View for MIR4683 Gene

Genes around MIR4683 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4683 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4683 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4683 Gene

Proteins for MIR4683 Gene

Post-translational modifications for MIR4683 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4683 Gene

Domains & Families for MIR4683 Gene

Gene Families for MIR4683 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4683: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4683 Gene

Function for MIR4683 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4683 Gene

Localization for MIR4683 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4683 Gene

Drugs & Compounds for MIR4683 Gene

No Compound Related Data Available

Transcripts for MIR4683 Gene

mRNA/cDNA for MIR4683 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4683 Gene

No ASD Table

Relevant External Links for MIR4683 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4683 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4683 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4683 Gene:

genes like me logo Genes that share expression patterns with MIR4683: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4683 Gene

Orthologs for MIR4683 Gene

Evolution for MIR4683 Gene

Gene Tree for MIR4683 (if available)
Gene Tree for MIR4683 (if available)

No data available for Orthologs for MIR4683 Gene

Paralogs for MIR4683 Gene

No data available for Paralogs for MIR4683 Gene

Variants for MIR4683 Gene

Sequence variations from dbSNP and Humsavar for MIR4683 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000117060 -- 35,642,727(-) C/G upstream_transcript_variant
rs1000524802 -- 35,641,881(-) G/A upstream_transcript_variant
rs1000551106 -- 35,642,482(-) T/G upstream_transcript_variant
rs1001282277 -- 35,643,070(-) C/G upstream_transcript_variant
rs1001514046 -- 35,641,853(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4683 Gene

Variant ID Type Subtype PubMed ID
dgv1034n54 CNV loss 21841781
dgv1035n54 CNV loss 21841781
dgv1036n54 CNV loss 21841781
dgv144n67 CNV gain 20364138
esv22469 CNV loss 19812545
nsv466871 CNV loss 19166990
nsv521143 CNV loss 19592680
nsv550413 CNV loss 21841781
nsv550415 CNV loss 21841781
nsv550416 CNV gain 21841781
nsv825337 CNV gain 20364138
nsv825340 CNV gain 20364138
nsv825341 CNV gain 20364138

Additional Variant Information for MIR4683 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4683 Gene

Disorders for MIR4683 Gene

Additional Disease Information for MIR4683

No disorders were found for MIR4683 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4683 Gene

Publications for MIR4683 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4683 Gene

Sources for MIR4683 Gene

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