microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4676 Gene

Subcategory (RNA class) for MIR4676 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR4676 Gene

  • MicroRNA 4676 2 3 5
  • Hsa-MiR-4676-5p 166 177
  • Hsa-Mir-4676 3
  • MIMAT0019759 51
  • MIMAT0019758 51
  • MI0017307 51
  • MIR4676 2

External Ids for MIR4676 Gene

Previous GeneCards Identifiers for MIR4676 Gene

  • GC10U901543
  • GC10P074483

Summaries for MIR4676 Gene

Entrez Gene Summary for MIR4676 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4676 Gene

MIR4676 (MicroRNA 4676) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4676 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4676 Gene

Genomics for MIR4676 Gene

GeneHancer (GH) Regulatory Elements for MIR4676 Gene

Promoters and enhancers for MIR4676 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J072719 Enhancer 0.7 Ensembl ENCODE 500.7 -0.5 -452 2.4 CUX1 OSR2 POLR2A FOSL1 ZNF664 ATF4 ZNF398 SMARCA4 FOS ZNF692 MIR4676 ENSG00000226163 CFAP70 NUDT13 piR-50437-064 MCU
GH10J072728 Enhancer 0.9 Ensembl ENCODE 0.4 +8.4 8372 5.6 ZNF316 ZBTB17 MAFF GATA3 ZNF184 CEBPG MAFK ZFHX2 BATF JUND ENSG00000280166 DNAJB12 ENSG00000226163 OIT3 CFAP70 MIR4676 MCU
GH10J072712 Enhancer 0.8 Ensembl ENCODE 0.4 -8.4 -8428 2 ZNF316 NFIC MAFF MAFK ZBTB48 IKZF3 ZSCAN16 MAFG PRDM6 CEBPB piR-50437-064 DNAJB12 CFAP70 NUDT13 MIR4676 MCU
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4676 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4676 Gene

Genomic Locations for MIR4676 Gene
chr10:72,721,029-72,721,100
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr10:74,480,787-74,480,858
(GRCh37/hg19)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR4676 Gene

Genes around MIR4676 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4676 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4676 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4676 Gene

Proteins for MIR4676 Gene

Post-translational modifications for MIR4676 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4676 Gene

Domains & Families for MIR4676 Gene

Gene Families for MIR4676 Gene

HGNC:
genes like me logo Genes that share domains with MIR4676: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4676 Gene

Function for MIR4676 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4676 Gene

Localization for MIR4676 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4676 Gene

Pathways & Interactions for MIR4676 Gene

PathCards logo

SuperPathways for MIR4676 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4676 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4676 Gene

Drugs & Compounds for MIR4676 Gene

No Compound Related Data Available

Transcripts for MIR4676 Gene

mRNA/cDNA for MIR4676 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
2 ENA transcripts :
1 LncBase transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4676 Gene

No ASD Table

Relevant External Links for MIR4676 Gene

GeneLoc Exon Structure for
MIR4676

Expression for MIR4676 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4676 Gene

Orthologs for MIR4676 Gene

Evolution for MIR4676 Gene

ENSEMBL:
Gene Tree for MIR4676 (if available)
TreeFam:
Gene Tree for MIR4676 (if available)

No data available for Orthologs for MIR4676 Gene

Paralogs for MIR4676 Gene

No data available for Paralogs for MIR4676 Gene

Variants for MIR4676 Gene

Additional dbSNP identifiers (rs#s) for MIR4676 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4676 Gene

Variant ID Type Subtype PubMed ID
esv2759767 CNV gain 17122850

Additional Variant Information for MIR4676 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4676

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4676 Gene

Disorders for MIR4676 Gene

Additional Disease Information for MIR4676

No disorders were found for MIR4676 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4676 Gene

Publications for MIR4676 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4676 Gene

Sources for MIR4676 Gene