microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4675 Gene

Data sources for MIR4675 Gene:

RNA type for MIR4675 Gene

miRNA

Aliases for MIR4675 Gene

External Ids for MIR4675 Gene

Previous GeneCards Identifiers for MIR4675 Gene

  • GC10U901536
  • GC10P020843

Summaries for MIR4675 Gene

Entrez Gene Summary for MIR4675 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4675 Gene

MIR4675 (MicroRNA 4675) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4675 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4675 Gene

Genomics for MIR4675 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4675 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J020552 Enhancer 0.5 FANTOM5 Ensembl 250.7 +0.5 464 1.3 RFX1 MIR4675 piR-33605-036 lnc-PLXDC2-1 PLXDC2 NEBL
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4675 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4675 Gene

Latest Assembly
chr10:20,551,970-20,552,046
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand

Previous Assembly
chr10:20,840,899-20,840,975
(GRCh37/hg19 by Entrez Gene)
Size:
77 bases
Orientation:
Plus strand

chr10:20,840,899-20,840,975
(GRCh37/hg19 by Ensembl)
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR4675 Gene

Genes around MIR4675 on UCSC Golden Path with GeneCards custom track
MIR4675 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4675 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4675 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4675 Gene

Proteins for MIR4675 Gene

Post-translational modifications for MIR4675 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4675 Gene

Domains & Families for MIR4675 Gene

Gene Families for MIR4675 Gene

HGNC:
genes like me logo Genes that share domains with MIR4675: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4675 Gene

Function for MIR4675 Gene

Phenotypes From GWAS Catalog for MIR4675 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4675 Gene

Localization for MIR4675 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4675 Gene

Pathways & Interactions for MIR4675 Gene

PathCards logo

SuperPathways for MIR4675 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4675 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4675 Gene

Drugs & Compounds for MIR4675 Gene

No Compound Related Data Available

Transcripts for MIR4675 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4675 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075E335_9606 pre_miRNA 77 3

RefSeq: NR_039822,

Ensembl: ENST00000577898 (view in UCSC) ,

miRBase: MI0017306,

URS000012C8F2_9606 miRNA 22 3

RefSeq: NR_039822,

miRBase: MIMAT0019757,

ENA: FR772925.1:1..22:ncRNA,

MIR4675 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4675 Gene

No ASD Table

Relevant External Links for MIR4675 Gene

GeneLoc Exon Structure for
MIR4675

No data available for mRNA/cDNA for MIR4675 Gene

Expression for MIR4675 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4675 Gene

genes like me logo Genes that share expression patterns with MIR4675: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4675 Gene

Orthologs for MIR4675 Gene

Evolution for MIR4675 Gene

ENSEMBL:
Gene Tree for MIR4675 (if available)
TreeFam:
Gene Tree for MIR4675 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4675

No data available for Orthologs for MIR4675 Gene

Paralogs for MIR4675 Gene

No data available for Paralogs for MIR4675 Gene

Variants for MIR4675 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4675 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4675 Gene

Variant ID Type Subtype PubMed ID
dgv72n27 CNV loss 19166990
dgv992n54 CNV loss 21841781
dgv993n54 CNV loss 21841781
esv2759739 CNV gain+loss 17122850
esv34621 CNV loss 17911159
esv3622559 CNV loss 21293372
esv3622560 CNV loss 21293372
nsv1161930 CNV deletion 26073780
nsv466775 CNV loss 19166990
nsv470926 CNV loss 18288195
nsv516763 CNV gain+loss 19592680
nsv520736 CNV gain 19592680
nsv550147 CNV loss 21841781
nsv550148 CNV loss 21841781
nsv550162 CNV loss 21841781
nsv8611 CNV loss 18304495

Additional Variant Information for MIR4675 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4675
Leiden Open Variation Database (LOVD)
MIR4675

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4675 Gene

Disorders for MIR4675 Gene

Additional Disease Information for MIR4675

No disorders were found for MIR4675 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4675 Gene

Publications for MIR4675 Gene

  1. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. (PMID: 25017104) Kottyan LC … Rothenberg ME (Nature genetics 2014) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4675 Gene

Sources for MIR4675 Gene