microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4670 Gene

Subcategory (RNA class) for MIR4670 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4670 Gene

  • MicroRNA 4670 2 3 5
  • Hsa-Mir-4670 2 3
  • MIR4670 2 5
  • MIMAT0019750 50
  • MIMAT0019751 50
  • MI0017301 50

External Ids for MIR4670 Gene

Previous GeneCards Identifiers for MIR4670 Gene

  • GC09U901710
  • GC09M095291

Summaries for MIR4670 Gene

Entrez Gene Summary for MIR4670 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4670 Gene

MIR4670 (MicroRNA 4670) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4670 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4670 Gene

Genomics for MIR4670 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4670 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J092527 Enhancer 0.3 dbSUPER 600.7 -0.2 -248 1.6 HNF4A MIR4670 piR-55705-056 CENPP ASPN OMD ECM2
GH09J092523 Enhancer 0.7 ENCODE 0.7 +4.3 4342 0.8 IKZF1 JUND DPF2 HDAC1 SOX6 HMBOX1 CTBP1 HDAC2 GATAD2A ZSCAN29 OGN BICD2 MIR4670 ECM2 RF00017-7711 ASPN CENPP
GH09J092504 Enhancer 0.9 ENCODE dbSUPER 0.4 +21.3 21326 4.2 PRDM10 PRDM1 ZIC2 MNT CEBPB SP1 JUND BRCA1 NFE2 FOS CENPP ASPN RF00017-7711 MIR4670 ECM2
GH09J092501 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.3 +26.2 26186 1.1 CTCF ZNF316 MAFF SMC3 MAFK MAFG RAD21 RFX5 HOMEZ TFAP4 ECM2 RF00017-7711 ASPN MIR4670 CENPP
GH09J092513 Enhancer 0.5 Ensembl dbSUPER 0.4 +14.9 14858 0.4 POLR2A SMARCA4 MIR4670 RF00017-7711 ECM2 ASPN CENPP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4670 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4670 Gene

Genomic Locations for MIR4670 Gene
chr9:92,527,984-92,528,058
(GRCh38/hg38)
Size:
75 bases
Orientation:
Minus strand
chr9:95,290,266-95,290,340
(GRCh37/hg19)
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR4670 Gene

Genes around MIR4670 on UCSC Golden Path with GeneCards custom track
MIR4670 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4670 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4670 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4670 Gene

Proteins for MIR4670 Gene

Post-translational modifications for MIR4670 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4670 Gene

Domains & Families for MIR4670 Gene

Gene Families for MIR4670 Gene

HGNC:
genes like me logo Genes that share domains with MIR4670: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4670 Gene

Function for MIR4670 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4670 Gene

Localization for MIR4670 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4670 Gene

Pathways & Interactions for MIR4670 Gene

PathCards logo

SuperPathways for MIR4670 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4670 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4670 Gene

Drugs & Compounds for MIR4670 Gene

No Compound Related Data Available

Transcripts for MIR4670 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4670 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B566_9606 precursor_RNA 75 4

HGNC: 41862,

RefSeq: NR_039817,

Ensembl: ENST00000583240 (view in UCSC) ,

miRBase: MI0017301,

URS000015D252_9606 miRNA 22 3

RefSeq: NR_039817,

miRBase: MIMAT0019750,

ENA: FR772919.1:1..22:ncRNA,

URS00005CC60E_9606 miRNA 22 3

RefSeq: NR_039817,

miRBase: MIMAT0019751,

ENA: FR772918.1:1..22:ncRNA,

MIR4670 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4670 Gene

No ASD Table

Relevant External Links for MIR4670 Gene

GeneLoc Exon Structure for
MIR4670

No data available for mRNA/cDNA for MIR4670 Gene

Expression for MIR4670 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4670 Gene

Orthologs for MIR4670 Gene

Evolution for MIR4670 Gene

ENSEMBL:
Gene Tree for MIR4670 (if available)
TreeFam:
Gene Tree for MIR4670 (if available)

No data available for Orthologs for MIR4670 Gene

Paralogs for MIR4670 Gene

No data available for Paralogs for MIR4670 Gene

Variants for MIR4670 Gene

Additional dbSNP identifiers (rs#s) for MIR4670 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4670 Gene

Variant ID Type Subtype PubMed ID
esv3621081 CNV loss 21293372
esv3891693 CNV gain 25118596
nsv1047337 CNV loss 25217958

Additional Variant Information for MIR4670 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4670

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4670 Gene

Disorders for MIR4670 Gene

No disorders were found for MIR4670 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4670 Gene

Publications for MIR4670 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4670 Gene

Sources for MIR4670 Gene