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MIR4668 Gene(RNA Gene)

MicroRNA 4668

GCID:
GC09P111932
GIFtS:
14
Genes Participants
UDN Logo

Aliases for MIR4668 Gene

Subcategory (RNA class) for MIR4668 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4668 Gene

  • MicroRNA 4668 2 3 5
  • Hsa-Mir-4668 3
  • Mir-4668 3

External Ids for MIR4668 Gene

Previous GeneCards Identifiers for MIR4668 Gene

  • GC09U901716
  • GC09P114696

Summaries for MIR4668 Gene

Entrez Gene Summary for MIR4668 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4668 Gene

MIR4668 (MicroRNA 4668) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4668 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4668 Gene

Genomics for MIR4668 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR4668 Gene

Promoters and enhancers for MIR4668 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH09I111923 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.8 -4.7 -4658 7.1 PKNOX1 BMI1 BATF IRF4 ATF7 ETV6 BCLAF1 IKZF2 RUNX3 RXRA UGCG GNG10 MIR4668
GH09I111895 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 0.3 -31.8 -31751 10.5 HDGF PKNOX1 CLOCK SMAD1 ARNT ARID4B SIN3A DMAP1 YBX1 ZNF2 UGCG RNU6-1013P GNG10 ENSG00000224067 C9orf84 PTGR1 MIR4668
GH09I111937 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +6.2 6191 2.6 HDGF PKNOX1 SMAD1 RB1 BMI1 BATF IRF4 EGR1 ZNF143 ATF7 RNU6-710P RNU6-1013P GNG10 KIAA1958 C9orf84 PTBP3 SUSD1 DNAJC25 HSDL2 MIR4668
GH09I111957 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +28.1 28146 5.8 PKNOX1 CLOCK FOXA2 ARNT SIN3A FEZF1 ZNF213 FOS DEK REST RNU6-710P ENSG00000224067 C9orf84 RNU6-1013P GNG10 UGCG MIR4668
GH09I111914 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -16.0 -16048 3.9 HDGF FOXA2 SMAD1 NFIB BATF RAD21 RARA YY1 ATF7 IKZF2 RNU6-1013P GNG10 UGCG MIR4668
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4668 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4668 Gene

Genomic Locations for MIR4668 Gene
chr9:111,932,100-111,932,169
(GRCh38/hg38)
Size:
70 bases
Orientation:
Plus strand
chr9:114,694,380-114,694,449
(GRCh37/hg19)

Genomic View for MIR4668 Gene

Genes around MIR4668 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4668 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4668 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4668 Gene

Proteins for MIR4668 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4668 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4668 Gene

Domains & Families for MIR4668 Gene

Gene Families for MIR4668 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4668: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4668 Gene

Function for MIR4668 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for MIR4668 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4668 Gene

Localization for MIR4668 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4668 Gene

Pathways & Interactions for MIR4668 Gene

SuperPathways for MIR4668 Gene

PathCards logo More details on SuperPathways for MIR4668
No Data Available

Interacting Proteins for MIR4668 Gene

Gene Ontology (GO) - Biological Process for MIR4668 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4668 Gene

Drugs & Compounds for MIR4668 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4668 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4668 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4668 Gene

No ASD Table

Relevant External Links for MIR4668 Gene

GeneLoc Exon Structure for
MIR4668
ECgene alternative splicing isoforms for
MIR4668

Expression for MIR4668 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4668 Gene

mRNA expression in normal human tissues for MIR4668 Gene
mRNA expression by GTEx for MIR4668 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4668 Gene:

MIR4668
genes like me logo Genes that share expression patterns with MIR4668: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4668 Gene

Orthologs for MIR4668 Gene

Evolution for MIR4668 Gene

ENSEMBL:
Gene Tree for MIR4668 (if available)
TreeFam:
Gene Tree for MIR4668 (if available)

No data available for Orthologs for MIR4668 Gene

Paralogs for MIR4668 Gene

No data available for Paralogs for MIR4668 Gene

Variants for MIR4668 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for MIR4668 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000809131 -- 111,932,160(+) G/A/T non_coding_transcript_variant
rs1000863087 -- 111,932,571(+) A/C downstream_transcript_variant
rs1002437987 -- 111,932,669(+) T/G downstream_transcript_variant
rs1003488760 -- 111,930,809(+) A/T upstream_transcript_variant
rs1004436821 -- 111,932,431(+) G/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4668 Gene

Variant ID Type Subtype PubMed ID
nsv831690 CNV loss 17160897

Additional Variant Information for MIR4668 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4668

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4668 Gene

Disorders for MIR4668 Gene

Additional Disease Information for MIR4668

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4668 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4668 Gene

Publications for MIR4668 Gene

  1. Burkholderia pseudomallei survival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10. (PMID: 26151773) Li Q … Mao XH (Autophagy 2015) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  5. Ultraconserved element uc.372 drives hepatic lipid accumulation by suppressing miR-195/miR4668 maturation. (PMID: 29426937) Guo J … Li J (Nature communications 2018) 3

Products for MIR4668 Gene

Sources for MIR4668 Gene

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