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Aliases for MIR4657 Gene

Subcategory (RNA class) for MIR4657 Gene


Quality Score for this RNA gene is


Aliases for MIR4657 Gene

  • MicroRNA 4657 2 3 5
  • Hsa-Mir-4657 3
  • Mir-4657 3

External Ids for MIR4657 Gene

Previous GeneCards Identifiers for MIR4657 Gene

  • GC07U903199
  • GC07M044931
  • GC07M044932
  • GC07M044935
  • GC07M044881
  • GC07M044880

Summaries for MIR4657 Gene

Entrez Gene Summary for MIR4657 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4657 Gene

MIR4657 (MicroRNA 4657) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR4657 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR4657

Additional gene information for MIR4657 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR4657 Gene

Genomics for MIR4657 Gene

GeneHancer (GH) Regulatory Elements for MIR4657 Gene

Promoters and enhancers for MIR4657 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I044880 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.8 -3.3 -3295 9.8 HDGF PKNOX1 CLOCK SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ENSG00000272768 PURB PIR54023 H2AFV LINC01952 SNHG15 MYO1G ENSG00000228596 PPIA ZMIZ2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4657 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4657 Gene

Genomic Locations for MIR4657 Gene
53 bases
Minus strand

Genomic View for MIR4657 Gene

Genes around MIR4657 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4657 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4657 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4657 Gene

ORGUL Member Location for MIR4657 Gene

ORGUL Member Location for MIR4657 gene

Proteins for MIR4657 Gene

Post-translational modifications for MIR4657 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4657 Gene

Domains & Families for MIR4657 Gene

Gene Families for MIR4657 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4657: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4657 Gene

Function for MIR4657 Gene

Phenotypes From GWAS Catalog for MIR4657 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4657 Gene

Localization for MIR4657 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4657 Gene

Pathways & Interactions for MIR4657 Gene

SuperPathways for MIR4657 Gene

No Data Available

Interacting Proteins for MIR4657 Gene

Gene Ontology (GO) - Biological Process for MIR4657 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4657 Gene

Drugs & Compounds for MIR4657 Gene

No Compound Related Data Available

Transcripts for MIR4657 Gene

fRNAdb Secondary structures for MIR4657 Gene

  • hsa-miR-4657_MIMAT0019724_Homo_sapiens_miR-4657_mature

mRNA/cDNA for MIR4657 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4657 Gene

No ASD Table

Relevant External Links for MIR4657 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4657 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4657 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4657 Gene:

genes like me logo Genes that share expression patterns with MIR4657: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4657 Gene

Orthologs for MIR4657 Gene

Evolution for MIR4657 Gene

Gene Tree for MIR4657 (if available)
Gene Tree for MIR4657 (if available)

No data available for Orthologs for MIR4657 Gene

Paralogs for MIR4657 Gene

No data available for Paralogs for MIR4657 Gene

Variants for MIR4657 Gene

Sequence variations from dbSNP and Humsavar for MIR4657 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000302089 -- 44,882,993(-) G/A upstream_transcript_variant
rs1000485322 -- 44,882,714(-) A/T upstream_transcript_variant
rs1000615092 -- 44,881,412(-) TGGAGTG/TG downstream_transcript_variant
rs1000682069 -- 44,882,630(-) T/C upstream_transcript_variant
rs1000844159 -- 44,882,391(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4657 Gene

Variant ID Type Subtype PubMed ID
nsv830985 CNV loss 17160897

Additional Variant Information for MIR4657 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4657 Gene

Disorders for MIR4657 Gene

Additional Disease Information for MIR4657

No disorders were found for MIR4657 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4657 Gene

Publications for MIR4657 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  4. Identification and classification of conserved RNA secondary structures in the human genome. (PMID: 16628248) Pedersen JS … Haussler D (PLoS computational biology 2006) 1
  5. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang KC … Mattick JS (Nucleic acids research 2005) 1

Products for MIR4657 Gene

Sources for MIR4657 Gene

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