microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4655 Gene

Subcategory (RNA class) for MIR4655 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR4655 Gene

  • MicroRNA 4655 2 3 5
  • Hsa-Mir-4655 3
  • MIMAT0019722 53
  • MIMAT0019721 53
  • MI0017283 53
  • MIR4655 2

External Ids for MIR4655 Gene

Previous GeneCards Identifiers for MIR4655 Gene

  • GC07U903196
  • GC07M001886

Summaries for MIR4655 Gene

Entrez Gene Summary for MIR4655 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4655 Gene

MIR4655 (MicroRNA 4655) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4655 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4655 Gene

Genomics for MIR4655 Gene

GeneHancer (GH) Regulatory Elements for MIR4655 Gene

Promoters and enhancers for MIR4655 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4655 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4655 Gene

Genomic Locations for MIR4655 Gene
chr7:1,844,180-1,844,253
(GRCh38/hg38)
Size:
74 bases
Orientation:
Minus strand
chr7:1,883,816-1,883,889
(GRCh37/hg19)
Size:
74 bases
Orientation:
Minus strand

Genomic View for MIR4655 Gene

Genes around MIR4655 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4655 Gene

Proteins for MIR4655 Gene

Post-translational modifications for MIR4655 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4655 Gene

Domains & Families for MIR4655 Gene

Gene Families for MIR4655 Gene

HGNC:
genes like me logo Genes that share domains with MIR4655: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4655 Gene

Function for MIR4655 Gene

Phenotypes From GWAS Catalog for MIR4655 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4655 Gene

Localization for MIR4655 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4655 Gene

Pathways & Interactions for MIR4655 Gene

PathCards logo

SuperPathways for MIR4655 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4655 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4655 Gene

Drugs & Compounds for MIR4655 Gene

No Compound Related Data Available

Transcripts for MIR4655 Gene

mRNA/cDNA for MIR4655 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(2) ENA transcripts :
(3) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4655 Gene

No ASD Table

Relevant External Links for MIR4655 Gene

GeneLoc Exon Structure for
MIR4655
ECgene alternative splicing isoforms for
MIR4655

Expression for MIR4655 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4655 Gene:

MIR4655
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4655 Gene

Orthologs for MIR4655 Gene

Evolution for MIR4655 Gene

ENSEMBL:
Gene Tree for MIR4655 (if available)
TreeFam:
Gene Tree for MIR4655 (if available)

No data available for Orthologs for MIR4655 Gene

Paralogs for MIR4655 Gene

No data available for Paralogs for MIR4655 Gene

Variants for MIR4655 Gene

Sequence variations from dbSNP and Humsavar for MIR4655 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000200412 -- 1,844,012(-) G/T downstream_transcript_variant
rs1000230071 -- 1,844,936(-) G/C upstream_transcript_variant
rs1000567940 -- 1,844,667(-) G/C/T upstream_transcript_variant
rs1000634500 -- 1,843,791(-) G/A downstream_transcript_variant
rs1000708173 -- 1,845,076(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4655 Gene

Variant ID Type Subtype PubMed ID
nsv1017814 CNV gain 25217958
nsv1030397 CNV gain 25217958
nsv471193 CNV loss 18288195
nsv509186 CNV insertion 20534489
nsv5616 CNV deletion 18451855
nsv605833 CNV loss 21841781
nsv830883 CNV loss 17160897
nsv950788 CNV deletion 24416366

Additional Variant Information for MIR4655 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4655

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4655 Gene

Disorders for MIR4655 Gene

Additional Disease Information for MIR4655

No disorders were found for MIR4655 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4655 Gene

Publications for MIR4655 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR4655 Gene

Sources for MIR4655 Gene