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Aliases for MIR4650-1 Gene

Subcategory (RNA class) for MIR4650-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4650-1 Gene

  • MicroRNA 4650-1 2 3 5
  • Hsa-Mir-4650-1 3

External Ids for MIR4650-1 Gene

Previous GeneCards Identifiers for MIR4650-1 Gene

  • GC07U903189
  • GC07M066579

Summaries for MIR4650-1 Gene

Entrez Gene Summary for MIR4650-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4650-1 Gene

MIR4650-1 (MicroRNA 4650-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4650-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4650-1 Gene

Genomics for MIR4650-1 Gene

GeneHancer (GH) Regulatory Elements for MIR4650-1 Gene

Promoters and enhancers for MIR4650-1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I067114 Enhancer 0.8 Ensembl dbSUPER 550.8 -0.5 -504 0.2 SMARCE1 MEIS2 L3MBTL2 REST ELF1 E4F1 ATF2 ATF4 FOXK2 PHF20 MIR4650-1 RABGEF1 TYW1 GC07P067259
GH07I067127 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -15.0 -15036 3.3 HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF213 TYW1 RABGEF1 STAG3L4 LOC644794 MIR4650-1 GC07P067259
GH07I067102 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 +9.7 9682 3.5 HDAC1 MEIS2 PKNOX1 ARNT ETV1 TAL1 NCOR1 CBFA2T2 NFE2 SMARCE1 TYW1 STAG3L4 RABGEF1 MIR4650-1 ENSG00000233383
GH07I067099 Enhancer 1 ENCODE dbSUPER 0.4 +13.5 13521 1.9 HDAC1 ARNT FEZF1 TCF12 EGR1 ZSCAN5C PHF21A ZBTB2 ZEB2 ZNF843 TYW1 ENSG00000233383 MIR4650-1
GH07I067192 Enhancer 0.7 Ensembl ENCODE 0.2 -78.5 -78466 2.1 ZNF316 FOXA2 NRF1 HNF4A EMSY TYW1 GC07P067259 MIR4650-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4650-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4650-1 Gene

Genomic Locations for MIR4650-1 Gene
76 bases
Minus strand

Genomic View for MIR4650-1 Gene

Genes around MIR4650-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4650-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4650-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4650-1 Gene

ORGUL Member Location for MIR4650-1 Gene

ORGUL Member Location for MIR4650-1 gene

Proteins for MIR4650-1 Gene

Post-translational modifications for MIR4650-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4650-1 Gene

Domains & Families for MIR4650-1 Gene

Gene Families for MIR4650-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4650-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4650-1 Gene

Function for MIR4650-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4650-1 Gene

Localization for MIR4650-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4650-1 Gene

Pathways & Interactions for MIR4650-1 Gene

SuperPathways for MIR4650-1 Gene

No Data Available

Interacting Proteins for MIR4650-1 Gene

Gene Ontology (GO) - Biological Process for MIR4650-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4650-1 Gene

Drugs & Compounds for MIR4650-1 Gene

No Compound Related Data Available

Transcripts for MIR4650-1 Gene

mRNA/cDNA for MIR4650-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4650-1 Gene

No ASD Table

Relevant External Links for MIR4650-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4650-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4650-1 Gene

Orthologs for MIR4650-1 Gene

Evolution for MIR4650-1 Gene

Gene Tree for MIR4650-1 (if available)
Gene Tree for MIR4650-1 (if available)

No data available for Orthologs for MIR4650-1 Gene

Paralogs for MIR4650-1 Gene

No data available for Paralogs for MIR4650-1 Gene

Variants for MIR4650-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4650-1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1005782320 -- 67,115,579(-) A/G upstream_transcript_variant
rs1005813100 -- 67,114,175(-) C/A downstream_transcript_variant
rs1006116037 -- 67,113,831(-) G/T downstream_transcript_variant
rs1007404223 -- 67,115,039(-) AG/ upstream_transcript_variant
rs1011987679 -- 67,114,124(-) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4650-1 Gene

Variant ID Type Subtype PubMed ID
nsv970525 CNV duplication 23825009
nsv966838 CNV duplication 23825009
nsv831019 CNV loss 17160897
nsv5774 CNV insertion 18451855
nsv520573 CNV gain+loss 19592680
nsv470310 CNV gain 18288195
nsv469716 CNV gain 16826518
nsv442053 CNV gain 18776908
nsv436901 CNV insertion 17901297
nsv1161562 CNV duplication 26073780
nsv1146102 OTHER inversion 26484159
nsv1020209 CNV gain 25217958
nsv1019945 CNV gain+loss 25217958
esv3891144 CNV gain 25118596
esv3891138 CNV gain 25118596
esv3891136 CNV gain 25118596
esv3613668 CNV gain 21293372
esv3613667 CNV loss 21293372
esv34349 CNV gain 17911159
esv33871 CNV loss 17666407
esv2761093 CNV loss 21179565
esv2759537 CNV gain+loss 17122850
esv2759535 CNV gain 17122850
dgv821n27 CNV gain 19166990
dgv6463n100 CNV gain 25217958
dgv6462n100 CNV gain 25217958
dgv6461n100 CNV gain 25217958
dgv6460n100 CNV gain 25217958
dgv6459n100 CNV loss 25217958
dgv62n64 CNV gain 17921354
dgv231e55 CNV gain 17911159
dgv1923e212 CNV gain 25503493
dgv1299e214 CNV gain 21293372
dgv11443n54 CNV gain 21841781
dgv11442n54 CNV gain 21841781
dgv1116n67 CNV gain 20364138

Additional Variant Information for MIR4650-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4650-1 Gene

Disorders for MIR4650-1 Gene

Additional Disease Information for MIR4650-1

No disorders were found for MIR4650-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4650-1 Gene

Publications for MIR4650-1 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4650-1 Gene

Sources for MIR4650-1 Gene

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