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Aliases for MIR4639 Gene

Subcategory (RNA class) for MIR4639 Gene


Quality Score for this RNA gene is


Aliases for MIR4639 Gene

  • MicroRNA 4639 2 3 5
  • Hsa-Mir-4639 3

External Ids for MIR4639 Gene

Previous GeneCards Identifiers for MIR4639 Gene

  • GC06U902227

Summaries for MIR4639 Gene

Entrez Gene Summary for MIR4639 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4639 Gene

MIR4639 (MicroRNA 4639) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4639 include Tooth Agenesis.

Additional gene information for MIR4639 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4639 Gene

Genomics for MIR4639 Gene

GeneHancer (GH) Regulatory Elements for MIR4639 Gene

Promoters and enhancers for MIR4639 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I016128 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.4 -11.2 -11187 4 MLX FEZF1 DMAP1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC ZFP41 MYLIP RNU6-1114P MIR4639
GH06I016136 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.8 -4.6 -4627 1.8 ZNF146 TEAD4 INSM2 FEZF1 FOSL1 ZNF366 POLR2A ADNP NFATC1 VEZF1 MIR4639 MYLIP
GH06I016144 Enhancer 0.8 dbSUPER 0.8 +3.8 3779 2.5 INSM2 MZF1 FEZF1 ZNF2 ZNF335 ZNF121 GLIS2 ZNF213 ZNF391 ZNF362 GC06M016150 MIR4639 MYLIP
GH06I016135 Enhancer 0.7 Ensembl dbSUPER 0.4 -6.2 -6246 0.6 HDGF POLR2A HMBOX1 NFE2 ZNF600 SUPT5H MIR4639 MYLIP
GH06I016133 Enhancer 0.6 Ensembl dbSUPER 0.4 -8.5 -8455 0.2 OSR2 PKNOX1 REST RNU6-1114P MYLIP MIR4639
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4639 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4639 Gene

Genomic Locations for MIR4639 Gene
69 bases
Plus strand

Genomic View for MIR4639 Gene

Genes around MIR4639 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4639 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4639 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4639 Gene

Proteins for MIR4639 Gene

Post-translational modifications for MIR4639 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4639 Gene

Domains & Families for MIR4639 Gene

Gene Families for MIR4639 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4639: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4639 Gene

Function for MIR4639 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4639 Gene

Localization for MIR4639 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4639 Gene

Pathways & Interactions for MIR4639 Gene

SuperPathways for MIR4639 Gene

No Data Available

Interacting Proteins for MIR4639 Gene

Gene Ontology (GO) - Biological Process for MIR4639 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4639 Gene

Drugs & Compounds for MIR4639 Gene

No Compound Related Data Available

Transcripts for MIR4639 Gene

mRNA/cDNA for MIR4639 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4639 Gene

No ASD Table

Relevant External Links for MIR4639 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4639 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4639 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4639 Gene:

genes like me logo Genes that share expression patterns with MIR4639: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4639 Gene

Orthologs for MIR4639 Gene

Evolution for MIR4639 Gene

Gene Tree for MIR4639 (if available)
Gene Tree for MIR4639 (if available)

No data available for Orthologs for MIR4639 Gene

Paralogs for MIR4639 Gene

No data available for Paralogs for MIR4639 Gene

Variants for MIR4639 Gene

Sequence variations from dbSNP and Humsavar for MIR4639 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000773486 -- 16,139,998(+) C/G upstream_transcript_variant
rs1001122504 -- 16,139,604(+) C/T upstream_transcript_variant
rs1003625312 -- 16,141,652(+) G/A downstream_transcript_variant
rs1003681492 -- 16,142,075(+) G/T downstream_transcript_variant
rs1004035555 -- 16,141,758(+) T/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4639 Gene

Variant ID Type Subtype PubMed ID
nsv5209 CNV insertion 18451855
nsv950132 CNV duplication 24416366

Additional Variant Information for MIR4639 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4639 Gene

Disorders for MIR4639 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR4639 Gene - From: GeneCards

Disorder Aliases PubMed IDs
tooth agenesis
  • familial tooth agenesis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR4639

genes like me logo Genes that share disorders with MIR4639: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4639 Gene

Publications for MIR4639 Gene

  1. Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis. (PMID: 27362534) Lu Y … Wang L (PloS one 2016) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4639 Gene

Sources for MIR4639 Gene

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