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Aliases for MIR4637 Gene

Subcategory (RNA class) for MIR4637 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4637 Gene

  • MicroRNA 4637 2 3 5
  • Hsa-Mir-4637 3

External Ids for MIR4637 Gene

Previous GeneCards Identifiers for MIR4637 Gene

  • GC05U901566

Summaries for MIR4637 Gene

Entrez Gene Summary for MIR4637 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4637 Gene

MIR4637 (MicroRNA 4637) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4637 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4637 Gene

Genomics for MIR4637 Gene

GeneHancer (GH) Regulatory Elements for MIR4637 Gene

Promoters and enhancers for MIR4637 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I014809 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +15.6 15605 2.3 PKNOX1 ATF1 IRF4 ZNF143 FOS ATF7 RUNX3 RXRA JUNB NFIL3 ANKH OTULIN FAM105A RBBP4P1 MIR4637
GH05I014868 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 0.3 -44.8 -44772 5.5 PKNOX1 SIN3A ZNF2 YY1 GLIS2 ZNF143 DEK REST SMARCB1 NFIL3 ANKH ENSG00000272057 MIR4637
GH05I014829 Enhancer 0.6 dbSUPER 0.8 -4.6 -4643 3.2 FOXA2 RXRA ZSCAN4 MAX REST RAD21 FOXA1 YY1 ZFHX2 JUND ANKH MIR4637
GH05I014816 Enhancer 0.8 ENCODE dbSUPER 0.4 +9.0 9011 1.7 MAX CEBPB EBF1 REST CEBPG RAD21 YY1 JUND ATF3 HNF4A MIR4637 RBBP4P1 ANKH
GH05I014805 Enhancer 0.7 ENCODE dbSUPER 0.4 +19.3 19280 2.2 RXRA GLIS1 ZBTB40 NR2F2 NR2C2 RBBP4P1 MIR4637 ANKH
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4637 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4637 Gene

Genomic Locations for MIR4637 Gene
chr5:14,825,929-14,826,012
(GRCh38/hg38)
Size:
84 bases
Orientation:
Minus strand
chr5:14,826,038-14,826,121
(GRCh37/hg19)

Genomic View for MIR4637 Gene

Genes around MIR4637 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4637 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4637 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4637 Gene

ORGUL Member Location for MIR4637 Gene

ORGUL Member Location for MIR4637 gene

Proteins for MIR4637 Gene

Post-translational modifications for MIR4637 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4637 Gene

Domains & Families for MIR4637 Gene

Gene Families for MIR4637 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4637: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4637 Gene

Function for MIR4637 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4637 Gene

Localization for MIR4637 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4637 Gene

Pathways & Interactions for MIR4637 Gene

SuperPathways for MIR4637 Gene

No Data Available

Interacting Proteins for MIR4637 Gene

Gene Ontology (GO) - Biological Process for MIR4637 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4637 Gene

Drugs & Compounds for MIR4637 Gene

No Compound Related Data Available

Transcripts for MIR4637 Gene

mRNA/cDNA for MIR4637 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4637 Gene

No ASD Table

Relevant External Links for MIR4637 Gene

GeneLoc Exon Structure for
MIR4637
ECgene alternative splicing isoforms for
MIR4637

Expression for MIR4637 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4637 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4637 Gene:

MIR4637
genes like me logo Genes that share expression patterns with MIR4637: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4637 Gene

Orthologs for MIR4637 Gene

Evolution for MIR4637 Gene

ENSEMBL:
Gene Tree for MIR4637 (if available)
TreeFam:
Gene Tree for MIR4637 (if available)

No data available for Orthologs for MIR4637 Gene

Paralogs for MIR4637 Gene

No data available for Paralogs for MIR4637 Gene

Variants for MIR4637 Gene

Sequence variations from dbSNP and Humsavar for MIR4637 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000001167 -- 14,827,426(-) G/A upstream_transcript_variant
rs1001631839 -- 14,826,506(-) G/T upstream_transcript_variant
rs1003519747 -- 14,827,844(-) T/C upstream_transcript_variant
rs1004063503 -- 14,827,500(-) C/T upstream_transcript_variant
rs10043575 -- 14,826,577(-) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4637 Gene

Variant ID Type Subtype PubMed ID
nsv830212 CNV loss 17160897
nsv1148187 OTHER inversion 26484159
nsv1018187 CNV gain 25217958

Additional Variant Information for MIR4637 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4637

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4637 Gene

Disorders for MIR4637 Gene

Additional Disease Information for MIR4637

No disorders were found for MIR4637 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4637 Gene

Publications for MIR4637 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4637 Gene

Sources for MIR4637 Gene

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