microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4636 Gene

Subcategory (RNA class) for MIR4636 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR4636 Gene

  • MicroRNA 4636 2 3 5
  • Hsa-Mir-4636 3
  • MIMAT0019693 51
  • MI0017263 51
  • Mir-4636 3
  • MIR4636 2

External Ids for MIR4636 Gene

Previous GeneCards Identifiers for MIR4636 Gene

  • GC05U901564

Summaries for MIR4636 Gene

Entrez Gene Summary for MIR4636 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4636 Gene

MIR4636 (MicroRNA 4636) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4636 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4636 Gene

Genomics for MIR4636 Gene

GeneHancer (GH) Regulatory Elements for MIR4636 Gene

Promoters and enhancers for MIR4636 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J009054 Enhancer 0.4 Ensembl 500.7 -1.3 -1306 0.8 MAFF MAFK CEBPB MIR4636 lnc-CCT5-31 SEMA5A
GH05J009057 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -5.8 -5834 4.7 JUND FOS REST NR2F2 POLR2A GABPA MAFK IKZF1 CTCF SMARCA4 SEMA5A MIR4636 lnc-CCT5-31
GH05J009045 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.4 +6.6 6613 3 FOS JUND GATA2 RAD21 BHLHE40 MAZ CHD1 CEBPB STAT3 SEMA5A MIR4636 lnc-TAS2R1-24 ENSG00000250619
GH05J009056 Enhancer 0.3 Ensembl 0.7 -2.2 -2206 0.2 TBX21 FOS MIR4636 lnc-CCT5-31 SEMA5A
GH05J009068 Enhancer 0.4 Ensembl ENCODE 0.4 -15.9 -15929 1.8 USF2 lnc-CCT5-31 MIR4636 SEMA5A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4636 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4636 Gene

Genomic Locations for MIR4636 Gene
chr5:9,053,816-9,053,895
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand
chr5:9,053,928-9,054,007
(GRCh37/hg19)
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4636 Gene

Genes around MIR4636 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4636 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4636 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4636 Gene

Proteins for MIR4636 Gene

Post-translational modifications for MIR4636 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4636 Gene

Domains & Families for MIR4636 Gene

Gene Families for MIR4636 Gene

HGNC:
genes like me logo Genes that share domains with MIR4636: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4636 Gene

Function for MIR4636 Gene

Phenotypes From GWAS Catalog for MIR4636 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4636 Gene

Localization for MIR4636 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4636 Gene

Pathways & Interactions for MIR4636 Gene

PathCards logo

SuperPathways for MIR4636 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4636 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4636 Gene

Drugs & Compounds for MIR4636 Gene

No Compound Related Data Available

Transcripts for MIR4636 Gene

mRNA/cDNA for MIR4636 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
4 ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4636 Gene

No ASD Table

Relevant External Links for MIR4636 Gene

GeneLoc Exon Structure for
MIR4636

Expression for MIR4636 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4636 Gene

genes like me logo Genes that share expression patterns with MIR4636: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4636 Gene

Orthologs for MIR4636 Gene

Evolution for MIR4636 Gene

ENSEMBL:
Gene Tree for MIR4636 (if available)
TreeFam:
Gene Tree for MIR4636 (if available)

No data available for Orthologs for MIR4636 Gene

Paralogs for MIR4636 Gene

No data available for Paralogs for MIR4636 Gene

Variants for MIR4636 Gene

Additional dbSNP identifiers (rs#s) for MIR4636 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4636 Gene

Variant ID Type Subtype PubMed ID
nsv597069 CNV gain 21841781

Additional Variant Information for MIR4636 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4636

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4636 Gene

Disorders for MIR4636 Gene

Additional Disease Information for MIR4636

No disorders were found for MIR4636 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4636 Gene

Publications for MIR4636 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4636 Gene

Sources for MIR4636 Gene