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Aliases for MIR4538 Gene

Subcategory (RNA class) for MIR4538 Gene


Quality Score for this RNA gene is


Aliases for MIR4538 Gene

  • MicroRNA 4538 2 3 5
  • Hsa-Mir-4538 3

External Ids for MIR4538 Gene

Previous GeneCards Identifiers for MIR4538 Gene

  • GC14U901287
  • GC14M107727
  • GC14M105927
  • GC14M105989
  • GC14M106000
  • GC14M106013
  • GC14M106157
  • GC14M106195
  • GC14M106313

Summaries for MIR4538 Gene

Entrez Gene Summary for MIR4538 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4538 Gene

MIR4538 (MicroRNA 4538) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4538 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4538 Gene

Genomics for MIR4538 Gene

GeneHancer (GH) Regulatory Elements for MIR4538 Gene

Promoters and enhancers for MIR4538 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I105858 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.8 -2.2 -2212 8.6 PKNOX1 SMAD1 NFIB BMI1 BATF KLF5 IRF4 ATF7 ETV6 BCLAF1 MIR4537 ENSG00000225200 ENSG00000257270 CDCA4 MTA1 TEX22 IGHJ3 IGHJ3P IGHJ4 IGHJ5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4538 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4538 Gene

Genomic Locations for MIR4538 Gene
78 bases
Minus strand

Genomic View for MIR4538 Gene

Genes around MIR4538 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4538 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4538 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4538 Gene

Proteins for MIR4538 Gene

Post-translational modifications for MIR4538 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4538 Gene

Domains & Families for MIR4538 Gene

Gene Families for MIR4538 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4538: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4538 Gene

Function for MIR4538 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4538 Gene

Localization for MIR4538 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4538 Gene

Pathways & Interactions for MIR4538 Gene

SuperPathways for MIR4538 Gene

No Data Available

Interacting Proteins for MIR4538 Gene

Gene Ontology (GO) - Biological Process for MIR4538 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4538 Gene

Drugs & Compounds for MIR4538 Gene

No Compound Related Data Available

Transcripts for MIR4538 Gene

mRNA/cDNA for MIR4538 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4538 Gene

No ASD Table

Relevant External Links for MIR4538 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4538 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4538 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4538 Gene

This gene is overexpressed in Spleen (x15.5) and Small Intestine - Terminal Ileum (x10.9).

NURSA nuclear receptor signaling pathways regulating expression of MIR4538 Gene:

genes like me logo Genes that share expression patterns with MIR4538: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4538 Gene

Orthologs for MIR4538 Gene

Evolution for MIR4538 Gene

Gene Tree for MIR4538 (if available)
Gene Tree for MIR4538 (if available)

No data available for Orthologs for MIR4538 Gene

Paralogs for MIR4538 Gene

No data available for Paralogs for MIR4538 Gene

Variants for MIR4538 Gene

Sequence variations from dbSNP and Humsavar for MIR4538 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs111174256 -- 105,858,270(-) C/A upstream_transcript_variant
rs111207013 -- 105,857,847(-) G/A downstream_transcript_variant
rs111207015 -- 105,858,237(-) A/C non_coding_transcript_variant
rs111207016 -- 105,858,667(-) T/C upstream_transcript_variant
rs111480641 -- 105,859,719(-) G/A upstream_transcript_variant

Additional Variant Information for MIR4538 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4538 Gene

Disorders for MIR4538 Gene

Additional Disease Information for MIR4538

No disorders were found for MIR4538 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4538 Gene

Publications for MIR4538 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4538 Gene

Sources for MIR4538 Gene

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