microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4529 Gene

Data sources for MIR4529 Gene:

Subcategory (RNA class) for MIR4529 Gene

miRNA

Aliases for MIR4529 Gene

External Ids for MIR4529 Gene

Previous GeneCards Identifiers for MIR4529 Gene

  • GC18U900671
  • GC18P053150

Summaries for MIR4529 Gene

Entrez Gene Summary for MIR4529 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4529 Gene

MIR4529 (MicroRNA 4529) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4529 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4529 Gene

Genomics for MIR4529 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4529 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J055476 Promoter/Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 250.7 -1.4 -1417 2 IKZF1 IRF2 CTCF TAL1 EBF1 ADNP HNF4A JUND RAD21 TEAD4 MIR4529 TCF4-AS1 lnc-CCDC68-5 lnc-CCDC68-2 TCF4 CCDC68
GH18J055488 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +8.3 8280 5.4 BCL11A FEZF1 IRF4 YY1 BHLHE40 BATF ATF2 JUNB RCOR1 SP1 TCF4-AS2 MIR4529 lnc-CCDC68-5 lnc-CCDC68-2 TCF4 CCDC68
GH18J055473 Enhancer 0.8 UCNEbase Ensembl 0.4 -5.6 -5620 0.8 JUND RCOR1 GATA2 POLR2A CHD2 EP300 PRDM1 MIR4529 TCF4-AS1 lnc-CCDC68-5 lnc-CCDC68-2 TCF4 CCDC68
GH18J055465 Enhancer 0.6 Ensembl ENCODE 0.4 -12.7 -12720 3.8 SPI1 NANOG CHD2 MIR4529 TCF4-AS1 lnc-CCDC68-5 lnc-CCDC68-2 TCF4 CCDC68
GH18J055457 Enhancer 0.7 Ensembl dbSUPER 0.3 -20.2 -20220 1.6 MEIS2 SOX6 IKZF1 FOXK2 MNT NR2F2 NR2F1 TCF4 TCF4-AS1 MIR4529 lnc-CCDC68-5 lnc-CCDC68-2 CCDC68
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4529 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4529 Gene

Latest Assembly
chr18:55,479,221-55,479,298
(GRCh38/hg38)
Size:
78 bases
Orientation:
Plus strand

Previous Assembly
chr18:53,146,452-53,146,529
(GRCh37/hg19 by Entrez Gene)
Size:
78 bases
Orientation:
Plus strand

chr18:53,146,452-53,146,529
(GRCh37/hg19 by Ensembl)
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR4529 Gene

Genes around MIR4529 on UCSC Golden Path with GeneCards custom track
MIR4529 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4529 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4529 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4529 Gene

Proteins for MIR4529 Gene

Post-translational modifications for MIR4529 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4529 Gene

Domains & Families for MIR4529 Gene

Gene Families for MIR4529 Gene

HGNC:
genes like me logo Genes that share domains with MIR4529: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4529 Gene

Function for MIR4529 Gene

Phenotypes From GWAS Catalog for MIR4529 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4529 Gene

Localization for MIR4529 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4529 Gene

Pathways & Interactions for MIR4529 Gene

PathCards logo

SuperPathways for MIR4529 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4529 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4529 Gene

Drugs & Compounds for MIR4529 Gene

No Compound Related Data Available

Transcripts for MIR4529 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4529 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CE31_9606 pre_miRNA 78 3

RefSeq: NR_039754,

Ensembl: ENST00000578110 (view in UCSC) ,

miRBase: MI0016896,

URS00005D0CA3_9606 miRNA 22 3

RefSeq: NR_039754,

miRBase: MIMAT0019236,

ENA: FR772853.1:1..22:ncRNA,

URS000075E7E0_9606 miRNA 21 2

RefSeq: NR_039754,

miRBase: MIMAT0019068,

URS000044E8CE_9606 miRNA 22 1

ENA: FR772852.1:1..22:ncRNA,

MIR4529 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4529 Gene

No ASD Table

Relevant External Links for MIR4529 Gene

GeneLoc Exon Structure for
MIR4529

No data available for mRNA/cDNA for MIR4529 Gene

Expression for MIR4529 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4529

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4529 Gene

Orthologs for MIR4529 Gene

Evolution for MIR4529 Gene

ENSEMBL:
Gene Tree for MIR4529 (if available)
TreeFam:
Gene Tree for MIR4529 (if available)

No data available for Orthologs for MIR4529 Gene

Paralogs for MIR4529 Gene

No data available for Paralogs for MIR4529 Gene

Variants for MIR4529 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4529 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4529 Gene

Variant ID Type Subtype PubMed ID
nsv1120116 OTHER inversion 24896259

Additional Variant Information for MIR4529 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4529

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4529 Gene

Disorders for MIR4529 Gene

Additional Disease Information for MIR4529

No disorders were found for MIR4529 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4529 Gene

Publications for MIR4529 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4529 Gene

Sources for MIR4529 Gene