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Aliases for MIR4524A Gene

Subcategory (RNA class) for MIR4524A Gene


Quality Score for this RNA gene is


Aliases for MIR4524A Gene

  • MicroRNA 4524a 2 3 5
  • MicroRNA 4524 2 3
  • Hsa-Mir-4524a 3
  • Hsa-Mir-4524 3
  • Mir-4524a 3
  • MIR4524 3

External Ids for MIR4524A Gene

Previous HGNC Symbols for MIR4524A Gene

  • MIR4524

Previous GeneCards Identifiers for MIR4524A Gene

  • GC17U901689
  • GC17P067099
  • GC17M067098

Summaries for MIR4524A Gene

Entrez Gene Summary for MIR4524A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4524A Gene

MIR4524A (MicroRNA 4524a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4524A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4524A Gene

Genomics for MIR4524A Gene

GeneHancer (GH) Regulatory Elements for MIR4524A Gene

Promoters and enhancers for MIR4524A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I069099 Enhancer 0.4 FANTOM5 550.8 -0.1 -69 0.1 CREB1 MIR4524A MIR4524B ABCA6 ABCA9 ABCA10 GC17M069120
GH17I069103 Enhancer 0.9 ENCODE 0.8 -4.1 -4103 0.2 PKNOX1 SMAD1 ATF1 FOXA2 TCF12 GATA2 ATF7 NCOA1 ZNF592 MBD2 ABCA6 ABCA9 ABCA10 MIR4524A GC17M069120
GH17I069115 Enhancer 0.8 ENCODE 0.4 -16.4 -16388 1.4 HDGF SMAD1 IRF4 RAD21 YY1 ZNF143 ATF7 ETV6 BCLAF1 IKZF2 ABCA10 ABCA6 ABCA9 ABCA5 GC17M069120 MIR4524A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4524A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4524A Gene

Genomic Locations for MIR4524A Gene
69 bases
Minus strand

Genomic View for MIR4524A Gene

Genes around MIR4524A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4524A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4524A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4524A Gene

ORGUL Member Location for MIR4524A Gene

ORGUL Member Location for MIR4524A gene

Proteins for MIR4524A Gene

Post-translational modifications for MIR4524A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4524A Gene

Domains & Families for MIR4524A Gene

Gene Families for MIR4524A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4524A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4524A Gene

Function for MIR4524A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4524A Gene

Localization for MIR4524A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4524A Gene

Pathways & Interactions for MIR4524A Gene

SuperPathways for MIR4524A Gene

No Data Available

Interacting Proteins for MIR4524A Gene

Gene Ontology (GO) - Biological Process for MIR4524A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4524A Gene

Drugs & Compounds for MIR4524A Gene

No Compound Related Data Available

Transcripts for MIR4524A Gene

mRNA/cDNA for MIR4524A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4524A Gene

No ASD Table

Relevant External Links for MIR4524A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4524A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4524A Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4524A Gene

Orthologs for MIR4524A Gene

Evolution for MIR4524A Gene

Gene Tree for MIR4524A (if available)
Gene Tree for MIR4524A (if available)

No data available for Orthologs for MIR4524A Gene

Paralogs for MIR4524A Gene

No data available for Paralogs for MIR4524A Gene

Variants for MIR4524A Gene

Sequence variations from dbSNP and Humsavar for MIR4524A Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000494590 -- 69,100,273(-) C/T upstream_transcript_variant
rs1002304335 -- 69,101,324(-) G/C upstream_transcript_variant
rs1004460738 -- 69,100,818(-) A/T upstream_transcript_variant
rs1005015253 -- 69,099,886(-) G/A upstream_transcript_variant
rs1005567259 -- 69,099,258(-) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4524A Gene

Variant ID Type Subtype PubMed ID
nsv833526 CNV gain 17160897
nsv470598 CNV loss 18288195

Additional Variant Information for MIR4524A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4524A Gene

Disorders for MIR4524A Gene

Additional Disease Information for MIR4524A

No disorders were found for MIR4524A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4524A Gene

Publications for MIR4524A Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 58
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  5. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58

Products for MIR4524A Gene

Sources for MIR4524A Gene

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