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Aliases for MIR4517 Gene

Subcategory (RNA class) for MIR4517 Gene


Quality Score for this RNA gene is


Aliases for MIR4517 Gene

  • MicroRNA 4517 2 3 5
  • Hsa-Mir-4517 3
  • Mir-4517 3

External Ids for MIR4517 Gene

Previous GeneCards Identifiers for MIR4517 Gene

  • GC16U901341
  • GC16P028971

Summaries for MIR4517 Gene

Entrez Gene Summary for MIR4517 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4517 Gene

MIR4517 (MicroRNA 4517) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4517 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4517 Gene

Genomics for MIR4517 Gene

GeneHancer (GH) Regulatory Elements for MIR4517 Gene

Promoters and enhancers for MIR4517 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I028950 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.4 -7.3 -7263 2.4 HDGF PKNOX1 ARID4B SIN3A ZNF2 ZBTB7B YY1 POLR2B E2F8 ZNF143 NFATC2IP SGF29 ATXN2L ENSG00000260853 SMG1P2 SPNS1 ENSG00000260367 EIF3C SULT1A2 NPIPB8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4517 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4517 Gene

Genomic Locations for MIR4517 Gene
79 bases
Plus strand

Genomic View for MIR4517 Gene

Genes around MIR4517 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4517 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4517 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4517 Gene

Proteins for MIR4517 Gene

Post-translational modifications for MIR4517 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4517 Gene

Domains & Families for MIR4517 Gene

Gene Families for MIR4517 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4517: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4517 Gene

Function for MIR4517 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4517 Gene

Localization for MIR4517 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4517 Gene

Pathways & Interactions for MIR4517 Gene

SuperPathways for MIR4517 Gene

No Data Available

Interacting Proteins for MIR4517 Gene

Gene Ontology (GO) - Biological Process for MIR4517 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4517 Gene

Drugs & Compounds for MIR4517 Gene

No Compound Related Data Available

Transcripts for MIR4517 Gene

mRNA/cDNA for MIR4517 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4517 Gene

No ASD Table

Relevant External Links for MIR4517 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4517 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4517 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4517 Gene:

genes like me logo Genes that share expression patterns with MIR4517: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4517 Gene

Orthologs for MIR4517 Gene

Evolution for MIR4517 Gene

Gene Tree for MIR4517 (if available)
Gene Tree for MIR4517 (if available)

No data available for Orthologs for MIR4517 Gene

Paralogs for MIR4517 Gene

No data available for Paralogs for MIR4517 Gene

Variants for MIR4517 Gene

Sequence variations from dbSNP and Humsavar for MIR4517 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1002720338 -- 28,958,031(+) G/A upstream_transcript_variant
rs1004513132 -- 28,957,261(+) T/C upstream_transcript_variant
rs1004968909 -- 28,956,981(+) C/T upstream_transcript_variant
rs1006191179 -- 28,958,316(+) A/G upstream_transcript_variant
rs1007852188 -- 28,959,057(+) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4517 Gene

Variant ID Type Subtype PubMed ID
nsv571808 CNV gain 21841781
nsv571805 CNV loss 21841781
nsv519100 CNV gain 19592680
nsv518648 CNV loss 19592680
nsv457480 CNV gain 19166990
nsv1059555 CNV gain 25217958
esv3892826 CNV gain+loss 25118596
esv3570454 CNV gain 25503493
esv2758640 CNV gain+loss 17122850
dgv4987n54 CNV gain 21841781
dgv2831n100 CNV gain 25217958
dgv2830n100 CNV gain 25217958

Additional Variant Information for MIR4517 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4517 Gene

Disorders for MIR4517 Gene

Additional Disease Information for MIR4517

No disorders were found for MIR4517 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4517 Gene

Publications for MIR4517 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4517 Gene

Sources for MIR4517 Gene

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