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Aliases for MIR4499 Gene

Subcategory (RNA class) for MIR4499 Gene


Quality Score for this RNA gene is


Aliases for MIR4499 Gene

  • MicroRNA 4499 2 3 5
  • Hsa-Mir-4499 3

External Ids for MIR4499 Gene

Previous GeneCards Identifiers for MIR4499 Gene

  • GC13U900858
  • GC13M021008

Summaries for MIR4499 Gene

Entrez Gene Summary for MIR4499 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4499 Gene

MIR4499 (MicroRNA 4499) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4499 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4499 Gene

Genomics for MIR4499 Gene

GeneHancer (GH) Regulatory Elements for MIR4499 Gene

Promoters and enhancers for MIR4499 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I020435 Enhancer 0.4 ENCODE 550.8 -2.0 -1951 0.2 USF1 EZH2 MIR4499 GJB6 CRYL1
GH13I020418 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 +14.0 13991 1.9 SMAD1 SIN3A BMI1 BATF KLF5 IRF4 BRCA1 RFX5 ZNF366 SCRT2 CRYL1 MIR4499 LOC105370102
GH13I020428 Enhancer 0.6 dbSUPER 0.8 +3.5 3507 3.7 MEIS2 PKNOX1 RXRA MAX MAFG RAD21 GABPA ZNF316 NFE2 HNF4A CRYL1 MIR4499 LOC105370102
GH13I020517 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.2 -88.8 -88795 9.4 FOXA2 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS SP3 NFYC ZHX2 CRYL1 MIR4499
GH13I020474 Enhancer 1.3 FANTOM5 Ensembl ENCODE 0.3 -42.2 -42161 3.2 INSM2 FEZF1 ZNF2 IRF4 SCRT2 ETV6 BCLAF1 IKZF2 RUNX3 EGR2 CRYL1 IFT88 MIR4499
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4499 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4499 Gene

Genomic Locations for MIR4499 Gene
69 bases
Minus strand

Genomic View for MIR4499 Gene

Genes around MIR4499 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4499 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4499 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4499 Gene

Proteins for MIR4499 Gene

Post-translational modifications for MIR4499 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4499 Gene

Domains & Families for MIR4499 Gene

Gene Families for MIR4499 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4499: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4499 Gene

Function for MIR4499 Gene

Phenotypes From GWAS Catalog for MIR4499 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4499 Gene

Localization for MIR4499 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4499 Gene

Pathways & Interactions for MIR4499 Gene

SuperPathways for MIR4499 Gene

No Data Available

Interacting Proteins for MIR4499 Gene

Gene Ontology (GO) - Biological Process for MIR4499 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4499 Gene

Drugs & Compounds for MIR4499 Gene

No Compound Related Data Available

Transcripts for MIR4499 Gene

mRNA/cDNA for MIR4499 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4499 Gene

No ASD Table

Relevant External Links for MIR4499 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4499 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4499 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4499 Gene:

genes like me logo Genes that share expression patterns with MIR4499: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4499 Gene

Orthologs for MIR4499 Gene

Evolution for MIR4499 Gene

Gene Tree for MIR4499 (if available)
Gene Tree for MIR4499 (if available)

No data available for Orthologs for MIR4499 Gene

Paralogs for MIR4499 Gene

No data available for Paralogs for MIR4499 Gene

Variants for MIR4499 Gene

Sequence variations from dbSNP and Humsavar for MIR4499 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1005536975 -- 20,434,388(-) G/C/T upstream_transcript_variant
rs1005653400 -- 20,434,641(-) C/T upstream_transcript_variant
rs1006506002 -- 20,434,070(-) T/C upstream_transcript_variant
rs1006897641 -- 20,433,637(-) G/T downstream_transcript_variant
rs1007107103 -- 20,434,316(-) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4499 Gene

Variant ID Type Subtype PubMed ID
nsv818947 CNV loss 17921354
nsv1151909 OTHER inversion 26484159
nsv1140246 OTHER inversion 24896259
nsv1078303 OTHER inversion 25765185
nsv1046946 CNV gain 25217958
esv3892302 CNV loss 25118596
esv3892301 CNV loss 25118596
esv34984 CNV loss 17911159
esv2759925 CNV loss 17122850
esv2751132 CNV loss 17911159
dgv3075n54 CNV loss 21841781
dgv3072n54 CNV loss 21841781
dgv221n27 CNV loss 19166990
dgv1612n100 CNV loss 25217958

Additional Variant Information for MIR4499 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4499 Gene

Disorders for MIR4499 Gene

Additional Disease Information for MIR4499

No disorders were found for MIR4499 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4499 Gene

Publications for MIR4499 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4499 Gene

Sources for MIR4499 Gene

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