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Aliases for MIR4498 Gene

Subcategory (RNA class) for MIR4498 Gene


Quality Score for this RNA gene is


Aliases for MIR4498 Gene

  • MicroRNA 4498 2 3 5
  • Hsa-Mir-4498 3
  • Mir-4498 3

External Ids for MIR4498 Gene

Previous GeneCards Identifiers for MIR4498 Gene

  • GC12U901601
  • GC12M120595

Summaries for MIR4498 Gene

Entrez Gene Summary for MIR4498 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4498 Gene

MIR4498 (MicroRNA 4498) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4498 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4498 Gene

Genomics for MIR4498 Gene

GeneHancer (GH) Regulatory Elements for MIR4498 Gene

Promoters and enhancers for MIR4498 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I120115 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.3 +36.5 36464 7.5 HDGF PKNOX1 CLOCK SMAD1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 IRF4 RAB35 GCN1 PXN-AS1 RPLP0 PXN COQ5 ENSG00000277283 MIR4498
GH12I120125 Enhancer 1 Ensembl ENCODE dbSUPER 0.3 +28.6 28644 2.2 PKNOX1 RFX1 JUN MAX EBF1 BMI1 CTBP1 POLR2A SCRT2 KDM1A PXN-AS1 RPLP0 GCN1 PXN RAB35 MIR4498
GH12I120131 Enhancer 0.9 ENCODE dbSUPER 0.3 +22.8 22833 2.7 BACH1 EBF1 BMI1 IRF4 RELA ZFHX2 POLR2A ZNF143 ATF7 BCLAF1 GCN1 COQ5 RAB35 MIR4498
GH12I120136 Enhancer 0.6 ENCODE 0.4 +19.0 18987 0.1 SMARCE1 PAF1 ESRRA DPF2 MNT E2F1 ZNF217 CTBP1 GATA3 CREB1 RAB35 MIR4498 GCN1
GH12I120181 Enhancer 0.8 ENCODE 0.3 -27.1 -27103 2 PKNOX1 BATF RFX5 ZNF335 ZNF362 NFYC CEBPB ZEB2 TSHZ1 TGIF2 PXN GCN1 MIR4498
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4498 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4498 Gene

Genomic Locations for MIR4498 Gene
66 bases
Minus strand

Genomic View for MIR4498 Gene

Genes around MIR4498 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4498 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4498 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4498 Gene

ORGUL Member Location for MIR4498 Gene

ORGUL Member Location for MIR4498 gene

Proteins for MIR4498 Gene

Post-translational modifications for MIR4498 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4498 Gene

Domains & Families for MIR4498 Gene

Gene Families for MIR4498 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4498: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4498 Gene

Function for MIR4498 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4498 Gene

Localization for MIR4498 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4498 Gene

Pathways & Interactions for MIR4498 Gene

SuperPathways for MIR4498 Gene

No Data Available

Interacting Proteins for MIR4498 Gene

Gene Ontology (GO) - Biological Process for MIR4498 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4498 Gene

Drugs & Compounds for MIR4498 Gene

No Compound Related Data Available

Transcripts for MIR4498 Gene

mRNA/cDNA for MIR4498 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4498 Gene

No ASD Table

Relevant External Links for MIR4498 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4498 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4498 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4498 Gene

Orthologs for MIR4498 Gene

Evolution for MIR4498 Gene

Gene Tree for MIR4498 (if available)
Gene Tree for MIR4498 (if available)

No data available for Orthologs for MIR4498 Gene

Paralogs for MIR4498 Gene

No data available for Paralogs for MIR4498 Gene

Variants for MIR4498 Gene

Sequence variations from dbSNP and Humsavar for MIR4498 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1002455228 -- 120,157,184(-) C/T upstream_transcript_variant
rs1003859594 -- 120,157,137(-) A/G upstream_transcript_variant
rs1003892091 -- 120,156,913(-) T/C upstream_transcript_variant
rs1005891351 -- 120,156,233(-) C/T upstream_transcript_variant
rs1008069954 -- 120,156,375(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4498 Gene

Variant ID Type Subtype PubMed ID
nsv519657 CNV loss 19592680
nsv560433 CNV loss 21841781
nsv832530 CNV loss 17160897

Additional Variant Information for MIR4498 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4498 Gene

Disorders for MIR4498 Gene

Additional Disease Information for MIR4498

No disorders were found for MIR4498 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4498 Gene

Publications for MIR4498 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4498 Gene

Sources for MIR4498 Gene

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