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Aliases for MIR4494 Gene

Subcategory (RNA class) for MIR4494 Gene


Quality Score for this RNA gene is


Aliases for MIR4494 Gene

  • MicroRNA 4494 2 3 5
  • Hsa-Mir-4494 3

External Ids for MIR4494 Gene

Previous GeneCards Identifiers for MIR4494 Gene

  • GC12U901596
  • GC12M047759

Summaries for MIR4494 Gene

Entrez Gene Summary for MIR4494 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4494 Gene

MIR4494 (MicroRNA 4494) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4494 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4494 Gene

Genomics for MIR4494 Gene

GeneHancer (GH) Regulatory Elements for MIR4494 Gene

Promoters and enhancers for MIR4494 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I047359 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.8 +2.9 2863 3.2 SMAD1 ATF1 ARNT TCF12 ZNF766 GATA2 NCOA1 REST ZNF592 ATF4 PCED1B HDAC7 MIR4494 LINC02416
GH12I047354 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +8.1 8089 2.4 HDAC1 MEIS2 TEAD4 TAL1 MAX CEBPG BATF TCF12 CTBP1 NFATC1 LINC02416 MIR4494
GH12I047376 Enhancer 1.2 Ensembl ENCODE 0.4 -14.0 -14018 2.7 FOXA2 PKNOX1 ATF1 ARNT SIN3A YY1 TCF12 ZNF766 FOS ATF7 ENSG00000199566 AMIGO2 LINC02416 PCED1B MIR4494 LINC02156
GH12I047392 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -29.4 -29366 1.7 HDAC1 PKNOX1 ARNT FEZF1 ZNF121 ZNF398 ZEB2 NFIC ZNF184 SMARCA4 ENSG00000199566 AMIGO2 LINC02156 MIR4494
GH12I047396 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.3 -33.3 -33344 1.6 CTCF FOXA2 SIN3A RAD21 YY1 CC2D1A ARID2 FOXK2 BRD9 SMC3 ENSG00000199566 AMIGO2 SLC38A4 PFKM LINC02156 MIR4494
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4494 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4494 Gene

Genomic Locations for MIR4494 Gene
84 bases
Minus strand

Genomic View for MIR4494 Gene

Genes around MIR4494 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4494 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4494 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4494 Gene

Proteins for MIR4494 Gene

Post-translational modifications for MIR4494 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4494 Gene

Domains & Families for MIR4494 Gene

Gene Families for MIR4494 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4494: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4494 Gene

Function for MIR4494 Gene

Phenotypes From GWAS Catalog for MIR4494 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4494 Gene

Localization for MIR4494 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4494 Gene

Pathways & Interactions for MIR4494 Gene

SuperPathways for MIR4494 Gene

No Data Available

Interacting Proteins for MIR4494 Gene

Gene Ontology (GO) - Biological Process for MIR4494 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4494 Gene

Drugs & Compounds for MIR4494 Gene

No Compound Related Data Available

Transcripts for MIR4494 Gene

mRNA/cDNA for MIR4494 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4494 Gene

No ASD Table

Relevant External Links for MIR4494 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4494 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4494 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4494 Gene:

genes like me logo Genes that share expression patterns with MIR4494: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4494 Gene

Orthologs for MIR4494 Gene

Evolution for MIR4494 Gene

Gene Tree for MIR4494 (if available)
Gene Tree for MIR4494 (if available)

No data available for Orthologs for MIR4494 Gene

Paralogs for MIR4494 Gene

No data available for Paralogs for MIR4494 Gene

Variants for MIR4494 Gene

Sequence variations from dbSNP and Humsavar for MIR4494 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1002151046 -- 47,365,045(-) C/T upstream_transcript_variant
rs1002503501 -- 47,364,753(-) T/G upstream_transcript_variant
rs1003164192 -- 47,364,811(-) G/A upstream_transcript_variant
rs1003449290 -- 47,364,578(-) A/G upstream_transcript_variant
rs1004851602 -- 47,366,151(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4494 Gene

Variant ID Type Subtype PubMed ID
esv3892198 CNV gain 25118596
nsv558785 CNV gain 21841781

Additional Variant Information for MIR4494 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4494 Gene

Disorders for MIR4494 Gene

Additional Disease Information for MIR4494

No disorders were found for MIR4494 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4494 Gene

Publications for MIR4494 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4494 Gene

Sources for MIR4494 Gene

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