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Aliases for MIR4490 Gene

Subcategory (RNA class) for MIR4490 Gene


Quality Score for this RNA gene is


Aliases for MIR4490 Gene

  • MicroRNA 4490 2 3 5
  • Hsa-Mir-4490 3

External Ids for MIR4490 Gene

Previous GeneCards Identifiers for MIR4490 Gene

  • GC11U901883
  • GC11M090290

Summaries for MIR4490 Gene

Entrez Gene Summary for MIR4490 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4490 Gene

MIR4490 (MicroRNA 4490) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4490 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4490 Gene

Genomics for MIR4490 Gene

Genomic Locations for MIR4490 Gene

Genomic Locations for MIR4490 Gene
84 bases
Minus strand

Genomic View for MIR4490 Gene

Genes around MIR4490 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4490 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4490 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4490 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR4490 Gene

Proteins for MIR4490 Gene

Post-translational modifications for MIR4490 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4490 Gene

Domains & Families for MIR4490 Gene

Gene Families for MIR4490 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4490: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4490 Gene

Function for MIR4490 Gene

Phenotypes From GWAS Catalog for MIR4490 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4490 Gene

Localization for MIR4490 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4490 Gene

Pathways & Interactions for MIR4490 Gene

SuperPathways for MIR4490 Gene

No Data Available

Interacting Proteins for MIR4490 Gene

Gene Ontology (GO) - Biological Process for MIR4490 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4490 Gene

Drugs & Compounds for MIR4490 Gene

No Compound Related Data Available

Transcripts for MIR4490 Gene

mRNA/cDNA for MIR4490 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4490 Gene

No ASD Table

Relevant External Links for MIR4490 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4490 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4490 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4490 Gene

Orthologs for MIR4490 Gene

Evolution for MIR4490 Gene

Gene Tree for MIR4490 (if available)
Gene Tree for MIR4490 (if available)

No data available for Orthologs for MIR4490 Gene

Paralogs for MIR4490 Gene

No data available for Paralogs for MIR4490 Gene

Variants for MIR4490 Gene

Sequence variations from dbSNP and Humsavar for MIR4490 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000445892 -- 90,556,334(-) G/A upstream_transcript_variant
rs1001186193 -- 90,557,639(-) G/A upstream_transcript_variant
rs1001229487 -- 90,557,208(-) C/G upstream_transcript_variant
rs1004201615 -- 90,557,845(-) A/T upstream_transcript_variant
rs1006651121 -- 90,555,923(-) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4490 Gene

Variant ID Type Subtype PubMed ID
nsv1053196 CNV loss 25217958
nsv1048624 CNV loss 25217958
nsv1039065 CNV gain 25217958
esv3892063 CNV loss 25118596
esv3892062 CNV loss 25118596
esv3627209 CNV loss 21293372
esv3579993 CNV gain 25503493

Additional Variant Information for MIR4490 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4490 Gene

Disorders for MIR4490 Gene

Additional Disease Information for MIR4490

No disorders were found for MIR4490 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4490 Gene

Publications for MIR4490 Gene

  1. A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. (PMID: 25130324) Cai DC … Hagoort P (Genes, brain, and behavior 2014) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4490 Gene

Sources for MIR4490 Gene

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