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Aliases for MIR4488 Gene

Subcategory (RNA class) for MIR4488 Gene


Quality Score for this RNA gene is


Aliases for MIR4488 Gene

  • MicroRNA 4488 2 3 5
  • Hsa-Mir-4488 3
  • Mir-4488 3

External Ids for MIR4488 Gene

Previous GeneCards Identifiers for MIR4488 Gene

  • GC11U901857
  • GC11P061280

Summaries for MIR4488 Gene

Entrez Gene Summary for MIR4488 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4488 Gene

MIR4488 (MicroRNA 4488) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4488 include Behcet Syndrome.

Additional gene information for MIR4488 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4488 Gene

Genomics for MIR4488 Gene

GeneHancer (GH) Regulatory Elements for MIR4488 Gene

Promoters and enhancers for MIR4488 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I061507 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 0.8 +3.2 3229 8 PKNOX1 ARID4B SIN3A ZNF2 ZNF48 GLIS2 CBX5 E2F8 ZNF143 FOS LRRC10B SYT7 TMEM216 DDB1 TKFC MIR4488 ENSG00000279878
GH11I061498 Enhancer 0.8 FANTOM5 0.4 -9.6 -9591 0.3 NFATC3 TAF9B TEAD4 CDC5L ZBTB40 E4F1 POLR2B MTA3 POLR2A EGR1 TMEM138 CPSF7 DDB1 TKFC LRRC10B LOC105369329 MIR4488
GH11I061499 Enhancer 0.4 ENCODE 0.4 -8.3 -8286 0.7 POLR2A POU5F1 CTBP2 DDB1 TKFC LOC105369329 MIR4488
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4488 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4488 Gene

Genomic Locations for MIR4488 Gene
62 bases
Plus strand

Genomic View for MIR4488 Gene

Genes around MIR4488 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4488 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4488 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4488 Gene

Proteins for MIR4488 Gene

Post-translational modifications for MIR4488 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4488 Gene

Domains & Families for MIR4488 Gene

Gene Families for MIR4488 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4488: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4488 Gene

Function for MIR4488 Gene

Phenotypes From GWAS Catalog for MIR4488 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4488 Gene

Localization for MIR4488 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4488 Gene

Pathways & Interactions for MIR4488 Gene

SuperPathways for MIR4488 Gene

No Data Available

Interacting Proteins for MIR4488 Gene

Gene Ontology (GO) - Biological Process for MIR4488 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4488 Gene

Drugs & Compounds for MIR4488 Gene

No Compound Related Data Available

Transcripts for MIR4488 Gene

mRNA/cDNA for MIR4488 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4488 Gene

No ASD Table

Relevant External Links for MIR4488 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4488 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4488 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4488 Gene

Orthologs for MIR4488 Gene

Evolution for MIR4488 Gene

Gene Tree for MIR4488 (if available)
Gene Tree for MIR4488 (if available)

No data available for Orthologs for MIR4488 Gene

Paralogs for MIR4488 Gene

No data available for Paralogs for MIR4488 Gene

Variants for MIR4488 Gene

Sequence variations from dbSNP and Humsavar for MIR4488 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1002140019 -- 61,508,629(+) T/C non_coding_transcript_variant
rs1003274709 -- 61,508,760(+) G/A/C downstream_transcript_variant
rs1003287241 -- 61,507,310(+) C/T upstream_transcript_variant
rs1003589247 -- 61,508,565(+) T/G upstream_transcript_variant
rs1005107821 -- 61,506,716(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4488 Gene

Variant ID Type Subtype PubMed ID
dgv1962n54 CNV loss 21841781
nsv1070462 CNV deletion 25765185
nsv468582 CNV loss 19166990
nsv555167 CNV loss 21841781
nsv555168 CNV loss 21841781
nsv825938 CNV gain 20364138
nsv832178 CNV gain+loss 17160897

Additional Variant Information for MIR4488 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4488 Gene

Disorders for MIR4488 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR4488 Gene - From: DISEASES

Disorder Aliases PubMed IDs
behcet syndrome
  • behcet disease; bd
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR4488

genes like me logo Genes that share disorders with MIR4488: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4488 Gene

Publications for MIR4488 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4488 Gene

Sources for MIR4488 Gene

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