microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4482 Gene

Data sources for MIR4482 Gene:

RNA type for MIR4482 Gene

miRNA

Aliases for MIR4482 Gene

External Ids for MIR4482 Gene

Previous HGNC Symbols for MIR4482 Gene

  • MIR4482-1

Previous GeneCards Identifiers for MIR4482 Gene

  • GC10U901558
  • GC10M106034

Summaries for MIR4482 Gene

Entrez Gene Summary for MIR4482 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4482 Gene

MIR4482 (MicroRNA 4482) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4482 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4482 Gene

Genomics for MIR4482 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4482 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J104267 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -0.3 -260 3.1 SP1 ZNF207 POLR2A ATF3 BRCA1 YY1 CTCF CEBPB SIN3A ETS1 GSTO2 MIR4482 lnc-CFAP43-4 MN297008 CFAP43 GSTO1 PDCD11 PCGF6 CFAP58-DT CFAP58
GH10J103810 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.2 +455.5 455480 5.4 ZIC2 YY1 RXRA SAP130 JUND HNF4A RAD21 NR2F6 MAX MAFK GSTO1 MIR4482 SH3PXD2A SH3PXD2A-AS1 NEURL1
GH10J105148 Enhancer 0.3 Ensembl ENCODE 5.4 -881.1 -881117 2.2 MIR4482 lnc-ITPRIP-7 piR-36588-051 SORCS3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4482 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4482 Gene

Latest Assembly
chr10:104,268,336-104,268,405
(GRCh38/hg38)
Size:
70 bases
Orientation:
Minus strand

Previous Assembly
chr10:106,028,094-106,028,163
(GRCh37/hg19 by Entrez Gene)
Size:
70 bases
Orientation:
Minus strand

chr10:106,028,080-106,028,177
(GRCh37/hg19 by Ensembl)
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR4482 Gene

Genes around MIR4482 on UCSC Golden Path with GeneCards custom track
MIR4482 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4482 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4482 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4482 Gene

Proteins for MIR4482 Gene

Post-translational modifications for MIR4482 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4482 Gene

Domains & Families for MIR4482 Gene

Gene Families for MIR4482 Gene

HGNC:
genes like me logo Genes that share domains with MIR4482: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4482 Gene

Function for MIR4482 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4482 Gene

Localization for MIR4482 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4482 Gene

Pathways & Interactions for MIR4482 Gene

PathCards logo

SuperPathways for MIR4482 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4482 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4482 Gene

Drugs & Compounds for MIR4482 Gene

No Compound Related Data Available

Transcripts for MIR4482 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4482 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075A962_9606 miRNA 22 4

RefSeq: NR_039702,

LncBase: hsa-miR-4482-5p,

miRBase: MIMAT0019016,

TarBase: hsa-miR-4482-5p,

URS000075F0D2_9606 precursor_RNA 70 3

RefSeq: NR_039702,

Ensembl: ENST00000583050 (view in UCSC) ,

miRBase: MI0016843,

URS000075E237_9606 miRNA 22 2

RefSeq: NR_039702,

miRBase: MIMAT0020958,

MIR4482 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4482 Gene

No ASD Table

Relevant External Links for MIR4482 Gene

GeneLoc Exon Structure for
MIR4482

No data available for mRNA/cDNA for MIR4482 Gene

Expression for MIR4482 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4482 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4482

genes like me logo Genes that share expression patterns with MIR4482: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4482 Gene

Orthologs for MIR4482 Gene

Evolution for MIR4482 Gene

ENSEMBL:
Gene Tree for MIR4482 (if available)
TreeFam:
Gene Tree for MIR4482 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4482

No data available for Orthologs for MIR4482 Gene

Paralogs for MIR4482 Gene

No data available for Paralogs for MIR4482 Gene

Variants for MIR4482 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4482 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4482 Gene

Variant ID Type Subtype PubMed ID
nsv1039166 CNV loss 25217958
nsv552062 CNV loss 21841781
nsv831971 CNV gain 17160897

Additional Variant Information for MIR4482 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4482
Leiden Open Variation Database (LOVD)
MIR4482

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4482 Gene

Disorders for MIR4482 Gene

Additional Disease Information for MIR4482

No disorders were found for MIR4482 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4482 Gene

Publications for MIR4482 Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3
  2. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N … Zhou G (Journal of radiation research 2011) 3
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4482 Gene

Sources for MIR4482 Gene