Aliases for MIR4481 Gene
Subcategory (RNA class) for MIR4481 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR4481 Gene
- HGNC: 41781
- Entrez Gene: 100616320
- Ensembl: ENSG00000283699
- miRBase: hsa-mir-4481
ORGUL Members for MIR4481 Gene
Previous GeneCards Identifiers for MIR4481 Gene
- GC10U901561
Summaries for MIR4481 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4481 Gene
MIR4481 (MicroRNA 4481) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR4481 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4481 Gene
Genomics for MIR4481 Gene
GeneHancer (GH) Regulatory Elements for MIR4481 Gene
Promoters and enhancers for MIR4481 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10I012656 | Enhancer | 0.6 | ENCODE | 0.8 | -3.5 | -3530 | 0.2 | CTCF ZNF654 TRIM22 ZNF140 REST ZNF501 RAD21 ZSCAN21 KLF16 SMC3 | SEPHS1 ENSG00000228302 ENSG00000239665 CAMK1D MIR548Q CCDC3 OPTN MIR4481 GC10P012703 | |
| GH10I012637 | Enhancer | 0.7 | Ensembl ENCODE | 0.4 | +14.9 | 14932 | 0.9 | ZNF664 KLF1 MAZ ZNF341 ZNF600 ZIC2 ZBTB17 | MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481 | |
| GH10I012631 | Enhancer | 0.7 | ENCODE | 0.3 | +21.2 | 21240 | 0.1 | ELF3 PKNOX1 FOXA2 RXRA SAP130 FOXA3 CHD1 MNT ZNF48 RAD21 | MIR548Q CAMK1D OPTN CCDC3 GC10M012628 MIR4481 | |
| GH10I012698 | Enhancer | 0.9 | Ensembl ENCODE | 0.2 | -46.4 | -46392 | 1.6 | MAX ZNF384 RAD21 YY1 ZFHX2 EGR2 RXRA HLF REST ZBTB5 | MIR548Q OPTN CCDC3 GC10P012703 MIR4481 CAMK1D | |
| GH10I012632 | Enhancer | 0.6 | ENCODE | 0.3 | +20.7 | 20662 | 0.8 | ELF3 TFAP4 PKNOX1 MNT ZNF48 YY1 SP1 JUND ATF3 ZNF341 | MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR4481 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR4481 Gene
Genomic Locations for MIR4481 Gene
- chr10:12,653,138-12,653,197
- (GRCh38/hg38)
- Size:
- 60 bases
- Orientation:
- Minus strand
- chr10:12,695,137-12,695,196
- (GRCh37/hg19)
Genomic View for MIR4481 Gene
Genes around MIR4481 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10p13 by Ensembl
- 10p13 by Entrez Gene
- 10p13 by HGNC
MIR4481 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4481 Gene
Proteins for MIR4481 Gene
Post-translational modifications for MIR4481 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4481
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4481
- Origene Custom Protein Services for MIR4481
- Search GeneTex for Proteins for MIR4481
No data available for DME Specific Peptides for MIR4481 Gene
Domains & Families for MIR4481 Gene
Gene Families for MIR4481 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4481 Gene
Function for MIR4481 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4481
-
- Search ViGene Biosciences for MIR4481
CRISPR Products
- Browse CRISPR knockouts for MIR4481
- Applied Biological Materials CRISPR for MIR4481
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4481
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4481
- VectorBuilder custom plasmid, inducible vectors for MIR4481
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4481
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR4481
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4481 Gene
Localization for MIR4481 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4481 Gene
Transcripts for MIR4481 Gene
mRNA/cDNA for MIR4481 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4481
- Applied Biological Materials CRISPR for MIR4481
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4481
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4481
- VectorBuilder custom plasmid, inducible vectors for MIR4481
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4481
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR4481
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR4481 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4481 Gene:
MIR4481
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4481 Gene
Orthologs for MIR4481 Gene
No data available for Orthologs for MIR4481 Gene
Paralogs for MIR4481 Gene
No data available for Paralogs for MIR4481 Gene
Variants for MIR4481 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1004546158 | -- | 12,653,951(-) | G/A | upstream_transcript_variant | |
| rs1004778479 | -- | 12,654,502(-) | A/G | upstream_transcript_variant | |
| rs1006261907 | -- | 12,652,891(-) | G/A | downstream_transcript_variant | |
| rs1006463369 | -- | 12,653,228(-) | A/T | upstream_transcript_variant | |
| rs1007670538 | -- | 12,653,815(-) | A/G | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3622363 | CNV | gain | 21293372 |
| nsv1041648 | CNV | gain | 25217958 |
| nsv831786 | CNV | loss | 17160897 |
Additional Variant Information for MIR4481 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4481
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4481 Gene
Disorders for MIR4481 Gene
Additional Disease Information for MIR4481
No disorders were found for MIR4481 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4481 Gene
Publications for MIR4481 Gene
- Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR4481 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4481
- Origene Custom Protein Services for MIR4481
- Browse OriGene Inhibitory RNA Products For MIR4481
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4481
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR4481
- GenScript: Custom all cDNA clones Services for MIR4481
- GenScript Custom Purified and Recombinant Proteins Services for MIR4481
- GenScript Custom Assay Services for MIR4481
- GenScript Custom overexpressing Cell Line Services for MIR4481
- Browse GenScript CRISPR for MIR4481
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR4481
- Browse Sino Biological cDNA Clones
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4481
- VectorBuilder custom plasmid, inducible vectors for MIR4481
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4481
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR4481
- Search GeneTex for Proteins for MIR4481
- Search ViGene Biosciences for MIR4481
Sources for MIR4481 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
