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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR4480 Gene
Subcategory (RNA class) for MIR4480 Gene
miRNA
Number of RNA Genes sources:
1 / 17
Aliases for MIR4480 Gene
External Ids for MIR4480 Gene
- HGNC: 41716
- Entrez Gene: 100616151
- Ensembl: ENSG00000263584
- miRBase: hsa-mir-4480
Previous GeneCards Identifiers for MIR4480 Gene
- GC10U901537
- GC10P012622
Summaries for MIR4480 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4480 Gene
MIR4480 (MicroRNA 4480) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR4480 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4480 Gene
Genomics for MIR4480 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR4480 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10J012579 | Enhancer | 0.8 | Ensembl ENCODE dbSUPER | 600.7 | +1.4 | 1447 | 1.2 | SP1 ZBTB40 RAD21 HNF4A | MIR4480 CAMK1D RF00017-588 OPTN | |
| GH10J012587 | Enhancer | 0.6 | ENCODE dbSUPER | 0.4 | +10.2 | 10220 | 1.6 | FOXA1 EED RUNX3 KLF4 FOS TCF7L2 | RF00017-588 MIR4480 CAMK1D OPTN | |
| GH10J012564 | Enhancer | 0.5 | Ensembl | 0.4 | -14.5 | -14453 | 1 | JUND RUNX3 ZBTB40 FOS JUNB BATF ATF2 | ENSG00000285994 CAMK1D MIR548Q MIR4480 OPTN | |
| GH10J012586 | Enhancer | 0.4 | dbSUPER | 0.4 | +8.1 | 8064 | 0.7 | ZNF184 ZNF362 ZSCAN21 ZEB2 | RF00017-588 MIR4480 CAMK1D OPTN | |
| GH10J012592 | Enhancer | 0.5 | dbSUPER | 0.4 | +12.7 | 12665 | 0.7 | SP1 YY1 RAD21 RXRA HNF4A | RF00017-588 MIR4480 CAMK1D OPTN |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR4480 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR4480 Gene
Genomic Locations for MIR4480 Gene
- chr10:12,578,753-12,578,823
- (GRCh38/hg38)
- Size:
- 71 bases
- Orientation:
- Plus strand
- chr10:12,620,752-12,620,822
- (GRCh37/hg19)
- Size:
- 71 bases
- Orientation:
- Plus strand
Genomic View for MIR4480 Gene
Genes around MIR4480 on UCSC Golden Path with GeneCards custom track
MIR4480 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 10p13 by HGNC
- 10p13 by Entrez Gene
- 10p13 by Ensembl
MIR4480 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4480 Gene
Proteins for MIR4480 Gene
Post-translational modifications for MIR4480 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4480
- Origene Custom Protein Services for MIR4480
No data available for DME Specific Peptides for MIR4480 Gene
Domains & Families for MIR4480 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4480 Gene
Function for MIR4480 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR4480 - Select products 50% OFF >
- * MIR4480 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR4480
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR4480 - Select products 50% OFF >
- * MIR4480 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4480 Gene
Localization for MIR4480 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4480 Gene
Transcripts for MIR4480 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4480 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS0000759B95_9606 | precursor_RNA | 71 | 4 |
HGNC: 41716, RefSeq: NR_039700, Ensembl: ENST00000582492 (view in UCSC) , miRBase: MI0016841, |
| URS000075AC09_9606 | miRNA | 21 | 2 |
RefSeq: NR_039700, miRBase: MIMAT0019014, |
MIR4480 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR4480 - Select products 50% OFF >
- * MIR4480 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR4480
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR4480 - Select products 50% OFF >
- * MIR4480 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for MIR4480 Gene
- GeneLoc Exon Structure for
- MIR4480
No data available for mRNA/cDNA for MIR4480 Gene
Expression for MIR4480 Gene
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4480 Gene
Orthologs for MIR4480 Gene
No data available for Orthologs for MIR4480 Gene
Paralogs for MIR4480 Gene
No data available for Paralogs for MIR4480 Gene
Variants for MIR4480 Gene
Additional Variant Information for MIR4480 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4480
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4480 Gene
Disorders for MIR4480 Gene
Additional Disease Information for MIR4480
No disorders were found for MIR4480 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4480 Gene
Publications for MIR4480 Gene
- Brain metastasis-related microRNAs in patients with advanced breast cancer. (PMID: 31603918) Sato J … Tamura K (PloS one 2019) 3
- Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
ExternalLinks
Products for MIR4480 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4480
- Origene Custom Protein Services for MIR4480
- Browse OriGene Inhibitory RNA Products For MIR4480
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4480
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR4480
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR4480
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR4480
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR4480
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR4480
Sources for MIR4480 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB