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Aliases for MIR4470 Gene

Subcategory (RNA class) for MIR4470 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4470 Gene

  • MicroRNA 4470 2 3 5
  • Hsa-Mir-4470 3
  • Mir-4470 3

External Ids for MIR4470 Gene

Previous GeneCards Identifiers for MIR4470 Gene

  • GC08U901576
  • GC08P062629

Summaries for MIR4470 Gene

Entrez Gene Summary for MIR4470 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4470 Gene

MIR4470 (MicroRNA 4470) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4470 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4470 Gene

Genomics for MIR4470 Gene

GeneHancer (GH) Regulatory Elements for MIR4470 Gene

Promoters and enhancers for MIR4470 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I061706 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 -3.1 -3121 10.2 HDGF PKNOX1 CLOCK FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ASPH NPM1P6 MIR4470 GC08P061662
GH08I061717 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +6.0 6016 7 PKNOX1 SIN3A FOS CAVIN1 REST ZNF592 SREBF1 MAFF SMARCA4 STAT3 ASPH MIR4470 ENSG00000251127
GH08I061733 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +19.7 19695 2.7 HDAC1 ELF3 PKNOX1 CLOCK FOXA2 NEUROD1 ZBTB40 RCOR1 FOS CEBPB ASPH MIR4470 ENSG00000251127
GH08I061724 Enhancer 0.9 ENCODE dbSUPER 0.4 +10.2 10159 0.2 SOX13 CTCF SAP130 RAD21 GATA3 BRD9 GATAD2A SOX5 ZNF654 SOX6 MIR4470 ENSG00000251127
GH08I061731 Enhancer 0.8 FANTOM5 ENCODE 0.4 +17.0 16969 0.2 MEIS2 RFX1 RNF2 ETV1 GABPA POLR2A IKZF1 ETV6 NR2C2 ASPH MIR4470 ENSG00000251127
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4470 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4470 Gene

Genomic Locations for MIR4470 Gene
chr8:61,714,788-61,714,859
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr8:62,627,347-62,627,418
(GRCh37/hg19)

Genomic View for MIR4470 Gene

Genes around MIR4470 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4470 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4470 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4470 Gene

Proteins for MIR4470 Gene

Post-translational modifications for MIR4470 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4470 Gene

Domains & Families for MIR4470 Gene

Gene Families for MIR4470 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4470: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4470 Gene

Function for MIR4470 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4470 Gene

Localization for MIR4470 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4470 Gene

Pathways & Interactions for MIR4470 Gene

SuperPathways for MIR4470 Gene

No Data Available

Interacting Proteins for MIR4470 Gene

Gene Ontology (GO) - Biological Process for MIR4470 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4470 Gene

Drugs & Compounds for MIR4470 Gene

No Compound Related Data Available

Transcripts for MIR4470 Gene

mRNA/cDNA for MIR4470 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4470 Gene

No ASD Table

Relevant External Links for MIR4470 Gene

GeneLoc Exon Structure for
MIR4470
ECgene alternative splicing isoforms for
MIR4470

Expression for MIR4470 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4470 Gene:

MIR4470
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4470 Gene

Orthologs for MIR4470 Gene

Evolution for MIR4470 Gene

ENSEMBL:
Gene Tree for MIR4470 (if available)
TreeFam:
Gene Tree for MIR4470 (if available)

No data available for Orthologs for MIR4470 Gene

Paralogs for MIR4470 Gene

No data available for Paralogs for MIR4470 Gene

Variants for MIR4470 Gene

Sequence variations from dbSNP and Humsavar for MIR4470 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000198382 -- 61,713,919(+) G/A upstream_transcript_variant
rs1001166968 -- 61,714,481(+) G/A upstream_transcript_variant
rs1001438182 -- 61,714,650(+) T/C upstream_transcript_variant
rs1002489695 -- 61,713,699(+) T/C upstream_transcript_variant
rs1004070334 -- 61,713,324(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4470 Gene

Variant ID Type Subtype PubMed ID
esv2761430 CNV loss 21179565
esv3617393 CNV gain 21293372
nsv1015216 CNV loss 25217958

Additional Variant Information for MIR4470 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4470

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4470 Gene

Disorders for MIR4470 Gene

Additional Disease Information for MIR4470

No disorders were found for MIR4470 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4470 Gene

Publications for MIR4470 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4470 Gene

Sources for MIR4470 Gene

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