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Aliases for MIR4463 Gene

Subcategory (RNA class) for MIR4463 Gene


Quality Score for this RNA gene is


Aliases for MIR4463 Gene

  • MicroRNA 4463 2 3 5
  • Hsa-Mir-4463 3

External Ids for MIR4463 Gene

Previous GeneCards Identifiers for MIR4463 Gene

  • GC06U902222
  • GC06P076140

Summaries for MIR4463 Gene

Entrez Gene Summary for MIR4463 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4463 Gene

MIR4463 (MicroRNA 4463) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4463 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4463 Gene

Genomics for MIR4463 Gene

GeneHancer (GH) Regulatory Elements for MIR4463 Gene

Promoters and enhancers for MIR4463 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I075429 Enhancer 0.3 dbSUPER 550.8 +1.1 1132 0.9 PRDM6 MIR4463 RNU1-34P FILIP1 RPL26P20 PIR50339 GC06P075402 LOC101928540
GH06I075426 Enhancer 0.2 dbSUPER 550.8 -1.7 -1674 0.8 MIR4463 FILIP1 GC06P075402 LOC101928540
GH06I075430 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.8 +3.1 3086 2.1 RFX1 JUN GFI1B ZNF398 ZEB2 ZSCAN21 JUND SCRT2 PRDM10 FOS FILIP1 RNU1-34P RPL26P20 SENP6 MIR4463 PIR50339 GC06P075402 LOC101928540
GH06I075425 Enhancer 0.6 ENCODE 0.8 -3.1 -3067 0.1 RFX1 JUN ZNF843 OSR2 JUND PRDM6 IKZF1 FOXP2 ZBTB33 FOS MIR4463 GC06P075402 LOC101928540 FILIP1
GH06I075413 Enhancer 1.1 ENCODE dbSUPER 0.4 -14.8 -14832 1 FEZF1 KLF7 FOS KLF13 REST TSHZ1 ZNF488 GLIS1 STAT3 PRDM4 SENP6 MIR4463 GC06P075402 LOC101928540 FILIP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4463 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4463 Gene

Genomic Locations for MIR4463 Gene
67 bases
Plus strand

Genomic View for MIR4463 Gene

Genes around MIR4463 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4463 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4463 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4463 Gene

Proteins for MIR4463 Gene

Post-translational modifications for MIR4463 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4463 Gene

Domains & Families for MIR4463 Gene

Gene Families for MIR4463 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4463: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4463 Gene

Function for MIR4463 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4463 Gene

Localization for MIR4463 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4463 Gene

Pathways & Interactions for MIR4463 Gene

SuperPathways for MIR4463 Gene

No Data Available

Interacting Proteins for MIR4463 Gene

Gene Ontology (GO) - Biological Process for MIR4463 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4463 Gene

Drugs & Compounds for MIR4463 Gene

No Compound Related Data Available

Transcripts for MIR4463 Gene

mRNA/cDNA for MIR4463 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4463 Gene

No ASD Table

Relevant External Links for MIR4463 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4463 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4463 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4463 Gene:

genes like me logo Genes that share expression patterns with MIR4463: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4463 Gene

Orthologs for MIR4463 Gene

Evolution for MIR4463 Gene

Gene Tree for MIR4463 (if available)
Gene Tree for MIR4463 (if available)

No data available for Orthologs for MIR4463 Gene

Paralogs for MIR4463 Gene

No data available for Paralogs for MIR4463 Gene

Variants for MIR4463 Gene

Sequence variations from dbSNP and Humsavar for MIR4463 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000954748 -- 75,426,728(+) A/C upstream_transcript_variant
rs1001596022 -- 75,426,782(+) C/T upstream_transcript_variant
rs1001710642 -- 75,427,209(+) T/C upstream_transcript_variant
rs1002863390 -- 75,428,807(+) A/G downstream_transcript_variant
rs1003268622 -- 75,428,756(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4463 Gene

Variant ID Type Subtype PubMed ID
esv3890880 CNV loss 25118596

Additional Variant Information for MIR4463 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4463 Gene

Disorders for MIR4463 Gene

Additional Disease Information for MIR4463

No disorders were found for MIR4463 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4463 Gene

Publications for MIR4463 Gene

  1. Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans. (PMID: 26370316) He XM … Zhou XY (Journal of atherosclerosis and thrombosis 2016) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  4. Roles of miR‑4463 in H2O2‑induced oxidative stress in human umbilical vein endothelial cells. (PMID: 28713907) Wang X … Zhou X (Molecular medicine reports 2017) 3

Products for MIR4463 Gene

Sources for MIR4463 Gene

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