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Aliases for MIR4420 Gene

Subcategory (RNA class) for MIR4420 Gene


Quality Score for this RNA gene is


Aliases for MIR4420 Gene

  • MicroRNA 4420 2 3 5
  • Hsa-Mir-4420 3
  • Mir-4420 3

External Ids for MIR4420 Gene

Previous GeneCards Identifiers for MIR4420 Gene

  • GC01U903254
  • GC01M031216

Summaries for MIR4420 Gene

Entrez Gene Summary for MIR4420 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4420 Gene

MIR4420 (MicroRNA 4420) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4420 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4420 Gene

Genomics for MIR4420 Gene

GeneHancer (GH) Regulatory Elements for MIR4420 Gene

Promoters and enhancers for MIR4420 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I030737 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 -12.0 -12036 28 HDGF PKNOX1 SMAD1 ARNT IRF4 YY1 ZNF766 CBX5 ZNF302 ZNF416 LAPTM5 LOC105378620 SNRNP40 ENSG00000229447 MATN1 MATN1-AS1 PUM1 SDC3 GC01P030755 MIR4420
GH01I030734 Enhancer 0.7 dbSUPER 0.8 +4.0 4045 2.7 BCOR MEIS2 PKNOX1 BACH1 ZMYM3 CEBPG GTF3C2 FOSL1 CTBP1 ZNF766 MATN1-AS1 MIR4420 MATN1 LAPTM5
GH01I030726 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 +9.2 9173 6.4 HDGF PKNOX1 ARNT YBX1 TCF12 POLR2B ZNF766 ARID2 FOS ATF7 MATN1-AS1 MATN1 MIR4420 LAPTM5
GH01I030733 Enhancer 0.8 ENCODE dbSUPER 0.4 +5.6 5613 0.1 GABPA ZNF395 FOSL1 ZNF766 POLR2A VEZF1 NFE2 CUX1 MAFK EMSY MIR4420 MATN1 LAPTM5
GH01I030723 Promoter/Enhancer 0.7 EPDnew dbSUPER 0.4 +15.6 15627 0.1 GC01P030723 MATN1 MATN1-AS1 MIR4420
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4420 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4420 Gene

Genomic Locations for MIR4420 Gene
77 bases
Minus strand

Genomic View for MIR4420 Gene

Genes around MIR4420 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4420 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4420 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4420 Gene

Proteins for MIR4420 Gene

Post-translational modifications for MIR4420 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4420 Gene

Domains & Families for MIR4420 Gene

Gene Families for MIR4420 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4420: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4420 Gene

Function for MIR4420 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4420 Gene

Localization for MIR4420 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4420 Gene

Pathways & Interactions for MIR4420 Gene

SuperPathways for MIR4420 Gene

No Data Available

Interacting Proteins for MIR4420 Gene

Gene Ontology (GO) - Biological Process for MIR4420 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4420 Gene

Drugs & Compounds for MIR4420 Gene

No Compound Related Data Available

Transcripts for MIR4420 Gene

mRNA/cDNA for MIR4420 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4420 Gene

No ASD Table

Relevant External Links for MIR4420 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4420 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4420 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4420 Gene:

genes like me logo Genes that share expression patterns with MIR4420: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4420 Gene

Orthologs for MIR4420 Gene

Evolution for MIR4420 Gene

Gene Tree for MIR4420 (if available)
Gene Tree for MIR4420 (if available)

No data available for Orthologs for MIR4420 Gene

Paralogs for MIR4420 Gene

No data available for Paralogs for MIR4420 Gene

Variants for MIR4420 Gene

Sequence variations from dbSNP and Humsavar for MIR4420 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002126173 -- 30,739,622(-) G/C upstream_transcript_variant
rs1002589545 -- 30,739,365(-) C/A/G upstream_transcript_variant
rs1003071303 -- 30,739,523(-) CCC/CC upstream_transcript_variant
rs1003122515 -- 30,740,611(-) G/A upstream_transcript_variant
rs1005582469 -- 30,739,159(-) T/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4420 Gene

Variant ID Type Subtype PubMed ID
dgv145n100 CNV gain 25217958
nsv460995 CNV gain 19166990
nsv509124 CNV insertion 20534489
nsv545947 CNV gain 21841781

Additional Variant Information for MIR4420 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4420 Gene

Disorders for MIR4420 Gene

Additional Disease Information for MIR4420

No disorders were found for MIR4420 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4420 Gene

Publications for MIR4420 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4420 Gene

Sources for MIR4420 Gene

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