Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4315-2 Gene

Subcategory (RNA class) for MIR4315-2 Gene


Quality Score for this RNA gene is


Aliases for MIR4315-2 Gene

  • MicroRNA 4315-2 2 3 5
  • Hsa-Mir-4315-2 3

External Ids for MIR4315-2 Gene

Previous GeneCards Identifiers for MIR4315-2 Gene

  • GC17U901507
  • GC17M043516
  • GC17M062818

Summaries for MIR4315-2 Gene

Entrez Gene Summary for MIR4315-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4315-2 Gene

MIR4315-2 (MicroRNA 4315-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4315-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4315-2 Gene

Genomics for MIR4315-2 Gene

GeneHancer (GH) Regulatory Elements for MIR4315-2 Gene

Promoters and enhancers for MIR4315-2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I064818 Enhancer 0.6 dbSUPER 0.8 +2.8 2826 2.1 GATAD2A HMG20B SAP130 NR2F1 ARID4B RARA NR2F6 SMAD4 RXRB GC17M064817 MIR4315-2 PLEKHM1P1
GH17I064823 Enhancer 0.2 dbSUPER 0.8 -2.4 -2374 2.7 RNU7-115P KPNA2P3 MIR4315-2 PLEKHM1P1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4315-2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4315-2 Gene

Genomic Locations for MIR4315-2 Gene
73 bases
Minus strand

Genomic View for MIR4315-2 Gene

Genes around MIR4315-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4315-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4315-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4315-2 Gene

Proteins for MIR4315-2 Gene

Post-translational modifications for MIR4315-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4315-2 Gene

Domains & Families for MIR4315-2 Gene

Gene Families for MIR4315-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4315-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4315-2 Gene

Function for MIR4315-2 Gene

Phenotypes From GWAS Catalog for MIR4315-2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4315-2 Gene

Localization for MIR4315-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4315-2 Gene

Pathways & Interactions for MIR4315-2 Gene

SuperPathways for MIR4315-2 Gene

No Data Available

Interacting Proteins for MIR4315-2 Gene

Gene Ontology (GO) - Biological Process for MIR4315-2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4315-2 Gene

Drugs & Compounds for MIR4315-2 Gene

No Compound Related Data Available

Transcripts for MIR4315-2 Gene

mRNA/cDNA for MIR4315-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4315-2 Gene

No ASD Table

Relevant External Links for MIR4315-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4315-2 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4315-2 Gene

Orthologs for MIR4315-2 Gene

Evolution for MIR4315-2 Gene

Gene Tree for MIR4315-2 (if available)
Gene Tree for MIR4315-2 (if available)

No data available for Orthologs for MIR4315-2 Gene

Paralogs for MIR4315-2 Gene

No data available for Paralogs for MIR4315-2 Gene

Variants for MIR4315-2 Gene

Sequence variations from dbSNP and Humsavar for MIR4315-2 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000251786 -- 64,821,676(-) G/C downstream_transcript_variant
rs1000847241 -- 64,822,782(-) C/A upstream_transcript_variant
rs1001144811 -- 64,822,528(-) TTTT/TTT upstream_transcript_variant
rs1006005582 -- 64,823,510(-) C/T upstream_transcript_variant
rs1006305229 -- 64,823,374(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4315-2 Gene

Variant ID Type Subtype PubMed ID
dgv123e55 CNV loss 17911159
dgv124e55 CNV loss 17911159
dgv1472n106 CNV deletion 24896259
dgv3274n100 CNV gain 25217958
dgv44n68 CNV loss 17160897
dgv45n68 CNV loss 17160897
esv2758691 CNV gain+loss 17122850
nsv1066765 CNV gain 25217958
nsv1070407 CNV deletion 25765185
nsv1120054 OTHER inversion 24896259
nsv1146669 OTHER inversion 26484159
nsv428342 CNV gain 18775914
nsv469875 CNV loss 16826518
nsv471504 CNV gain 19718026
nsv511056 OTHER complex 20534489

Additional Variant Information for MIR4315-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4315-2 Gene

Disorders for MIR4315-2 Gene

Additional Disease Information for MIR4315-2

No disorders were found for MIR4315-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4315-2 Gene

Publications for MIR4315-2 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4315-2 Gene

Sources for MIR4315-2 Gene

Loading form....