microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4312 Gene

Subcategory (RNA class) for MIR4312 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR4312 Gene

  • MicroRNA 4312 2 3 5
  • Hsa-Mir-4312 3
  • MIMAT0016864 51
  • MI0015842 51
  • MIR4312 2

External Ids for MIR4312 Gene

Previous GeneCards Identifiers for MIR4312 Gene

  • GC15U901218
  • GC15M069094

Summaries for MIR4312 Gene

Entrez Gene Summary for MIR4312 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4312 Gene

MIR4312 (MicroRNA 4312) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4312 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4312 Gene

Genomics for MIR4312 Gene

GeneHancer (GH) Regulatory Elements for MIR4312 Gene

Promoters and enhancers for MIR4312 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J068786 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +9.1 9129 12.4 MYC USF1 TEAD4 ZIC2 RELA RCOR1 ATF2 ZEB1 EZH2 ZNF341 ANP32A CORO2B PIAS1 MIR4312 lnc-ITGA11-4 lnc-ITGA11-6
GH15J068806 Enhancer 0.3 ENCODE 0.7 -4.8 -4752 0.2 FEZF1 ANP32A-IT1 MIR4312 ANP32A lnc-ITGA11-6
GH15J068784 Enhancer 0.4 ENCODE dbSUPER 0.4 +16.9 16928 0.2 GATA3 lnc-ITGA11-4 ANP32A MIR4312
GH15J068785 Enhancer 0.4 dbSUPER 0.4 +16.4 16449 0.7 GATA3 CTCF POLR2A lnc-ITGA11-4 ANP32A MIR4312
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4312 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4312 Gene

Genomic Locations for MIR4312 Gene
chr15:68,801,850-68,801,925
(GRCh38/hg38)
Size:
76 bases
Orientation:
Minus strand
chr15:69,094,189-69,094,264
(GRCh37/hg19)
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR4312 Gene

Genes around MIR4312 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4312 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4312 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4312 Gene

Proteins for MIR4312 Gene

Post-translational modifications for MIR4312 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4312 Gene

Domains & Families for MIR4312 Gene

Gene Families for MIR4312 Gene

HGNC:
genes like me logo Genes that share domains with MIR4312: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4312 Gene

Function for MIR4312 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4312 Gene

Localization for MIR4312 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4312 Gene

Pathways & Interactions for MIR4312 Gene

PathCards logo

SuperPathways for MIR4312 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4312 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4312 Gene

Drugs & Compounds for MIR4312 Gene

No Compound Related Data Available

Transcripts for MIR4312 Gene

mRNA/cDNA for MIR4312 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4312 Gene

No ASD Table

Relevant External Links for MIR4312 Gene

GeneLoc Exon Structure for
MIR4312

Expression for MIR4312 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4312 Gene

genes like me logo Genes that share expression patterns with MIR4312: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4312 Gene

Orthologs for MIR4312 Gene

Evolution for MIR4312 Gene

ENSEMBL:
Gene Tree for MIR4312 (if available)
TreeFam:
Gene Tree for MIR4312 (if available)

No data available for Orthologs for MIR4312 Gene

Paralogs for MIR4312 Gene

No data available for Paralogs for MIR4312 Gene

Variants for MIR4312 Gene

Additional dbSNP identifiers (rs#s) for MIR4312 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4312 Gene

Variant ID Type Subtype PubMed ID
nsv833046 CNV loss 17160897

Additional Variant Information for MIR4312 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4312

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4312 Gene

Disorders for MIR4312 Gene

Additional Disease Information for MIR4312

No disorders were found for MIR4312 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4312 Gene

Publications for MIR4312 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4312 Gene

Sources for MIR4312 Gene