microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4311 Gene

Subcategory (RNA class) for MIR4311 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR4311 Gene

  • MicroRNA 4311 2 3 5
  • Hsa-Mir-4311 3
  • MIMAT0016863 51
  • MI0015841 51
  • MIR4311 2

External Ids for MIR4311 Gene

Previous GeneCards Identifiers for MIR4311 Gene

  • GC15U901241
  • GC15P066332
  • GC15P066049
  • GC15P066304
  • GC15P069501
  • GC15P069609
  • GC15P069664
  • GC15P066301
  • GC15P066341
  • GC15P066870
  • GC15P067398
  • GC15P067923
  • GC15P068413
  • GC15P068918
  • GC15P069392

Summaries for MIR4311 Gene

Entrez Gene Summary for MIR4311 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4311 Gene

MIR4311 (MicroRNA 4311) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4311 include Anthracosis.

Additional gene information for MIR4311 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4311 Gene

Genomics for MIR4311 Gene

GeneHancer (GH) Regulatory Elements for MIR4311 Gene

Promoters and enhancers for MIR4311 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J066038 Enhancer 0.8 Ensembl ENCODE 500.7 -1.0 -1032 2.4 ZSCAN5C RBM25 NFIC ZBTB17 BCOR SIX4 ZBTB48 RCOR1 SCRT1 ADNP MIR4311 IGDCC4 lnc-DENND4A-6 MEGF11
GH15J066042 Enhancer 0.9 Ensembl ENCODE 0.7 +2.0 2012 3.3 USF1 TEAD4 TCF7 ATF2 FOXA2 YY1 FOXA1 ZNF335 MYC ZNF189 IGDCC4 MIR4311 RF00017-1821 MEGF11
GH15J066067 Enhancer 0.8 Ensembl ENCODE 0.3 +26.9 26868 3.8 USF1 TEAD4 HDAC2 RBM25 NANOG TCF12 SIN3A FEZF1 KAT2B SMARCA4 MIR4311 RF00017-1821 MEGF11
GH15J066080 Enhancer 0.8 Ensembl ENCODE 0.3 +40.7 40747 1.6 FOS CTCF FOXA2 NFIC FOSL2 YY1 HNF4A RAD21 KDM1A BHLHE40 MIR4311 RF00017-1821 MEGF11
GH15J066095 Enhancer 0.8 Ensembl CraniofacialAtlas 0.2 +56.1 56068 1.4 NCOR1 ZIC2 ZNF341 FOXA2 TFDP1 SAP130 POLR2A SMAD4 ZNF189 RARA MIR4311 RF00017-1821 MEGF11
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4311 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4311 Gene

Genomic Locations for MIR4311 Gene
chr15:66,040,233-66,040,332
(GRCh38/hg38)
Size:
100 bases
Orientation:
Plus strand
chr15:66,332,571-66,332,670
(GRCh37/hg19)
Size:
100 bases
Orientation:
Plus strand

Genomic View for MIR4311 Gene

Genes around MIR4311 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4311 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4311 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4311 Gene

Proteins for MIR4311 Gene

Post-translational modifications for MIR4311 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4311 Gene

Domains & Families for MIR4311 Gene

Gene Families for MIR4311 Gene

HGNC:
genes like me logo Genes that share domains with MIR4311: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4311 Gene

Function for MIR4311 Gene

Phenotypes From GWAS Catalog for MIR4311 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4311 Gene

Localization for MIR4311 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4311 Gene

Pathways & Interactions for MIR4311 Gene

PathCards logo

SuperPathways for MIR4311 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4311 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4311 Gene

Drugs & Compounds for MIR4311 Gene

No Compound Related Data Available

Transcripts for MIR4311 Gene

mRNA/cDNA for MIR4311 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4311 Gene

No ASD Table

Relevant External Links for MIR4311 Gene

GeneLoc Exon Structure for
MIR4311

Expression for MIR4311 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4311 Gene

genes like me logo Genes that share expression patterns with MIR4311: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4311 Gene

Orthologs for MIR4311 Gene

Evolution for MIR4311 Gene

ENSEMBL:
Gene Tree for MIR4311 (if available)
TreeFam:
Gene Tree for MIR4311 (if available)

No data available for Orthologs for MIR4311 Gene

Paralogs for MIR4311 Gene

No data available for Paralogs for MIR4311 Gene

Variants for MIR4311 Gene

Additional dbSNP identifiers (rs#s) for MIR4311 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4311 Gene

Variant ID Type Subtype PubMed ID
esv2760035 CNV loss 17122850
nsv1047176 CNV gain 25217958
nsv1572 CNV deletion 18451855
nsv509572 CNV insertion 20534489

Additional Variant Information for MIR4311 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4311

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4311 Gene

Disorders for MIR4311 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR4311 Gene - From: DISEASES

Disorder Aliases PubMed IDs
anthracosis
  • pneumoconiosis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR4311

genes like me logo Genes that share disorders with MIR4311: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4311 Gene

Publications for MIR4311 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4311 Gene

Sources for MIR4311 Gene