microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4305 Gene

Subcategory (RNA class) for MIR4305 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR4305 Gene

  • MicroRNA 4305 2 3 5
  • Hsa-Mir-4305 2 3
  • MIR4305 2 5
  • MIMAT0016857 50
  • MI0015835 50

External Ids for MIR4305 Gene

Previous GeneCards Identifiers for MIR4305 Gene

  • GC13U900759
  • GC13M040238

Summaries for MIR4305 Gene

Entrez Gene Summary for MIR4305 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4305 Gene

MIR4305 (MicroRNA 4305) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4305 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4305 Gene

Genomics for MIR4305 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4305 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J039655 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +8.1 8134 2 HNRNPL GATAD2A PRDM10 TFE3 ZNF692 POLR2A BACH1 ZNF143 PRDM1 ZIC2 COG6 HSALNG0096503 MIR4305
GH13J039688 Enhancer 0.5 Ensembl 0.4 -25.0 -24965 0.2 IKZF2 RUNX3 FOSL1 NBN TBX21 ATF7 MTA2 BHLHE40 ZNF217 MIR4305 COG6 piR-61101-149 FOXO1
GH13J039659 Enhancer 0.3 Ensembl 0.7 +4.7 4734 0.4 MZF1 COG6 HSALNG0096503 MIR4305
GH13J039684 Enhancer 0.5 Ensembl 0.4 -20.7 -20662 0.4 CTCF PRDM1 RAD21 ARID3A SMC3 ZNF654 ZBTB33 NFRKB MIR4305 COG6 piR-61101-149 FOXO1
GH13J039685 Enhancer 0.5 Ensembl 0.4 -21.7 -21666 1.2 IKZF2 RUNX3 CTCF SPI1 MTA2 SREBF1 IKZF1 COG6 MIR4305 piR-61101-149 FOXO1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4305 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4305 Gene

Genomic Locations for MIR4305 Gene
chr13:39,664,034-39,664,135
(GRCh38/hg38)
Size:
102 bases
Orientation:
Minus strand
chr13:40,238,171-40,238,272
(GRCh37/hg19)
Size:
102 bases
Orientation:
Minus strand

Genomic View for MIR4305 Gene

Genes around MIR4305 on UCSC Golden Path with GeneCards custom track
MIR4305 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4305 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4305 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4305 Gene

Proteins for MIR4305 Gene

Post-translational modifications for MIR4305 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4305 Gene

Domains & Families for MIR4305 Gene

Gene Families for MIR4305 Gene

HGNC:
genes like me logo Genes that share domains with MIR4305: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4305 Gene

Function for MIR4305 Gene

Phenotypes From GWAS Catalog for MIR4305 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4305 Gene

Localization for MIR4305 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4305 Gene

Pathways & Interactions for MIR4305 Gene

PathCards logo

SuperPathways for MIR4305 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4305 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4305 Gene

Drugs & Compounds for MIR4305 Gene

No Compound Related Data Available

Transcripts for MIR4305 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4305 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AD73_9606 precursor_RNA 102 4

HGNC: 38301,

RefSeq: NR_036190,

Ensembl: ENST00000583252 (view in UCSC) ,

miRBase: MI0015835,

URS000075AA82_9606 miRNA 18 2

RefSeq: NR_036190,

miRBase: MIMAT0016857,

MIR4305 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4305 Gene

No ASD Table

Relevant External Links for MIR4305 Gene

GeneLoc Exon Structure for
MIR4305

No data available for mRNA/cDNA for MIR4305 Gene

Expression for MIR4305 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4305 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4305

genes like me logo Genes that share expression patterns with MIR4305: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4305 Gene

Orthologs for MIR4305 Gene

Evolution for MIR4305 Gene

ENSEMBL:
Gene Tree for MIR4305 (if available)
TreeFam:
Gene Tree for MIR4305 (if available)

No data available for Orthologs for MIR4305 Gene

Paralogs for MIR4305 Gene

No data available for Paralogs for MIR4305 Gene

Variants for MIR4305 Gene

Additional dbSNP identifiers (rs#s) for MIR4305 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4305 Gene

Variant ID Type Subtype PubMed ID
esv33028 CNV gain 17666407
esv3631837 CNV gain 21293372
nsv1054600 CNV gain 25217958
nsv832586 CNV gain+loss 17160897

Additional Variant Information for MIR4305 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4305

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4305 Gene

Disorders for MIR4305 Gene

Additional Disease Information for MIR4305

No disorders were found for MIR4305 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4305 Gene

Publications for MIR4305 Gene

  1. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. (PMID: 25231870) Perry JR … Ong KK (Nature 2014) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4305 Gene

Sources for MIR4305 Gene