microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4304 Gene

Subcategory (RNA class) for MIR4304 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR4304 Gene

  • MicroRNA 4304 2 3 5
  • Hsa-Mir-4304 2 3
  • MIR4304 2 5
  • MIMAT0016854 50
  • MI0015832 50

External Ids for MIR4304 Gene

Previous GeneCards Identifiers for MIR4304 Gene

  • GC12U901385
  • GC12M123495

Summaries for MIR4304 Gene

Entrez Gene Summary for MIR4304 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4304 Gene

MIR4304 (MicroRNA 4304) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4304 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4304 Gene

Genomics for MIR4304 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4304 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J123007 Enhancer 0.4 Ensembl 0.7 +3.5 3527 0.4 ZNF600 ZNF316 BHLHE40 MAFK PITPNM2 CDK2AP1 MIR4304 piR-35674-117 ABCB9 L13304-010
GH12J123008 Enhancer 0.3 Ensembl 0.7 +3.0 3027 0.2 ZNF335 GLIS1 PITPNM2 MIR4304 piR-35674-117 ABCB9 L13304-010
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4304 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4304 Gene

Genomic Locations for MIR4304 Gene
chr12:123,010,667-123,010,728
(GRCh38/hg38)
Size:
62 bases
Orientation:
Minus strand
chr12:123,495,214-123,495,275
(GRCh37/hg19)
Size:
62 bases
Orientation:
Minus strand

Genomic View for MIR4304 Gene

Genes around MIR4304 on UCSC Golden Path with GeneCards custom track
MIR4304 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4304 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4304 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4304 Gene

Proteins for MIR4304 Gene

Post-translational modifications for MIR4304 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4304 Gene

Domains & Families for MIR4304 Gene

Gene Families for MIR4304 Gene

HGNC:
genes like me logo Genes that share domains with MIR4304: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4304 Gene

Function for MIR4304 Gene

Phenotypes From GWAS Catalog for MIR4304 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4304 Gene

Localization for MIR4304 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4304 Gene

Pathways & Interactions for MIR4304 Gene

PathCards logo

SuperPathways for MIR4304 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4304 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4304 Gene

Drugs & Compounds for MIR4304 Gene

No Compound Related Data Available

Transcripts for MIR4304 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4304 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A30A_9606 precursor_RNA 62 4

HGNC: 38276,

RefSeq: NR_036187,

Ensembl: ENST00000580964 (view in UCSC) ,

miRBase: MI0015832,

URS000075E8E8_9606 miRNA 17 2

RefSeq: NR_036187,

miRBase: MIMAT0016854,

MIR4304 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4304 Gene

No ASD Table

Relevant External Links for MIR4304 Gene

GeneLoc Exon Structure for
MIR4304

No data available for mRNA/cDNA for MIR4304 Gene

Expression for MIR4304 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4304

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4304 Gene

Orthologs for MIR4304 Gene

Evolution for MIR4304 Gene

ENSEMBL:
Gene Tree for MIR4304 (if available)
TreeFam:
Gene Tree for MIR4304 (if available)

No data available for Orthologs for MIR4304 Gene

Paralogs for MIR4304 Gene

No data available for Paralogs for MIR4304 Gene

Variants for MIR4304 Gene

Additional dbSNP identifiers (rs#s) for MIR4304 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4304 Gene

Variant ID Type Subtype PubMed ID
dgv22n68 CNV loss 17160897
nsv455732 CNV loss 19166990
nsv517200 CNV loss 19592680
nsv560492 CNV loss 21841781
nsv560494 CNV loss 21841781

Additional Variant Information for MIR4304 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4304

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4304 Gene

Disorders for MIR4304 Gene

Additional Disease Information for MIR4304

No disorders were found for MIR4304 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4304 Gene

Publications for MIR4304 Gene

  1. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S … Sullivan PF (Nature genetics 2013) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4304 Gene

Sources for MIR4304 Gene