MIR4302 Gene (RNA Gene)

MicroRNA 4302

GC12M025874
GIFtS:
9
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4302 Gene

Subcategory (RNA class) for MIR4302 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR4302 Gene

  • MicroRNA 4302 2 3 5
  • Hsa-Mir-4302 2 3
  • MIR4302 2 5
  • MIMAT0016855 50
  • MI0015833 50

External Ids for MIR4302 Gene

Previous GeneCards Identifiers for MIR4302 Gene

  • GC12U901420
  • GC12M026026

Summaries for MIR4302 Gene

Entrez Gene Summary for MIR4302 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4302 Gene

MIR4302 (MicroRNA 4302) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4302 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4302 Gene

Genomics for MIR4302 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for MIR4302 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH12J025875 Enhancer 0.5 Ensembl ENCODE 600.7 -1.5 -1515 0.8 ZNF512 CEBPB MIR4302 RASSF8 RASSF8-AS1 ENSG00000256256 LMNTD1
GH12J025867 Enhancer 0.6 Ensembl ENCODE 0.4 +7.1 7078 1.6 OSR2 WT1 MZF1 MIR4302 lnc-RASSF8-3 RASSF8 LMNTD1
GH12J025864 Enhancer 0.6 Ensembl 0.4 +9.8 9778 0.2 ZBTB44 ZSCAN5C OSR2 WT1 HIC1 FEZF1 PRDM6 KLF10 INSM2 SP7 lnc-RASSF8-3 MIR4302 RASSF8 LMNTD1
GH12J025863 Enhancer 0.6 ENCODE 0.4 +10.7 10716 0.2 JUND ZEB1 CEBPB FOS ZFP69B HIC1 PRDM6 CBX8 SP7 ZEB2 lnc-RASSF8-3 MIR4302 RASSF8 LMNTD1
GH12J025876 Enhancer 0.2 ENCODE 0.7 -2.4 -2400 0.2 RASSF8 RASSF8-AS1 MIR4302 ENSG00000256256 LMNTD1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4302 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4302 Gene

Genomic Locations for MIR4302 Gene
chr12:25,874,020-25,874,079
(GRCh38/hg38)
Size:
60 bases
Orientation:
Minus strand
chr12:26,026,953-26,027,012
(GRCh37/hg19)
Size:
60 bases
Orientation:
Minus strand

Genomic View for MIR4302 Gene

Genes around MIR4302 on UCSC Golden Path with GeneCards custom track
MIR4302 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4302 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4302 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4302 Gene

Proteins for MIR4302 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4302 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4302 Gene

Domains & Families for MIR4302 Gene

Gene Families for MIR4302 Gene

HGNC:
genes like me logo Genes that share domains with MIR4302: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4302 Gene

Function for MIR4302 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for MIR4302 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4302 Gene

Localization for MIR4302 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4302 Gene

Pathways & Interactions for MIR4302 Gene

PathCards logo

SuperPathways for MIR4302 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4302 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4302 Gene

Drugs & Compounds for MIR4302 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4302 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4302 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C647_9606 precursor_RNA 60 4

HGNC: 38185,

RefSeq: NR_036188,

Ensembl: ENST00000638058 (view in UCSC) ,

miRBase: MI0015833,

URS000075E65D_9606 miRNA 18 2

RefSeq: NR_036188,

miRBase: MIMAT0016855,

MIR4302 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4302 Gene

No ASD Table

Relevant External Links for MIR4302 Gene

GeneLoc Exon Structure for
MIR4302

No data available for mRNA/cDNA for MIR4302 Gene

Expression for MIR4302 Gene

Products:

  1. Primer
  2. Gene Expression Assay

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4302

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4302 Gene

Orthologs for MIR4302 Gene

Evolution for MIR4302 Gene

ENSEMBL:
Gene Tree for MIR4302 (if available)
TreeFam:
Gene Tree for MIR4302 (if available)

No data available for Orthologs for MIR4302 Gene

Paralogs for MIR4302 Gene

No data available for Paralogs for MIR4302 Gene

Variants for MIR4302 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for MIR4302 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4302 Gene

Variant ID Type Subtype PubMed ID
esv2759886 CNV loss 17122850
nsv1035319 CNV loss 25217958

Additional Variant Information for MIR4302 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4302

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4302 Gene

Disorders for MIR4302 Gene

Additional Disease Information for MIR4302

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4302 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4302 Gene

Publications for MIR4302 Gene

  1. Circular RNA hsa_circRNA_103809 promotes lung cancer progression via facilitating ZNF121-dependent MYC expression by sequestering miR-4302. (PMID: 29698681) Liu W … Sun S (Biochemical and biophysical research communications 2018) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

ExternalLinks

View latest publications for MIR4302 gene in Mastermind

Products for MIR4302 Gene

Sources for MIR4302 Gene