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Aliases for MIR4301 Gene

Subcategory (RNA class) for MIR4301 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4301 Gene

  • MicroRNA 4301 2 3 5
  • Hsa-Mir-4301 3

External Ids for MIR4301 Gene

Previous GeneCards Identifiers for MIR4301 Gene

  • GC11U901717
  • GC11M113320

Summaries for MIR4301 Gene

Entrez Gene Summary for MIR4301 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4301 Gene

MIR4301 (MicroRNA 4301) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4301 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4301 Gene

Genomics for MIR4301 Gene

GeneHancer (GH) Regulatory Elements for MIR4301 Gene

Promoters and enhancers for MIR4301 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I113445 Enhancer 0.7 ENCODE 0.8 +2.8 2763 3.2 ATF1 ZBTB21 INSM2 BATF IRF4 FOSL1 CTBP1 PRDM10 FOS ZNF600 DRD2 MIR4301 GC11M113417 GC11M113416
GH11I113475 Promoter 0.9 EPDnew 0.3 -25.3 -25330 0.1 SP3 SP2 REST GLIS2 ZFHX2 GLIS1 ZBTB17 EZH2 DRD2 MIR4301
GH11I113467 Promoter 0.6 EPDnew 0.4 -17.5 -17472 0.1 MNT DRD2 MIR4301
GH11I113474 Enhancer 0.8 ENCODE 0.3 -24.4 -24426 0.2 ELF3 RB1 KLF17 SIN3A ZSCAN9 ZBTB40 CHAMP1 ZNF335 ZNF766 GLIS2 DRD2 MIR4301
GH11I113457 Enhancer 0.5 ENCODE 0.4 -7.8 -7806 0.2 POLR2A GLIS1 ZNF341 ZIC2 ENSG00000256757 TTC12 LOC105369499 DRD2 MIR4301
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4301 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4301 Gene

Genomic Locations for MIR4301 Gene
chr11:113,450,023-113,450,088
(GRCh38/hg38)
Size:
66 bases
Orientation:
Minus strand
chr11:113,320,745-113,320,810
(GRCh37/hg19)

Genomic View for MIR4301 Gene

Genes around MIR4301 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4301 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4301 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4301 Gene

Proteins for MIR4301 Gene

Post-translational modifications for MIR4301 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4301 Gene

Domains & Families for MIR4301 Gene

Gene Families for MIR4301 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4301: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4301 Gene

Function for MIR4301 Gene

Phenotypes From GWAS Catalog for MIR4301 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4301 Gene

Localization for MIR4301 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4301 Gene

Pathways & Interactions for MIR4301 Gene

SuperPathways for MIR4301 Gene

No Data Available

Interacting Proteins for MIR4301 Gene

Gene Ontology (GO) - Biological Process for MIR4301 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4301 Gene

Drugs & Compounds for MIR4301 Gene

No Compound Related Data Available

Transcripts for MIR4301 Gene

mRNA/cDNA for MIR4301 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4301 Gene

No ASD Table

Relevant External Links for MIR4301 Gene

GeneLoc Exon Structure for
MIR4301
ECgene alternative splicing isoforms for
MIR4301

Expression for MIR4301 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4301 Gene:

MIR4301
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4301 Gene

Orthologs for MIR4301 Gene

Evolution for MIR4301 Gene

ENSEMBL:
Gene Tree for MIR4301 (if available)
TreeFam:
Gene Tree for MIR4301 (if available)

No data available for Orthologs for MIR4301 Gene

Paralogs for MIR4301 Gene

No data available for Paralogs for MIR4301 Gene

Variants for MIR4301 Gene

Sequence variations from dbSNP and Humsavar for MIR4301 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000319532 -- 113,450,531(-) C/A upstream_transcript_variant
rs1004283455 -- 113,451,714(-) T/C upstream_transcript_variant
rs1006790653 -- 113,449,533(-) G/T downstream_transcript_variant
rs1006974167 -- 113,452,062(-) C/G upstream_transcript_variant
rs1008423999 -- 113,450,984(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4301 Gene

Variant ID Type Subtype PubMed ID
nsv556444 CNV gain 21841781

Additional Variant Information for MIR4301 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4301

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4301 Gene

Disorders for MIR4301 Gene

Additional Disease Information for MIR4301

No disorders were found for MIR4301 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4301 Gene

Publications for MIR4301 Gene

  1. Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. (PMID: 24058526) Bhatnagar P … Arking DE (PloS one 2013) 3 58
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4301 Gene

Sources for MIR4301 Gene

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