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Aliases for MIR4300 Gene

Subcategory (RNA class) for MIR4300 Gene


Quality Score for this RNA gene is


Aliases for MIR4300 Gene

  • MicroRNA 4300 2 3 5
  • Hsa-Mir-4300 3

External Ids for MIR4300 Gene

Previous GeneCards Identifiers for MIR4300 Gene

  • GC11U901675
  • GC11M081601

Summaries for MIR4300 Gene

Entrez Gene Summary for MIR4300 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4300 Gene

MIR4300 (MicroRNA 4300) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4300 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4300 Gene

Genomics for MIR4300 Gene

GeneHancer (GH) Regulatory Elements for MIR4300 Gene

Promoters and enhancers for MIR4300 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I081868 Enhancer 0.9 Ensembl ENCODE 0.3 +20.6 20646 2.4 SMAD1 MAX EBF1 BMI1 RELA POLR2A NFATC1 ZNF207 ATF7 ETV6 MIR4300 ENSG00000270701 GC11M081628
GH11I081874 Enhancer 0.4 ENCODE 0.4 +16.0 15982 0.2 PKNOX1 POLR2A MIR4300 ENSG00000270701 GC11M081628
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4300 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4300 Gene

Genomic Locations for MIR4300 Gene
96 bases
Minus strand

Genomic View for MIR4300 Gene

Genes around MIR4300 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4300 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4300 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4300 Gene

ORGUL Member Location for MIR4300 Gene

ORGUL Member Location for MIR4300 gene

Proteins for MIR4300 Gene

Post-translational modifications for MIR4300 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4300 Gene

Domains & Families for MIR4300 Gene

Gene Families for MIR4300 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4300: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4300 Gene

Function for MIR4300 Gene

Phenotypes From GWAS Catalog for MIR4300 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4300 Gene

Localization for MIR4300 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4300 Gene

Pathways & Interactions for MIR4300 Gene

SuperPathways for MIR4300 Gene

No Data Available

Interacting Proteins for MIR4300 Gene

Gene Ontology (GO) - Biological Process for MIR4300 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4300 Gene

Drugs & Compounds for MIR4300 Gene

No Compound Related Data Available

Transcripts for MIR4300 Gene

mRNA/cDNA for MIR4300 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4300 Gene

No ASD Table

Relevant External Links for MIR4300 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4300 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4300 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4300 Gene:

genes like me logo Genes that share expression patterns with MIR4300: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4300 Gene

Orthologs for MIR4300 Gene

Evolution for MIR4300 Gene

Gene Tree for MIR4300 (if available)
Gene Tree for MIR4300 (if available)

No data available for Orthologs for MIR4300 Gene

Paralogs for MIR4300 Gene

No data available for Paralogs for MIR4300 Gene

Variants for MIR4300 Gene

Sequence variations from dbSNP and Humsavar for MIR4300 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000111274 -- 81,890,450(-) A/G downstream_transcript_variant
rs1000163767 -- 81,890,674(-) G/A downstream_transcript_variant
rs1001786528 -- 81,891,657(-) T/C upstream_transcript_variant
rs1001914067 -- 81,892,415(-) C/T upstream_transcript_variant
rs1003588657 -- 81,891,029(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4300 Gene

Variant ID Type Subtype PubMed ID
dgv53e55 CNV loss 17911159
esv2664646 CNV deletion 23128226
esv2759843 CNV loss 17122850
esv3579768 CNV loss 25503493
esv3626971 CNV loss 21293372
esv3626972 CNV loss 21293372
nsv1037497 CNV gain 25217958
nsv1048620 CNV gain 25217958
nsv1054416 CNV gain 25217958
nsv437132 CNV loss 16327808
nsv468759 CNV gain 19166990
nsv555488 CNV loss 21841781
nsv555553 CNV gain 21841781
nsv555558 CNV gain 21841781

Additional Variant Information for MIR4300 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4300 Gene

Disorders for MIR4300 Gene

Additional Disease Information for MIR4300

No disorders were found for MIR4300 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4300 Gene

Publications for MIR4300 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis. (PMID: 29016859) Ogura Y … Japan Scoliosis Clinical Research Group (Human molecular genetics 2017) 3

Products for MIR4300 Gene

Sources for MIR4300 Gene

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