microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4291 Gene

Subcategory (RNA class) for MIR4291 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR4291 Gene

  • MicroRNA 4291 2 3 5
  • Hsa-Mir-4291 2 3
  • MIR4291 2 5
  • MIMAT0016922 50
  • MI0015900 50

External Ids for MIR4291 Gene

Previous GeneCards Identifiers for MIR4291 Gene

  • GC09U901625
  • GC09P096581

Summaries for MIR4291 Gene

Entrez Gene Summary for MIR4291 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4291 Gene

MIR4291 (MicroRNA 4291) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4291 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4291 Gene

Genomics for MIR4291 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4291 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J093826 Enhancer 0.8 ENCODE CraniofacialAtlas 0.4 +8.0 7962 2 HNRNPL CTCF KDM1A PKNOX1 ZNF24 EZH2 YY1 EGR1 ZNF444 USF1 FGD3 MIR4291 ENSG00000231990 LOC101928014 BARX1 PHF2
GH09J093813 Enhancer 0.5 Ensembl 0.7 -4.6 -4604 1.3 CTCF POLR2A GTF2F1 FOXA2 SPI1 SIN3A SMARCA4 RAD21 MIR4291 ENSG00000231990 BARX1 PHF2
GH09J093810 Enhancer 0.6 Ensembl CraniofacialAtlas 0.4 -9.0 -8997 0.9 ZBTB33 EGR1 NFIC MEIS2 ENSG00000231990 MIR4291 BARX1 PHF2
GH09J093811 Enhancer 0.3 Ensembl 0.4 -8.3 -8256 0.2 ZBTB33 ENSG00000231990 MIR4291 BARX1 PHF2
GH09J093829 Enhancer 0.3 CraniofacialAtlas 0.4 +10.5 10462 1 ZNF7 MIR4291 ENSG00000231990 LOC101928014 BARX1 PHF2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4291 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4291 Gene

Genomic Locations for MIR4291 Gene
chr9:93,819,357-93,819,421
(GRCh38/hg38)
Size:
65 bases
Orientation:
Plus strand
chr9:96,581,639-96,581,703
(GRCh37/hg19)
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR4291 Gene

Genes around MIR4291 on UCSC Golden Path with GeneCards custom track
MIR4291 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4291 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4291 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4291 Gene

Proteins for MIR4291 Gene

Post-translational modifications for MIR4291 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4291 Gene

Domains & Families for MIR4291 Gene

Gene Families for MIR4291 Gene

HGNC:
genes like me logo Genes that share domains with MIR4291: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4291 Gene

Function for MIR4291 Gene

Phenotypes From GWAS Catalog for MIR4291 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4291 Gene

Localization for MIR4291 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4291 Gene

Pathways & Interactions for MIR4291 Gene

PathCards logo

SuperPathways for MIR4291 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4291 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4291 Gene

Drugs & Compounds for MIR4291 Gene

No Compound Related Data Available

Transcripts for MIR4291 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4291 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075998A_9606 precursor_RNA 65 4

HGNC: 38267,

RefSeq: NR_036254,

Ensembl: ENST00000584984 (view in UCSC) ,

miRBase: MI0015900,

URS00002FB584_9606 miRNA 16 2

RefSeq: NR_036254,

miRBase: MIMAT0016922,

MIR4291 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4291 Gene

No ASD Table

Relevant External Links for MIR4291 Gene

GeneLoc Exon Structure for
MIR4291

No data available for mRNA/cDNA for MIR4291 Gene

Expression for MIR4291 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4291 Gene

Orthologs for MIR4291 Gene

Evolution for MIR4291 Gene

ENSEMBL:
Gene Tree for MIR4291 (if available)
TreeFam:
Gene Tree for MIR4291 (if available)

No data available for Orthologs for MIR4291 Gene

Paralogs for MIR4291 Gene

No data available for Paralogs for MIR4291 Gene

Variants for MIR4291 Gene

Additional dbSNP identifiers (rs#s) for MIR4291 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4291 Gene

Variant ID Type Subtype PubMed ID
nsv6619 CNV insertion 18451855

Additional Variant Information for MIR4291 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4291

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4291 Gene

Disorders for MIR4291 Gene

No disorders were found for MIR4291 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4291 Gene

Publications for MIR4291 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4291 Gene

Sources for MIR4291 Gene