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Aliases for MIR4290 Gene

Subcategory (RNA class) for MIR4290 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR4290 Gene

  • MicroRNA 4290 2 3 5
  • Hsa-Mir-4290 3

External Ids for MIR4290 Gene

Previous GeneCards Identifiers for MIR4290 Gene

  • GC09U901557
  • GC09M092785

Summaries for MIR4290 Gene

Entrez Gene Summary for MIR4290 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4290 Gene

MIR4290 (MicroRNA 4290) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4290 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4290 Gene

Genomics for MIR4290 Gene

GeneHancer (GH) Regulatory Elements for MIR4290 Gene

Promoters and enhancers for MIR4290 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J090024 Enhancer 0.4 Ensembl 650.7 -1.3 -1266 0.4 IKZF1 IKZF2 SPI1 MIR4290 MIR4290HG
GH09J089998 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +22.1 22116 5.3 FOXA2 MLX ARID4B DMAP1 ZNF48 RAD21 RARA YY1 ZNF335 EGR1 MIR4290 GC09M089956
GH09J089992 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.5 29459 4.1 FOXA2 MLX ZFP64 ARID4B SIN3A YBX1 GLI4 ZNF48 ETS1 YY1 GADD45G GC09M089956 MIR4290
GH09J090019 Enhancer 0.5 ENCODE dbSUPER 0.7 +3.4 3354 1.9 MNT MIR4290 MIR4290HG GC09M089956
GH09J089983 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.3 +39.2 39230 1.1 POLR2A CBFB JUNB CREB1 FOSL2 FOS RUNX3 GC09M089956 LOC101927847 MIR4290
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4290 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4290 Gene

Genomic Locations for MIR4290 Gene
chr9:90,023,441-90,023,535
(GRCh38/hg38)
Size:
95 bases
Orientation:
Minus strand
chr9:92,785,723-92,785,817
(GRCh37/hg19)

Genomic View for MIR4290 Gene

Genes around MIR4290 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4290 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4290 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4290 Gene

Proteins for MIR4290 Gene

Post-translational modifications for MIR4290 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4290 Gene

Domains & Families for MIR4290 Gene

Gene Families for MIR4290 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4290: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4290 Gene

Function for MIR4290 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4290 Gene

Localization for MIR4290 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4290 Gene

Pathways & Interactions for MIR4290 Gene

SuperPathways for MIR4290 Gene

No Data Available

Interacting Proteins for MIR4290 Gene

Gene Ontology (GO) - Biological Process for MIR4290 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4290 Gene

Drugs & Compounds for MIR4290 Gene

No Compound Related Data Available

Transcripts for MIR4290 Gene

mRNA/cDNA for MIR4290 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4290 Gene

No ASD Table

Relevant External Links for MIR4290 Gene

GeneLoc Exon Structure for
MIR4290
ECgene alternative splicing isoforms for
MIR4290

Expression for MIR4290 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4290 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4290 Gene:

MIR4290
genes like me logo Genes that share expression patterns with MIR4290: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4290 Gene

Orthologs for MIR4290 Gene

Evolution for MIR4290 Gene

ENSEMBL:
Gene Tree for MIR4290 (if available)
TreeFam:
Gene Tree for MIR4290 (if available)

No data available for Orthologs for MIR4290 Gene

Paralogs for MIR4290 Gene

No data available for Paralogs for MIR4290 Gene

Variants for MIR4290 Gene

Sequence variations from dbSNP and Humsavar for MIR4290 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000246936 -- 90,024,979(-) CA/ upstream_transcript_variant
rs1000833976 -- 90,023,898(-) G/A upstream_transcript_variant
rs1000884594 -- 90,025,530(-) G/T upstream_transcript_variant
rs1001371468 -- 90,024,107(-) A/G upstream_transcript_variant
rs1001742089 -- 90,024,422(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4290 Gene

Variant ID Type Subtype PubMed ID
esv3621038 CNV gain 21293372

Additional Variant Information for MIR4290 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4290

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4290 Gene

Disorders for MIR4290 Gene

Additional Disease Information for MIR4290

No disorders were found for MIR4290 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4290 Gene

Publications for MIR4290 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4290 Gene

Sources for MIR4290 Gene

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