microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4279 Gene

Data sources for MIR4279 Gene:

RNA type for MIR4279 Gene

miRNA

Aliases for MIR4279 Gene

External Ids for MIR4279 Gene

Previous GeneCards Identifiers for MIR4279 Gene

  • GC05U901409

Summaries for MIR4279 Gene

Entrez Gene Summary for MIR4279 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4279 Gene

MIR4279 (MicroRNA 4279) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4279 include Asymptomatic Dengue.

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4279 Gene

Genomics for MIR4279 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4279 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J031935 Promoter/Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -0.7 -699 2.7 CEBPB KLF9 MZF1 ZBTB17 ZNF558 PRDM10 EP300 MIR4279 PDZD2 piR-32214-537 GOLPH3
GH05J031939 Enhancer 0.7 Ensembl ENCODE dbSUPER 0.7 -3.2 -3242 0.8 CEBPA CEBPB HNF4A PDZD2 MIR4279 piR-32214-537 GOLPH3
GH05J031931 Enhancer 0.6 Ensembl ENCODE 0.7 +3.8 3833 1 ZNF217 ELF1 SMARCE1 FOXA1 DPF2 PDZD2 MIR4279 ENSG00000249774 GOLPH3
GH05J031933 Enhancer 0.6 Ensembl ENCODE 0.7 +2.2 2244 1.4 ZNF146 CTCF EP300 EZH2 PDZD2 MIR4279 ENSG00000249774 GOLPH3
GH05J031928 Enhancer 0.7 Ensembl dbSUPER 0.4 +7.0 6958 0.4 ZNF654 CTCF KLF9 RAD21 SMC3 TEAD3 ZNF24 ZNF143 TRIM22 PDZD2 ENSG00000249774 MIR4279 GOLPH3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4279 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4279 Gene

Latest Assembly
chr5:31,936,102-31,936,159
(GRCh38/hg38)
Size:
58 bases
Orientation:
Minus strand

Previous Assembly
chr5:31,936,208-31,936,265
(GRCh37/hg19 by Entrez Gene)
Size:
58 bases
Orientation:
Minus strand

chr5:31,936,208-31,936,265
(GRCh37/hg19 by Ensembl)
Size:
58 bases
Orientation:
Minus strand

Genomic View for MIR4279 Gene

Genes around MIR4279 on UCSC Golden Path with GeneCards custom track
MIR4279 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4279 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4279 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4279 Gene

Proteins for MIR4279 Gene

Post-translational modifications for MIR4279 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4279 Gene

Domains & Families for MIR4279 Gene

Gene Families for MIR4279 Gene

HGNC:
genes like me logo Genes that share domains with MIR4279: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4279 Gene

Function for MIR4279 Gene

Phenotypes From GWAS Catalog for MIR4279 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4279 Gene

Localization for MIR4279 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR4279 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4279 Gene

Pathways & Interactions for MIR4279 Gene

PathCards logo

SuperPathways for MIR4279 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4279 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4279 Gene

Drugs & Compounds for MIR4279 Gene

No Compound Related Data Available

Transcripts for MIR4279 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4279 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075B6EF_9606 precursor_RNA 58 3

RefSeq: NR_036241,

Ensembl: ENST00000582091 (view in UCSC) ,

miRBase: MI0015887,

URS000075D139_9606 miRNA 16 3

RefSeq: NR_036241,

miRBase: MIMAT0016909,

TarBase: hsa-miR-4279,

MIR4279 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4279 Gene

No ASD Table

Relevant External Links for MIR4279 Gene

GeneLoc Exon Structure for
MIR4279

No data available for mRNA/cDNA for MIR4279 Gene

Expression for MIR4279 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4279

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4279 Gene

Orthologs for MIR4279 Gene

Evolution for MIR4279 Gene

ENSEMBL:
Gene Tree for MIR4279 (if available)
TreeFam:
Gene Tree for MIR4279 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4279

No data available for Orthologs for MIR4279 Gene

Paralogs for MIR4279 Gene

No data available for Paralogs for MIR4279 Gene

Variants for MIR4279 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4279 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4279 Gene

Variant ID Type Subtype PubMed ID
esv3604580 CNV gain 21293372
nsv1027907 CNV gain 25217958

Additional Variant Information for MIR4279 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4279
Leiden Open Variation Database (LOVD)
MIR4279

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4279 Gene

Disorders for MIR4279 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR4279 Gene - From: COP

Disorder Aliases PubMed IDs
asymptomatic dengue
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR4279

genes like me logo Genes that share disorders with MIR4279: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4279 Gene

Publications for MIR4279 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4279 Gene

Sources for MIR4279 Gene