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Aliases for MIR4274 Gene

Subcategory (RNA class) for MIR4274 Gene


Quality Score for this RNA gene is


Aliases for MIR4274 Gene

  • MicroRNA 4274 2 3 5
  • Hsa-Mir-4274 3

External Ids for MIR4274 Gene

Previous GeneCards Identifiers for MIR4274 Gene

  • GC04U901280

Summaries for MIR4274 Gene

Entrez Gene Summary for MIR4274 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4274 Gene

MIR4274 (MicroRNA 4274) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4274 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4274 Gene

Genomics for MIR4274 Gene

GeneHancer (GH) Regulatory Elements for MIR4274 Gene

Promoters and enhancers for MIR4274 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I007460 Enhancer 0.6 ENCODE 550.8 +0.8 761 0.2 USF1 RXRA BHLHE40 USF2 MNT RARA SKI MITF RAD51 NR2C1 MIR4274 PSAPL1 GC04M007519 SORCS2
GH04I007434 Promoter/Enhancer 1.2 EPDnew ENCODE 0.3 -24.4 -24379 2 SOX13 PKNOX1 SP5 ZNF189 CEBPB ZIC2 PPARG ZFP69B ZFHX2 GLIS2 PSAPL1 MIR4274 SORCS2
GH04I007463 Enhancer 0.4 ENCODE 0.8 +3.5 3491 1 CTCF FOXA2 RAD21 PSAPL1 MIR4274 GC04M007519 SORCS2
GH04I007508 Enhancer 0.3 FANTOM5 0.2 +48.3 48337 0 SORCS2 GC04M007519 MIR4274
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4274 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4274 Gene

Genomic Locations for MIR4274 Gene
91 bases
Plus strand

Genomic View for MIR4274 Gene

Genes around MIR4274 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4274 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4274 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4274 Gene

Proteins for MIR4274 Gene

Post-translational modifications for MIR4274 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4274 Gene

Domains & Families for MIR4274 Gene

Gene Families for MIR4274 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4274: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4274 Gene

Function for MIR4274 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4274 Gene

Localization for MIR4274 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4274 Gene

Pathways & Interactions for MIR4274 Gene

SuperPathways for MIR4274 Gene

No Data Available

Interacting Proteins for MIR4274 Gene

Gene Ontology (GO) - Biological Process for MIR4274 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4274 Gene

Drugs & Compounds for MIR4274 Gene

No Compound Related Data Available

Transcripts for MIR4274 Gene

mRNA/cDNA for MIR4274 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4274 Gene

No ASD Table

Relevant External Links for MIR4274 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4274 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4274 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4274 Gene:

genes like me logo Genes that share expression patterns with MIR4274: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4274 Gene

Orthologs for MIR4274 Gene

Evolution for MIR4274 Gene

Gene Tree for MIR4274 (if available)
Gene Tree for MIR4274 (if available)

No data available for Orthologs for MIR4274 Gene

Paralogs for MIR4274 Gene

No data available for Paralogs for MIR4274 Gene

Variants for MIR4274 Gene

Sequence variations from dbSNP and Humsavar for MIR4274 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1001162934 -- 7,459,696(+) C/T upstream_transcript_variant
rs1001477951 -- 7,458,183(+) T/C upstream_transcript_variant
rs1002349769 -- 7,458,990(+) A/G upstream_transcript_variant
rs1002492562 -- 7,459,548(+) C/T upstream_transcript_variant
rs1002830572 -- 7,460,453(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4274 Gene

Variant ID Type Subtype PubMed ID
esv34196 OTHER inversion 12058347
nsv469758 CNV loss 16826518
nsv508994 CNV insertion 20534489
nsv593569 CNV gain 21841781
nsv949781 CNV deletion 24416366

Additional Variant Information for MIR4274 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4274 Gene

Disorders for MIR4274 Gene

Additional Disease Information for MIR4274

No disorders were found for MIR4274 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4274 Gene

Publications for MIR4274 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. Decreased Expression of hsa-miR-4274 in Cerebrospinal Fluid of Normal Pressure Hydrocephalus Mimics with Parkinsonian Syndromes. (PMID: 27911315) Jurjević I … Arai H (Journal of Alzheimer's disease : JAD 2017) 3

Products for MIR4274 Gene

Sources for MIR4274 Gene

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