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Aliases for MIR4273 Gene

Subcategory (RNA class) for MIR4273 Gene


Quality Score for this RNA gene is


Aliases for MIR4273 Gene

  • MicroRNA 4273 2 3 5
  • Hsa-Mir-4273 3

External Ids for MIR4273 Gene

Previous GeneCards Identifiers for MIR4273 Gene

  • GC03U901568

Summaries for MIR4273 Gene

Entrez Gene Summary for MIR4273 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4273 Gene

MIR4273 (MicroRNA 4273) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4273 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4273 Gene

Genomics for MIR4273 Gene

GeneHancer (GH) Regulatory Elements for MIR4273 Gene

Promoters and enhancers for MIR4273 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I075784 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 0.2 +47.1 47103 1.7 HDAC1 TAF9B RB1 SIN3A ZNF76 ZBTB40 KLF5 YY1 ZNF121 POLR2B ZNF717 LINC00960 RPL23AP49 MIR4273
GH03I075781 Enhancer 0.6 ENCODE 0.3 +43.4 43364 0.9 SRF JUNB CBFA2T3 DPF2 BATF KLF5 IRF4 SP1 BCL11A ATF7 LINC00960 RPL23AP49 FAM86DP ZNF717 MIR4273
GH03I075782 Promoter 0.5 EPDnew 0.3 +44.1 44149 0.1 ZNF717 MIR4273
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4273 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4273 Gene

Genomic Locations for MIR4273 Gene
84 bases
Plus strand

Genomic View for MIR4273 Gene

Genes around MIR4273 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4273 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4273 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4273 Gene

Proteins for MIR4273 Gene

Post-translational modifications for MIR4273 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4273 Gene

Domains & Families for MIR4273 Gene

Gene Families for MIR4273 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4273: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4273 Gene

Function for MIR4273 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4273 Gene

Localization for MIR4273 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4273 Gene

Pathways & Interactions for MIR4273 Gene

SuperPathways for MIR4273 Gene

No Data Available

Interacting Proteins for MIR4273 Gene

Gene Ontology (GO) - Biological Process for MIR4273 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4273 Gene

Drugs & Compounds for MIR4273 Gene

No Compound Related Data Available

Transcripts for MIR4273 Gene

mRNA/cDNA for MIR4273 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4273 Gene

No ASD Table

Relevant External Links for MIR4273 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4273 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4273 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4273 Gene:

genes like me logo Genes that share expression patterns with MIR4273: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4273 Gene

Orthologs for MIR4273 Gene

Evolution for MIR4273 Gene

Gene Tree for MIR4273 (if available)
Gene Tree for MIR4273 (if available)

No data available for Orthologs for MIR4273 Gene

Paralogs for MIR4273 Gene

No data available for Paralogs for MIR4273 Gene

Variants for MIR4273 Gene

Sequence variations from dbSNP and Humsavar for MIR4273 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs193921040 uncertain-significance, Malignant tumor of prostate 75,738,395(+) G/C downstream_transcript_variant
rs1023979953 -- 75,736,932(+) A/T upstream_transcript_variant
rs1026802621 -- 75,737,106(+) T/C upstream_transcript_variant
rs1035705863 -- 75,736,684(+) C/A upstream_transcript_variant
rs10442977 -- 75,738,265(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4273 Gene

Variant ID Type Subtype PubMed ID
nsv956263 CNV deletion 24416366
nsv954891 CNV duplication 24416366
nsv822140 CNV loss 20364138
nsv822138 CNV gain 20364138
nsv821408 CNV duplication 20802225
nsv590725 CNV loss 21841781
nsv529016 CNV gain 19592680
nsv513053 CNV loss 21212237
nsv471427 CNV gain 19718026
nsv428418 CNV loss 18775914
nsv10283 CNV gain+loss 18304495
nsv1015074 CNV gain 25217958
nsv1012185 CNV loss 25217958
nsv1008795 CNV loss 25217958
nsv1008600 CNV gain 25217958
esv9630 CNV loss 19470904
esv3893725 CNV gain 25118596
esv3434335 CNV duplication 20981092
esv33470 CNV loss 17666407
esv2836125 CNV deletion 24192839
esv2763755 CNV gain+loss 21179565
esv2759157 CNV gain+loss 17122850
esv2725482 CNV deletion 23290073
esv2725481 CNV deletion 23290073
esv2725479 CNV deletion 23290073
esv2725478 CNV deletion 23290073
esv2725476 CNV deletion 23290073
esv26581 CNV gain+loss 19812545
esv2436311 CNV gain 19546169
esv2422315 CNV deletion 17116639
dgv8385n54 CNV gain 21841781
dgv812n67 CNV gain 20364138
dgv4795n100 CNV gain 25217958
dgv4794n100 CNV gain 25217958
dgv4790n100 CNV gain 25217958
dgv4773n100 CNV gain 25217958
dgv2722e59 CNV duplication 20981092
dgv2543n106 CNV deletion 24896259

Additional Variant Information for MIR4273 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4273 Gene

Disorders for MIR4273 Gene

Additional Disease Information for MIR4273

No disorders were found for MIR4273 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4273 Gene

Publications for MIR4273 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4273 Gene

Sources for MIR4273 Gene

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